Abstracts tagged "Genetic adaptation"

Abstract Number: 91 • 2015 ACR/ARHP Annual Meeting
Coevolution of a Uric Acid Transporter and Uricase: Implications for Gout
Philip K. Tan¹, Eric A. Gaucher² and Jeffrey N. Miner³, ¹Ardea Biosciences, San Diego, CA, ²Georgia Institute of Technology, Atlanta, GA, ³Discovery Biology, Ardea Biosciences, San Diego, CA
Background/Purpose: Gout is caused by chronic hyperuricemia, leading to uric acid deposition. Humans and apes have relatively high serum uric acid (sUA) levels due to…

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Abstracts tagged "Genetic adaptation"

Coevolution of a Uric Acid Transporter and Uricase: Implications for Gout