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Abstracts tagged "flow cytometry and systemic lupus erythematosus (SLE)"

  • Abstract Number: 2691 • ACR/ARHP Annual Meeting 2014

    A Novel CD123–CD11c– Dendritic Cell Subset Increased in Relation to Disease Activity in Patients with Systemic Lupus Erythematosus

    Satoshi Kubo1, Shingo Nakayamada1, Naoki Yunoue1, Maiko Yoshikawa1, Kunihiro Yamaoka1 and Yoshiya Tanaka2, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2University of Occupational and Environmental Health, Japan, Kitakyushu, Japan

    Background/Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by overproduction of autoantibodies by B cells and breaking self-tolerance of T cells and dendritic…
  • Abstract Number: 1623 • ACR/ARHP Annual Meeting 2014

    Increased CD95 (Fas) Expression on Naive B Cells Is Associated with a Switch to Double Negative and Plasma Cells in the Peripheral Blood, and Correlates with Disease Activity in Systemic Lupus Erythematosus

    Julie Ducreux1, Séverine Nieuwland2, Frédéric A. Houssiau1 and Bernard R. Lauwerys1, 1Institut de Recherche Expérimentale et Clinique, Pôle de Maladies Rhumatismales, Université catholique de Louvain, Brussels, Belgium, 2Institut de Recherche Expérimentale et Clinique, Pôle de pathologies rhumatismales, Université catholique de Louvain, Brussels, Belgium

    Background/Purpose: systemic lupus erythematosus (SLE) is characterized by a break of tolerance to autoantigens, and polyclonal activation of B cells. We performed multicolor flow cytometry…
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