Abstracts tagged "Gene Expression and cytokines"

Abstract Number: 963 • 2019 ACR/ARP Annual Meeting
Alterations of Memory and Naive B Cell Subsets Associate with Reduced IFNα and TNFRII in ANA+ Healthy Individuals
Aleksandra Bylinska¹, Samantha Slight-Webb ¹, Miles Smith ², Susan R. Macwana ¹, Nicolas Dominguez ¹, Eliza F. Chakravarty ³, Joan T. Merrill ⁴, Judith James ³ and Joel Guthridge ³, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, Oklahoma City, ³Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁴Okalahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Loss of systemic self-tolerance leading to anti-nuclear autoantibody (ANAs) by B cells is a hallmark of SLE. However, up to 20% of healthy female…

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Abstracts tagged "Gene Expression and cytokines"

Alterations of Memory and Naive B Cell Subsets Associate with Reduced IFNα and TNFRII in ANA+ Healthy Individuals