Abstracts tagged "genetic architecture and juvenile idiopathic arthritis (JIA)"

Abstract Number: 137 • 2017 Pediatric Rheumatology Symposium
Chromatin Landscapes and Genetic Risk For Juvenile Idiopathic Arthritis
James Jarvis¹, Lisha Zhu², Lai Ping Wong³, Tao Liu⁴, Kaiyu Jiang³ and Yanmin Chen³, ¹Pediatrics, SUNY Buffalo School of Medicine, Buffalo, NY, ²Biochemistry, University at Buffalo, Buffalo, NY, ³Pediatrics, University at Buffalo, Buffalo, NY, ⁴Department of Biochemistry, University at Buffalo, Buffalo, NY
Background/Purpose: The transcriptomes of peripheral blood cells in children with juvenile idiopathic arthritis (JIA) show distinct transcriptional aberrations that suggest impairment of transcriptional regulation. To…
Abstract Number: 70 • 2016 ACR/ARHP Annual Meeting
Identifying Distal Interactions Between RUNX1 and JIA Associated Single Nucleotide Polymorphisms By Chromosome Conformation Capture
Christopher Taylor¹, Anne Hinks², Amanda McGovern¹, Helen Ray-Jones³, Kate Duffus¹, Annie Yarwood⁴, Gisela Orozco⁵, Paul Martin⁶, Wendy Thomson⁷ and Stephen Eyre⁸, ¹Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, ²ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ³Centre for Musculoskeletal Research, University of MAnchester, Manchester, United Kingdom, ⁴Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ⁵Arthritis Research UK, Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, United Kingdom, ⁶Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, United Kingdom, ⁷Arthritis Research UK Centre for Genetics and Genomics,The University of Manchester, Manchester, United Kingdom, ⁸The University of Manchester, Manchester, United Kingdom
Background/Purpose: 17 genetic loci have now been identified to confer susceptibility to JIA; several of these loci harbour genes involved in the IL2 pathway suggesting…
Abstract Number: 2410 • 2016 ACR/ARHP Annual Meeting
Genetic Architecture of Systemic Juvenile Idiopathic Arthritis Distinguishes It from Oligoarticular and Polyarticular Forms of Juvenile Idiopathic Arthritis
Michael J. Ombrello¹, Victoria Arthur¹, Elaine F. Remmers², Anne Hinks³, Alexei Grom⁴, Dirk Föll⁵, Alberto Martini⁶, Marco Gattorno⁷, Seza Ozen⁸, Sampath Prahalad⁹, Andrew Zeft¹⁰, John F. Bohnsack¹¹, Norman Ilowite¹², Ricardo Russo¹³, Elizabeth D. Mellins¹⁴, Claudio A. Len¹⁵, Maria Odete E. Hilário¹⁶, Sheila Oliveira¹⁷, Rae S.M. Yeung¹⁸, Alan Rosenberg¹⁹, Lucy R. Wedderburn²⁰, Jordi Anton²¹, Johannes Peter Haas²², Angela Rösen-Wolff²³, Klaus Tenbrock²⁴, Susan D Thompson²⁵, Daniel L. Kastner²⁶, Patricia Woo²⁷, Wendy Thomson²⁸ and International Childhood Arthritis Genetics (INCHARGE) Consortium, ¹Translational Genetics and Genomics Unit, NIAMS, NIH, Bethesda, MD, ²National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ³ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ⁴Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵University of Muenster, Muenster, Germany, ⁶Istituto Giannina Gaslini, Genoa, Italy, ⁷UO Pediatria 2, Istituto Giannina Gaslini, Genova, Italy, ⁸Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey, ⁹Pediatric Rheumatology, Emory University School of Medicine, Atlanta, GA, ¹⁰Pediatrics Rheumatology, Cleveland Clinic, Cleveland, OH, ¹¹Division of Allergy, Immunology and Pediatric Rheumatology, University of Utah, Salt Lake City, UT, ¹²Rheumatology, Children's Hospital Montefiore, Bronx, NY, ¹³Hospital de Pediatria Garrahan, Buenos Aires, Argentina, ¹⁴Dept of Pediatrics CCSR, Stanford University Med Ctr, Stanford, CA, ¹⁵Pediatrics, Universidade Federal de São Paulo, São Paulo,, Brazil, ¹⁶Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati, OH, ¹⁷Pediatric Rheumatology, Universidade F Rio De Janeiro, Rio De Janeiro, Brazil, ¹⁸Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁹Pediatrics, Pediatrics, Saskatoon, SK, Canada, ²⁰Institute of Child Health, UCL, London, United Kingdom, ²¹Unitat de Reumatologia Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain, ²²German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany, ²³Children's Hospital Dresden, Dresden, Germany, ²⁴University Aachen, Aachen, Germany, ²⁵Division of Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, ²⁶Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ²⁷Great Ormond Street Hospital, University College London Medical School, London, United Kingdom, ²⁸Arthritis Research UK Centre for Genetics and Genomics,The University of Manchester, Manchester, United Kingdom
Background/Purpose: JIA is a heterogeneous group of conditions that are unified by the presence of chronic childhood arthritis without an identifiable cause. Systemic JIA (sJIA)…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].