ACR Meeting Abstracts

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Abstracts tagged "gastrointestinal complications"

  • Abstract Number: 2898 • 2016 ACR/ARHP Annual Meeting

    Anti-Reflux Medications in Diffuse Cutaneous Systemic Sclerosis:  Is Empiric Use of Proton Pump Inhibitors Supported?

    Tracy M. Frech1, Ami A. Shah2, Monique Hinchcliff3, Flavia V. Castelino4, Shervin Assassi5, Elana J. Bernstein6, Robyn T. Domsic7, Jessica K. Gordon8, Victoria K. Shanmugam9,10, Virginia D. Steen11, Maureen Murtaugh12, Bernie LaSalle13, Dinesh Khanna14 and Faye N. Hant15, 1Division of Rheumatology, University of Utah, Salt Lake City, UT, 2Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Northwestern University, Feinberg School of Medicine Scleroderma Program, Chicago, IL, 4Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 5Department of Internal Medicine - Rheumatology, University of Texas-McGovern Medical School, Houston, TX, 6Department of Medicine, Division of Rheumatology, Columbia University, New York, NY, 7Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, 8Rheumatology, Hospital for Special Surgery, New York, NY, 9Rheumatology, George Washington University, Great Falls, VA, 10Division of Rheumatology, The George Washington University, Washington, DC, 11Rheumatology, Georgetown University Medical Center, Washington, DC, 12University of Utah, Salt Lake, UT, 13University of Utah, Salt Lake City, UT, 14University of Michigan, Ann Arbor, MI, 15Medicine/Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC

    Background/Purpose: Table 1: PRESS
  • Abstract Number: 2902 • 2016 ACR/ARHP Annual Meeting

    Preliminary Evaluation of Gastroesophageal Reflex Disease Outcome Measures in Scleroderma– Scleroderma Clinical Trials Consortium Gastrointestinal Working Group

    Zsuzsanna McMahan1, Tracy M. Frech2, Guya Piemonte3, Marco Matucci-Cerinic4, Susanna Proudman5,6, Veronica J. Berrocal7, Ron Hays8 and Dinesh Khanna9, 1Department of Internal Medicine, Johns Hopkins University, Baltimore, MD, 2Division of Rheumatology, University of Utah, Salt Lake City, UT, 3University of Florence, Florence, Italy, 4Department of Medicine, Division of Rheumatology, University of Florence, Florence, Italy, 5Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia, 6Discipline of Medicine, University of Adelaide, Adelaide, Australia, 7Div of Rheumatology, University of Michigan, Ann Arbor, MI, 8UCLA, Los Angeles, CA, 9University of Michigan, Ann Arbor, MI

    Background/Purpose: Gastrointestinal tract (GIT) involvement occurs in approximately 95% of patients with systemic sclerosis (SSc). There is consensus in the Scleroderma Clinical Trials Consortium (SCTC)…
  • Abstract Number: 2911 • 2016 ACR/ARHP Annual Meeting

    A Comparison of Gastrointestinal Disease Severity in African American and Caucasian Scleroderma Patients

    Carolyn Fridley1 and Virginia D. Steen2, 1Rheumatology, Georgetown University, Washington, DC, 2Rheumatology, Georgetown University Medical Center, Washington, DC

    A Comparison of Gastrointestinal Disease Severity in African American and Caucasian Scleroderma Patients Background/Purpose: Systemic sclerosis (SSc) is a multisystem autoimmune disease. After skin involvement…
  • Abstract Number: 827 • 2016 ACR/ARHP Annual Meeting

    Severe Gastrointestinal Disease in Early Systemic Sclerosis Is Associated with an Increased Risk of Mortality

    Nicolas Richard1, Marie Hudson2, Mianbo Wang3, Murray Baron4, Genevieve Gyger1 and Canadian Scleroderma Research Group, 1McGill University, Jewish General Hospital, Montreal, QC, Canada, 2Medicine/Rheumatology, Jewish General Hospital, Lady Davis Research Institute, Montreal, QC, Canada, 3Lady Davis Institute for Medical Research, Montreal, QC, Canada, 4Rheumatology, McGill University, Jewish General Hospital, Montreal, QC, Canada

    Background/Purpose: Studies of severe gastrointestinal (GI) disease in systemic sclerosis (SSc) are limited by small, selected samples composed largely of subjects with prevalent disease. We…
  • Abstract Number: 838 • 2016 ACR/ARHP Annual Meeting

    Esophageal Dysmotility and Interstitial Lung Disease in Patients with Scleroderma: A Retrospective Study

    Shweta Kishore1, Santhanam Lakshminarayanan1, Chia-Ling Kuo2 and Ranadeep Mandhadi1, 1Division of Rheumatology, University of Connecticut, Farmington, CT, 2Department of Community Medicine and Health Care, University of Connecticut, Farmington, CT

    Background/Purpose: Systemic sclerosis (SSc) is a connective tissue disease with pulmonary involvement seen in 75% of patients and esophageal involvement in 90% of the patients.…
  • Abstract Number: 839 • 2016 ACR/ARHP Annual Meeting

    Immunosuppression Does Not Prevent Severe Gastrointestinal Disease in Systemic Sclerosis

    Nicolas Richard1, Marie Hudson2, Mianbo Wang3, Murray Baron4, Genevieve Gyger1 and Canadian Scleroderma Research Group, 1McGill University, Jewish General Hospital, Montreal, QC, Canada, 2Medicine/Rheumatology, Jewish General Hospital, Lady Davis Research Institute, Montreal, QC, Canada, 3Lady Davis Institute for Medical Research, Montreal, QC, Canada, 4Rheumatology, McGill University, Jewish General Hospital, Montreal, QC, Canada

    Background/Purpose: Severe gastrointestinal (GI) disease is associated with considerable morbidity and high mortality in systemic sclerosis (SSc). There are no known preventative treatments. We wished…
  • Abstract Number: 974 • 2016 ACR/ARHP Annual Meeting

    Diffuse Scleroderma, Male Sex, and Myopathy Are Associated with Severe Gastrointestinal Dysmotility in Scleroderma

    Zsuzsanna McMahan1, Livia Casciola-Rosen2 and Fredrick M. Wigley3, 1Department of Internal Medicine, Johns Hopkins University, Baltimore, MD, 2Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Rheum Div/Mason F Lord, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Despite the fact that up to 90% of scleroderma (SSc) patients are affected by gastrointestinal (GI) dysmotility, features associated with severe GI disease are…
  • Abstract Number: 1853 • 2016 ACR/ARHP Annual Meeting

    Klf5+/-;Fli1+/- Mice Recapitulate Protracted Wound Healing and Cardiac and Intestinal Involvement Associated with Systemic Sclerosis

    Kouki Nakamura1, Yoshihide Asano2, Takuya Miyagawa3, Megumi Hirabayashi3, Takashi Yamashita3, Ryosuke Saigusa1, Shunsuke Miura2, Tetsuo Toyama3,4, Takehiro Takahashi1, Yohei Ichimura1, Takashi Taniguchi1, Ayumi Yoshizaki3, Maria Trojanowska4 and Shinichi Sato1, 1Dermatology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, 2University of Tokyo Graduate School of Medicine, Tokyo, Japan, 3Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, 4Arthritis Center, Boston University, Arthritis Center, Boston, MA

    Background/Purpose: Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by vasculopathy and tissue fibrosis. Although the most recognizable manifestation is skin disease, SSc can…
  • Abstract Number: 829 • 2015 ACR/ARHP Annual Meeting

    Fecal Incontinence and Association with Bowel Dysfunction in Systemic Sclerosis: A Canadian Multicenter Study

    Nicolas Richard1,2, Marie Hudson2, Genevieve Gyger2, Murray Baron3, Evelyn Sutton4, Nader A. Khalidi5, Janet E. Pope6, Nathalie Carrier1, Maggie J. Larche5, Alexandra Albert7, Paul R. Fortin7, Carter Thorne8, Ariel Masetto9 and Canadian Scleroderma Research Group, 1Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, 2McGill University, Jewish General Hospital, Montreal, QC, Canada, 3Rheumatology, McGill University, Jewish General Hospital, Montreal, QC, Canada, 4Rheumatology, Dalhousie University, Nova Scotia Rehabilitation Centre, Halifax, NS, Canada, 5McMaster University, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 6Monsignor Roney Bldg/Rheum, University of Western Ontario, St Joseph Health Care, London, ON, Canada, 7Université Laval, CHU de Québec, Québec, QC, Canada, 8Southlake Regional Health Centre, Newmarket, ON, Canada, 9Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada

    Background/Purpose: Gastrointestinal (GI) tract involvement is a common and serious complication of systemic sclerosis (SSc). However, the prevalence of fecal incontinence (FI) and its relationship…
  • Abstract Number: 831 • 2015 ACR/ARHP Annual Meeting

    Mycophenolate Decreases the Frequency of Endoscopic Therapy for Gastric Antral Vascular Ectasia in Patients with Systemic Sclerosis

    Tiffany Lin1, James Bena2, Shannon Morrison2 and Soumya Chatterjee3, 1Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, 2Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Gastric antral vascular ectasia (GAVE) is an increasingly recognized cause of upper gastrointestinal bleeding in patients with systemic sclerosis (SSc).  These patients may require…
  • Abstract Number: 940 • 2015 ACR/ARHP Annual Meeting

    NOD2-Associated Autoinflammatory Disease: Therapy and Outcomes

    Qingping Yao1 and Bo Shen2, 1Cleveland Clinic, Cleveland, OH, 2Gastroenterology, Cleveland Clinic, Cleveland, OH

    Background/Purpose: NOD2-associated autoinflammatory disease, now redesignated as Yao Syndrome(YS) is a newly described and increasingly recognized entity. It is characterized by periodic fever, dermatitis, polyarthritis, sicca-like…
  • Abstract Number: 2978 • 2015 ACR/ARHP Annual Meeting

    Longitudinal Assessment of Gastrointestinal Symptoms in the Prospective Registry of Early Systemic Sclerosis Cohort

    Tracy M. Frech1, Maureen Murtaugh2, Jessica K. Gordon3, Robyn T. Domsic4, Ami A. Shah5, Faye N. Hant6, Shervin Assassi7, Monique E. Hinchcliff8, Elana J. Bernstein9, Virginia D. Steen10, Victoria K. Shanmugam11,12 and Dinesh Khanna13, 1Div of Rheumatology, University of Utah, Salt Lake City, UT, 2University of Utah, Salt Lake, UT, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, 5Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 6Dept of Medicine, Medical University of South Carolina, Charleston, SC, 7Rheumatology, University of Texas Medical School at Houston, Houston, TX, 8Division of Rheumatology, Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 9Columbia University, New Yory, NY, 10Rheumatology, Georgetown University Medical Center, Washington, DC, 11Director, Division of Rheumatology, The George Washington University, Washington, DC, 12Division of Rheumatology, The George Washington University, Washington, DC, 13Division of Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose: The Prospective Registry of Early Systemic Sclerosis (PRESS) is a multicenter incident cohort study of patients with early diffuse cutaneous systemic sclerosis (dcSSc; <…
  • Abstract Number: 2979 • 2015 ACR/ARHP Annual Meeting

    Laser Speckled Imaging and Videomicroscopy Assessment of Sublingual Perfusion in Systemic Sclerosis and Healthy Controls

    Mark Sievert1, Daniel R. Machin2, Anthony J. Donato2, Maureen Murtaugh3, John D. Pauling4, Robyn T. Domsic5, Lee S. Shapiro6 and Tracy M. Frech7, 1University of Utah, Salt Lake City, UT, 2University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake, UT, 3University of Utah, Salt Lake, UT, 4Upper Borough Walls, Royal National Hospital for Rheumatic Disease, Bath, United Kingdom, 5Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, 6Steffens Scleroderma Center, Albany, NY, 7Div of Rheumatology, University of Utah, Salt Lake City, UT

    Background/Purpose: Our group has previously described the sublingual frenulum abnormalities in systemic sclerosis (SSc, scleroderma).   The goal of this project was to assess microvascular abnormalities…
  • Abstract Number: 3129 • 2015 ACR/ARHP Annual Meeting

    Integrative Analysis of the Colonic Microbiota in Systemic Sclerosis

    Elizabeth R. Volkmann1, Yu-Ling Chang2, Nashla Barroso3, Daniel E. Furst3, Philip J. Clements1, Alan Gorn4, Bennett Roth3, Jeffrey Conklin3, Terri Getzug3, Maomeng Tong2, Jonathan Jacobs3 and Jonathan Braun2, 1Medicine, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 2Pathology and Laboratory Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 3Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 4Medicine, UCLA David Geffen School of Medicine, Division of Rheumatology, Los Angeles, CA

    Background/Purpose: Gastrointestinal tract (GIT) dysfunction is a leading cause of morbidity in patients with systemic sclerosis (SSc). However, the etiology of SSc-related lower GIT dysfunction…
  • Abstract Number: 3136 • 2015 ACR/ARHP Annual Meeting

    Impact of Prokinetic Agents on Systemic Sclerosis-Associated Gastrointestinal Disease: A Systematic Review

    Annaliese Tisseverasinghe1, Ahmad Kadhim2, Ambica Parmar2, Louis Liu2 and Sindhu R. Johnson1, 1Toronto Scleroderma Program, Division of Rheumatology, Toronto Western Hospital, Mount Sinai Hospital, Institue of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, 2Division of Gastroenterology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: More than 90% of patients with Systemic Sclerosis (SSc) have gastroinstestinal (GI) involvement, commonly dysmotility causing complications such as gastroesophageal reflux and constipation. Treatment…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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