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Abstracts tagged "fractures"

  • Abstract Number: 1149 • ACR Convergence 2021

    Efficacy of Alendronate for Prevention of New Fractures and Vertebral Deformities in Patients with Rheumatologic Disorders on Chronic Glucocorticoid Therapy: A Systematic Review and Meta-analysis

    Saffa Iftikhar1, Waleed Khokher2, Ashu Acharya1, Joan Gekonde3, Nithin Kesireddy2, Rawish Fatima1 and Nezam Altorok2, 1University of Toledo Medical Center, Toledo, OH, 2University of Toledo, Toledo, OH, 3University of Toledo, Sylvania Township, OH

    Background/Purpose: Glucocorticoids are commonly used in patients with rheumatologic conditions including but not limited to Rheumatoid Arthritis, Polymyalgia Rheumatica, Systemic Lupus Erythematous and so on.…
  • Abstract Number: 272 • 2019 ACR/ARP Annual Meeting

    Osteoporosis Management Outcomes in a Southern California County Health System

    Lorien Ahn1, Jordan Thompson 1, Nancy Collado 2, Micah Yu 2, Anna Lafian 2, Christina Downey, MD 3 and Karina Torralba 4, 1Loma Linda University, Loma linda, 2Loma Linda University Medical Center, loma linda, 3Loma Linda University Medical Center, Loma LInda, CA, 4Loma Linda University School of Medicine, Loma Linda, CA

    Background/Purpose: Fragility fractures (FF) are a sentinel event in osteoporosis and world-wide only 20% of patients with a FF receive treatment, a large care gap.…
  • Abstract Number: 1929 • 2019 ACR/ARP Annual Meeting

    Identification and Validation of Transcriptional Genes Associated with Osteoporotic Vertebral Fractures by Microarray Study, in Community Elderly Women

    Levi Jales Neto1, Zofia Wicik 2, Georgea Torres 1, Liliam Takayama 1, Neusa Lopes 1, alexandre Pereira 1 and Rosa Pereira 3, 1University of Sao Paulo, Sao Paulo, Brazil, 2University of Sao Paulo, São Paulo, Brazil, 3Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil

    Background/Purpose: The pathogenesis of osteoporosis, a common disease with high morbidity1, comprises genetic and environmental factors2. Recent studies demonstrated that blood samples are a source…
  • Abstract Number: 2204 • 2019 ACR/ARP Annual Meeting

    Fragility Fractures in a Community Setting: Clinical Characteristics, Care Gaps, and Outcomes

    Rachel Kneeland1, Keile Wahle 1, Ishwar Gill 1, Yangyang Liu 2 and Monika Starosta 3, 1Department of Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, IL, 2Russell Center for Research & Innovation, Advocate Lutheran General Hospital, Park Ridge, IL, 3Department of Rheumatology, Advocate Lutheran General Hospital, Park Ridge, IL

    Background/Purpose: Osteoporosis-related fragility fractures contribute to significant morbidity and mortality. The risk of subsequent hip fracture is significantly increased after initial fracture, with some reports…
  • Abstract Number: 270 • 2019 ACR/ARP Annual Meeting

    Outcomes of a Fracture Liaison Service at an Academic Health Center

    Micah Yu1, Donna Jose 2, Parke Hudson 2, Christina Downey, MD 3, Wesley Phipatanakul 2, Silvana Giannelli 2, Kevin Codorniz 4 and Karina Torralba 5, 1Loma Linda University Medical Center, loma linda, 2Loma Linda University, Loma Linda, 3Loma Linda University Medical Center, Loma LInda, CA, 4[email protected], Loma Linda, 5Loma Linda University School of Medicine, Loma Linda, CA

    Background/Purpose: Osteoporosis is associated with increased morbidity and mortality.  There is a 60% risk of a subsequent fracture for patients who have had one fracture,…
  • Abstract Number: 2174 • 2018 ACR/ARHP Annual Meeting

    Self-Report of Fracture History Compared to Fracture Codes from an Electronic Health Record Dataset

    Maria I. Danila1, Amy S. Mudano1, Elizabeth J. Rahn2, Andrea Z. LaCroix3,4, Jeffrey R. Curtis1 and Kenneth Saag1, 1University of Alabama at Birmingham, Birmingham, AL, 2Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3University of California San Diego, La Jolla, CA, 4Group Health Cooperative, Seattle, WA

    Background/Purpose: Self-reported fracture (fx) history data is frequently used in epidemiological studies of osteoporosis. Self-reported fx data may differ from fx history coded in electronic…
  • Abstract Number: 2305 • 2018 ACR/ARHP Annual Meeting

    Peripheral Arterial Disease Is Associated with an Increased Risk of Subsequent Hip Fracture: A Systematic Review and Meta-Analysis of Cohort Studies

    Patompong Ungprasert1, Karn Wijarnpreecha2, Charat Thongprayoon2 and Wisit Cheungpasitporn3, 1Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Internal medicine, Bassett medical center, cooperstown, NY, 3Medicine, University of Mississippi Medical center, Jackson, MS

    Peripheral Arterial Disease is Associated with an Increased Risk of Subsequent Hip Fracture: A Systematic Review and Meta-Analysis of Cohort Studies             AbstractBackground/Purpose: Studies have suggested…
  • Abstract Number: 2307 • 2018 ACR/ARHP Annual Meeting

    In the 21st Century: Is Still Rheumatoid Arthritis a Risk Factor for Osteoporotic Fractures?

    Florencia Pierini1, Luciano Fernando Lo Giudice2, Marina Scolnik3, Javier Rosa2, Valeria Scaglioni3 and Enrique R Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, CABA, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Capital Federal, Argentina, 3Rheumatology Unit, Internal Medicine Service. Hospital Italiano Buenos Aires. Argentina, Buenos Aires, Argentina

    Background/Purpose: Rheumatoid Arthritis (RA) has been considered an independent osteoporotic risk factor. Nowadays, RA patients have a better disease control and corticosteroid use is less…
  • Abstract Number: 2308 • 2018 ACR/ARHP Annual Meeting

    Abaloparatide for Risk Reduction of Nonvertebral and Vertebral Fractures in Postmenopausal Women with Osteoporosis: A Network Meta-Analysis

    Jean Yves Reginster1, Florence Bianic2, Rosanne Campbell2, Monique Martin2, Setareh A. Williams3 and Lorraine A Fitzpatrick3, 1Université de Liège, Liège, Belgium, 2inVentiv Health, London, United Kingdom, 3Radius Health, Inc., Waltham, MA

    Background/Purpose: To assess the relative efficacy of abaloparatide compared with other osteoporosis treatment options (alendronate, denosumab, ibandronate, raloxifene, risedronate, romosozumab, strontium ranelate, teriparatide, zoledronic acid).…
  • Abstract Number: 2326 • 2018 ACR/ARHP Annual Meeting

    Outcomes One Year after Hip Fracture Repair in the Elderly: Does Social Isolation Matter?

    Lisa A. Mandl1, Serena Lian1, Jackie Szymonifka2, Kirsten Grueter3, Aidan Hadad3 and Joseph Lane3, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Orthopaedic Surgery, Hospital for Special Surgery, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over age 65. Social isolation—how integrated a patient…
  • Abstract Number: 2335 • 2018 ACR/ARHP Annual Meeting

    Osteoporotic Fracture Trends in a Population of US Managed Care Enrollees: 2007-2017

    E. Michael Lewiecki1, Benjamin Chastek2, Kevin Sundquist2, Setareh A. Williams3, Deane Leader Jr.3, Richard Weiss3, Yamei Wang3, Lorraine A Fitzpatrick3 and Jeffrey R. Curtis4, 1New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, 2Optum, Eden Prairie, MN, 3Radius Health, Inc., Waltham, MA, 4University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Osteoporosis-related fractures (fractures) are a leading cause of morbidity and disability in the US. Epidemiological data on the occurrence of fractures are limited and…
  • Abstract Number: 2337 • 2018 ACR/ARHP Annual Meeting

    Vertebral Compression Fractures and Antibodies to Citrullinated Vimentin in Established Rheumatoid Arthritis

    Jonathan Cheah1,2, John A. Carrino3,4, William H. Robinson5,6, Dana Orange7,8, Jackie Szymonifka9, Emily M. Stein1,2 and Susan M. Goodman9,10, 1Medicine, Hospital for Special Surgery, New York, NY, 2Medicine, Weill Cornell Medicine, New York, NY, 3Radiology, Hospital for Special Surgery, New York, NY, 4Radiology, Weill Cornell Medicine, New York, NY, 5VA Palo Alto Health Care System, Palo Alto, CA, 6Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, 7Rheumatology, Hospital for Special Surgery, New York, NY, 8Rockefeller University, New York, NY, 9Hospital for Special Surgery, New York, NY, 10Rheumatology, Weill Cornell Medicine, New York, NY

    Background/Purpose: Patients with RA have high rates of osteoporosis and fractures and RA induces articular and extra-articular bone loss. Seropositivity for any CCP antibody is…
  • Abstract Number: 2809 • 2018 ACR/ARHP Annual Meeting

    Skeletal Benefit/Risk of Long-Term Denosumab Therapy: A Virtual Twin Analysis of Fractures Prevented to Skeletal Safety Events Observed

    Serge Ferrari1, E. Michael Lewiecki2, Peter W. Butler3, David L Kendler4, Nicola Napoli5, Shuang Huang3, Daria B Crittenden3, Nicola Pannacciulli3, E.S. Siris6 and Neil Binkley7, 1Geneva University Hospital, Geneva, Switzerland, 2New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, 3Amgen Inc., Thousand Oaks, CA, 4University of British Columbia, Vancouver, BC, Canada, 5Campus Bio-Medico University of Rome, Rome, Italy, 6Columbia University Medical Center, New York, NY, 7University of Wisconsin–Madison Osteoporosis Clinical Center and Research Program, Madison, WI

    Background/Purpose: Osteoporosis is a chronic disease, yet skeletal safety events—atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ)—remain a concern with long-term treatment. Ten…
  • Abstract Number: 326 • 2017 ACR/ARHP Annual Meeting

    Osteoporosis and Vertebral Fractures Are Associated with Disease Activity, Low Vitamin D Levels and Spinal Radiographic Damage in Patients with Axial Spondyloarthritis

    Cintia Romera-López1, Cristina Fernández-Carballido2, Miguel Ángel García-Moreno3 and Teresa Pedraz4, 1Rheumatology, Hospital Universitario del Vinalopó, Elche, Spain, 2Hospital General Universitario de Elda, Elda, Spain, 3Hosppital Universitario de Elda, Elda, Spain, 4Hospital Universitario de Elda, Elda, Spain

    Background/Purpose: Osteoporosis and vertebral fractures are comorbidities of Axial Spondyloarthritis (axSpA). We evaluated the relationship between disease activity and radiographic damage and bone mineral density…
  • Abstract Number: 328 • 2017 ACR/ARHP Annual Meeting

    Secular Trends in the Risk of Fragility Fracture Among Patients with Rheumatoid Arthritis: A General Population-Based Study

    Sarah Keller1, Marcy B. Bolster2, Amar Oza3, Sharan K. Rai4, Leo Lu3, Yuqing Zhang5 and Hyon K. Choi4, 1Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Allergy, Immunology, and Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 5Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The risk of osteoporotic (OP) fracture among patients with rheumatoid arthritis (RA) is higher than that of the general population. The worldwide incidence of…
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