Abstracts tagged "gastrointestinal complications"

Abstract Number: 2718 • 2014 ACR/ARHP Annual Meeting
The UCLA Gastrointestinal Tract Questionnaire (GIT)2.0 and GI Visual Analogue Scale(GI-VAS) Reflect Different Aspects of GI Involvement in Systemic Sclerosis
Yossra Suliman^1,2, Yasser Shaweesh³, Suzanne Kafaja^4,5,6, Lewei Duan⁷ and Daniel E. Furst⁸, ¹Division of Rheumatology, Department of Medicine., David Geffen School of Medicine, University of California Los Angeles,, Los Angeles, CA, ²Rheumatology and Rehabilitation department, Faculty of Medicine, Assiut university, Assiut, Egypt, ³Division of Rheumatology, Department of Medicine., David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, ⁴Rheumatology, University of California Los Angeles, Los Angeles, CA, ⁵Medicine, University of California, Los Angeles, Department of Medicine, Los Angeles, CA, ⁶David Geffen School of Medicine, UCLA, Los Angeles, CA, ⁷David Geffen School of Medicine, University of California School of Medicine, Los Angeles, CA, ⁸University of California at Los Angeles, Los Angeles, CA
Background/Purpose UCLA GIT2.0 is a validated measure for assessing the severity of gastrointestinal involvement in systemic sclerosis patients (SSc) patients; GI VAS is also a…
Abstract Number: 1694 • 2014 ACR/ARHP Annual Meeting
a Feasibility Study of Subjective and Objective Assessment of Sublingual Abnormalities in Systemic Sclerosis
Tracy M. Frech¹, John Pauling², Maureen Murtaugh³, Lee S. Shapiro⁴, Bernard Choi⁵, Ryan Farraro⁵ and Robyn T. Domsic⁶, ¹Internal Medicine, Salt Lake City VAMC, Salt Lake, UT, ²Upper Borough Walls, Royal National Hospital for Rheumatic Disease, Bath, United Kingdom, ³Internal Medicine-Division of Epidemiology, University of Utah School of Medicine, SLC, UT, ⁴The Center for Rheumatology, Albany, NY, ⁵University of Irvine, Irvine, CA, ⁶Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Sublingual frenulum abnormalities are reported in systemic sclerosis (SSc), but the exact nature and clinical relevance of such abnormalities is unknown. Laser speckle contrast…
Abstract Number: 1677 • 2014 ACR/ARHP Annual Meeting
Association of Gastrointestinal Symptoms with Immunosuppressant Use in the Prospective Registry of Early Systemic Sclerosis Cohort
Tracy M. Frech¹, Maureen Murtaugh², Ami A. Shah³, Jessica K. Gordon⁴, Victoria K. Shanmugam⁵, Robyn T. Domsic⁶, Monique Hinchcliff⁷, Faye N. Hant⁸, Shervin Assassi⁹, Virginia D. Steen¹⁰ and Dinesh Khanna¹¹, ¹Internal Medicine, Salt Lake City VAMC, Salt Lake, UT, ²Internal Medicine-Division of Epidemiology, University of Utah School of Medicine, SLC, UT, ³Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Rheumatology, Hospital for Special Surgery, New York, NY, ⁵Rheumatology, The George Washington University, Washington, DC, ⁶Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁷Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁸Dept of Medicine, Medical Univ of South Carolina, Charleston, SC, ⁹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ¹⁰Department of Rheumatology, Georgetown University Medical Center, Washington, DC, ¹¹University of Michigan Health System, Ann Arbor, MI
Background/Purpose: The Prospective Registry of Early Systemic Sclerosis (PRESS) is a multicenter incident cohort study of patients with early diffuse cutaneous systemic sclerosis (dcSSc; <…
Abstract Number: 1323 • 2014 ACR/ARHP Annual Meeting
Gastrointestinal Involvement in Juvenile Systemic Sclerosis: Development of Recommendations for Screening and Investigation
Ivan Foeldvari¹, Clare Pain², Tamás Constantin³, Eileen Baildam⁴, Henning Lenhartz⁵, Michael Blakley⁶, Dana Nemkova⁷ and Clarissa A Pilkington⁸, ¹Department of Pediatric Rheumatology, Hamburger Zentrum für Kinder und Jugendrheumatologie, Hamburg, Germany, ²Pediatric Rheumatology, University Children´s Hospital, Liverpool, United Kingdom, ³Pediatric Rheumatology, University Childrens Hospital, Budapest, Hungary, ⁴Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, ⁵Pediatric Gastroenterology, Wilhelmstift, Hamburg, Germany, ⁶Internal Medicine and Pediatrics, Indiana University School of Medicine and Riley Hospital for Children at IU Health, Indianapolis, IN, ⁷Pedaitric Rheumatology, Prague, Czech Republic, ⁸Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
Background/Purpose There are currently no agreed recommendations on how to investigate children for gastrointestinal (GI) involvement in Juvenile Systemic Sclerosis (JSSc). The aim of screening…
Abstract Number: 750 • 2014 ACR/ARHP Annual Meeting
Molecular Characterization of Systemic Sclerosis Esophageal Pathology Identifies Inflammatory and Proliferative Signatures with Few Fibrotic Markers
Jaclyn Taroni¹, Viktor Martyanov², Chiang-Ching Huang³, J. Matthew Mahoney⁴, Ikuo Hirano⁵, Tammara A. Wood², Brandon Shetuni⁶, Guang-Yu Yang⁶, Darren Brenner⁵, Barbara Jung⁷, Swati Bhattacharyya⁸, Orit Almagor⁹, Jungwha Lee¹⁰, Arlene Sirajuddin¹¹, Rowland W. Chang¹², John Varga¹³, Michael Whitfield¹⁴ and Monique Hinchcliff¹⁵, ¹Genetics, Giesel School of Medicine at Dartmouth, Hanover, NH, ²Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, NH, ³Zilber School of Public Health, University of Wisconsin, Milwaukee, Milwaukee, WI, ⁴Department of Neurological Sciences, College of Medicine, University of Vermont, Burlington, VT, ⁵Department of Medicine, Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Department of Medicine, Division of Gastroenterology, University of Illinois at Chicago, Chicago, IL, ⁸Medicine/Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, ⁹Northwestern University, Chicago, IL, ¹⁰Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ¹¹Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, ¹²Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ¹³Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ¹⁴Geisel School of Medicine at Dartmouth, Hanover, NH, ¹⁵Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Esophageal involvement in patients with systemic sclerosis (SSc) is common, but tissue-specific pathological mechanisms are poorly understood. Esophageal muscle atrophy without concomitant fibrosis is…
Abstract Number: 729 • 2014 ACR/ARHP Annual Meeting
A Dilated Esophagus Is an Independent Risk Factor for Interstitial Lung Disease in SSc
Carrie Richardson¹, Rishi Agrawal², Jungwha Lee³, Orit Almagor⁴, John Varga⁵, Rowland W. Chang⁶ and Monique E. Hinchcliff⁷, ¹Department of Medicine, McGaw Medical Center of Northwestern University, Chicago, IL, ²Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Northwestern University, Chicago, IL, ⁵Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Northwestern University, Feinberg School of Medicine, Chicago, IL
Background/Purpose High-resolution computed tomography of the chest (HRCT) performed for assessment of interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) frequently reveals a…
Abstract Number: 462 • 2014 ACR/ARHP Annual Meeting
Infections and Gastrointestinal Side Effects in a Comparison of Rheumatoid Arthritis Therapies
Bei-Hung Chang^1,2, Lien Quach¹, Mary Brophy³, Keri Hannagan⁴, Edward C. Keystone⁵, Ted R. Mikuls⁶ and James R. O'Dell⁷, ¹VA Boston Healthcare System, Boston, MA, ²Qualitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, ³VA Boston Heathcare System, Boston, MA, ⁴MAVERIC, VA Boston Heathcare System, Boston, MA, ⁵Medicine, University of Toronto, Toronto, ON, Canada, ⁶Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁷Veteran Affairs Nebraska Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE
Background/Purpose TNF inhibitors and combinations of conventional disease-modifying antirheumatic drugs are commonly added to treat methotrexate non-responsive rheumatoid arthritis patients. In the 48-week double blind,…
Abstract Number: 2917 • 2013 ACR/ARHP Annual Meeting
Mortality, Recurrence, and Hospital Course of Patients With Systemic Sclerosis Related Acute Intestinal Pseudo-Obstruction
Chris T. Derk¹, Nora Sandorfi², Shivani Purohit³ and Christopher Mecoli⁴, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Division of Rheumatology, Thomas Jefferson Univ Med Coll, Philadelphia, PA, ³Rheumatology Division, Department of Medicine, Rheumatology Division, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, ⁴Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Acute intestinal pseudo-obstruction is a rare gastrointestinal manifestation of SSc with little data existing as to the demographics, clinical course, outcomes and mortality of…
Abstract Number: 2149 • 2013 ACR/ARHP Annual Meeting
Safety Of Lower-Dose Diclofenac Submicron Particle Capsules Dosed Up To 12 Weeks In Patients With Osteoarthritis
Clarence Young¹ and Marc C. Hochberg², ¹Iroko Pharmaceuticals, Philadelphia, PA, ²Medicine, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Osteoarthritis (OA) is the most common cause of disability in the US and is frequently managed with non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs, including diclofenac,…
Abstract Number: 439 • 2013 ACR/ARHP Annual Meeting
Tofacitinib, An Oral Janus Kinase Inhibitor: Analysis Of Gastrointestinal Adverse Events Across The Rheumatoid Arthritis Clinical Program
E. B. Lee¹, J. R. Curtis², R. Riese³, C. A. Connell³, R. Chew³, M.G. Boy³, E. Maller⁴, C. Su⁴ and L. Wang³, ¹Seoul National University, Seoul, South Korea, ²Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ³Pfizer Inc, Groton, CT, ⁴Pfizer Inc, Collegeville, PA
Background/Purpose: Tofacitinib is a novel, oral Janus kinase inhibitor being investigated as a targeted immunomodulator in rheumatoid arthritis (RA). This analysis aimed to describe and…
Abstract Number: 389 • 2013 ACR/ARHP Annual Meeting
Small Intestine Enteropathy In Patients With Rheumatoid Arthritis and Osteoarthritis, Taking Regularly Non-Steroidal Antirheumatic Drugs . Has The Basic Disease Effect On Incidence and Degree Of Damage?
Petr Bradna¹, Ilja Tachecí², Drahomira Bastecka³, Stanislav Rejchrt³, Jan Bures⁴ and Marcela Kopacova⁵, ¹2nd Gastroenterological Department of Internal Medicine, Charles University Prague Faculty of Medicine Hradec Kralove and University Hospital, Hradec Králové, Czech Republic, ²Charles University Prague Faculty of Medicine Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic, ³2nd Gastroenterological Department of Internal Medicine, Charles University Prague Faculty of Medicine Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic, ⁴Charles University Prague,Medical Faculty Hradec Kralove and University Hospital, Hradec Kralove, Hradec Kralove, Czech Republic, ⁵2nd Gastroenterological Department of Internal Medicine, Charles University Prague, Medical Faculty Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic
Background/Purpose: The involvement of small intestine is demonstrable up to 72% of patients, using non-steroidal antirheumatic drugs (NSAIDs). Quite a few is known about the…
Abstract Number: 2374 • 2012 ACR/ARHP Annual Meeting
Characteristics, Treatment and Outcome of Gastrointestinal Involvement in Behcet’s Syndrome: Experience in A Dedicated Center
Ibrahim Hatemi¹, Gulen Hatemi², Yusuf Erzin¹, Aykut Ferhat Celik¹ and Hasan Yazici³, ¹Istanbul University, Cerrahpasa Medical School, Istanbul University, Cerrahpasa Medical School, Gastroenterology, Istanbul, Turkey, ²Istanbul University, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ³Istanbul University, Cerrahpasa Medical School, Istanbul University, Cerrahpasa Medical School, Rheumatology, Istanbul, Turkey
Background/Purpose: Gastrointestinal involvement can be a severe complication resulting in perforation and massive bleeding. Controlled data regarding treatment is lacking and long term prognosis is…

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