Abstracts tagged "fractures and hematopoietic stem cells"

Abstract Number: 47 • 2012 ACR/ARHP Annual Meeting
Accumulation of CD34+ Hematopoietic Stem Cells in the Initial Inflammatory Human Fracture Hematoma Is Mediated Via Chemokine Receptor Type 3 Ligands
Paula Hoff¹, Timo Gaber¹, Martin Hahne¹, Cindy Strehl¹, Katharina Schmidt-Bleek², Gerd Burmester³, Gerhard Schmidmaier⁴, Georg Duda⁵, Carsten Perka⁶ and Frank Buttgereit⁷, ¹Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ²Julius Wolff Institut, Charité University Medicine, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Department of Traumatology, Heidelberg University Hospital, Heidelberg, Germany, ⁵Julius Wolff Institute, Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁶Center of Muscoloskeletal Surgery, Charité University Medicine, Berlin, Germany, ⁷Charité - Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: We have previously shown the early phase of human fracture healing to be characterized by hypoxia which promotes inflammation and chemoattraction. Hypoxia is also…

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