Abstracts tagged "gene-environmental interaction and LPG"

Abstract Number: 1998 • 2019 ACR/ARP Annual Meeting
Major Histocompatibility Antigen HLA-DQB1*0601 Is Associated with Rheumatoid Arthritis Among Indians in a Replication Study: Evidence of Gene-Environment Interaction with LPG Stove Use
Able Lawrence¹, Anshul Dhar ², Swayam Prakash ³, Suvrat Arya ⁴, Amita Aggarwal ⁵ and Suraksha Agrawal ⁶, ¹Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Lucknow, Uttar Pradesh, India, ²SGPGIMS, Lucknow, India, ³Cellular and Molecular Immunology Laboratory University of California Irvine, School of Medicine USA, Irvine, CA, ⁴Sanjay Gandhi Postgraduate Institute, Lucknow, India, Lucknow, India, ⁵Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India, ⁶SGPGIMS, Lucknow, Uttar Pradesh, India
Background/Purpose: Shared epitope smoking interaction does not fully explain MHC association in Rheumatoid Arthritis (RA). We have previously shown HLA-DQB1*0601 (DQ6.1) to be a susceptibility…

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