Abstracts tagged "fibromyalgia"

Abstract Number: 2233 • ACR Convergence 2022
Machine Learning Uncovers Novel mRNAs Expressed in Fibromyalgia
Lena Kolb¹, Mark Rudolph¹, Alan Kivitz², Scott Rey¹, Roberta Alexander¹, Anja Kammesheidt³ and Geoffrey Stephens¹, ¹Exagen, Inc., Vista, CA, ²Department of Rheumatology, Altoona Center for Clinical Research, Duncansville, PA, ³self, Laguna Beach, CA
Background/Purpose: Fibromyalgia is a debilitating pain condition that affects roughly 12 million people in the United States. Although preliminary diagnostic criteria have been established by…
Abstract Number: 0733 • ACR Convergence 2022
Median Patient Global Assessment Varies Far More According to FAST4 (fibromyalgia Assessment Screening Tool) and MDS2 (MDHAQ Depression Screen) on a Single MDHAQ (multidimensional Health Assessment Questionnaire) Than According to Primary Diagnosis
Theodore Pincus¹, Kathryn Gibson², Juan Schmukler¹, Tengfei Li³ and Joel Block¹, ¹Rush University Medical Center, Chicago, IL, ²Liverpool Hospital, Sydney, Australia, ³Georgetown University, Washington, DC
Background/Purpose: Patient global assessment (PATGL) is a component of DAS28 (disease activity score 28) and CDAI (clinical disease activity index) to assess patients with rheumatoid…
Abstract Number: 2235 • ACR Convergence 2022
Clinical Impact of a Digital Behavioral Therapy for Fibromyalgia Management in a Decentralized Trial
Yifei Dai¹, Michael Rosenbluth², Michael Gendreau³, Nicolette Vega⁴, Zunera Ghalib⁴, Allison Kraus⁴ and Brian Keefe⁵, ¹Swing Therapeutics, Gainesville, FL, ²Swing Therapeutics, San Francisco, CA, ³GENDREAU CONSULTING, LLC, Poway, CA, ⁴Swing Therapeutics, San Francisco, ⁵Swing Therapeutics, New York, NY
Background/Purpose: Cognitive behavioral therapy (CBT) has demonstrated level 1A evidence for management of fibromyalgia (FM). Acceptance and Commitment Therapy (ACT), a form of CBT, has…
Abstract Number: 1216 • ACR Convergence 2022
Subclinical Vascular Disease Is More Prevalent in above-30 Adult Fibromyalgia: A Preliminary Report of a Hospital-based Cross-sectional Study from South India
Salil Ganu, C. B. Mithun and Jyothi Visalakshy, Amrita Institute of Medical Sciences, Kochi, India
Background/Purpose: Fibromyalgia is known to be associated with cardiovascular events and mortality. We aimed to compare the prevalence of subclinical atherosclerosis (SAT), a surrogate marker…
Abstract Number: 2236 • ACR Convergence 2022
Association of microRNA-30b Plasma Expression with Fibromyalgia Clinical Features and with Corneal Small Nerve Fiber Pathology
Laura Aline Martínez Martínez¹, Fausto Sánchez Muñoz¹, Manuel Ramírez Fernández², Yaneli Juárez Vicuña¹, Mario Peña-Peña¹, Carlos Alfonso Guzman Martin¹, Itzel Palafox Sosa¹ and Manuel Martínez-Lavín¹, ¹Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, Mexico, ²APEC Hospital de la ceguera, Ciudad de México, Mexico
Background/Purpose: There is a clear association between fibromyalgia and small fiber neuropathy. Dorsal root ganglia contain the small nerve fiber nuclei. Severe fibromyalgia is associated…
Abstract Number: 1218 • ACR Convergence 2022
Prevalence and Impact of Widespread Pain and Fibromyalgia on Measurement of Disease Severity in Psoriatic Arthritis: Lessons from the CorEvitas Registry
Philip J Mease¹, Alexis Ogdie², Dimitrios Pappas³, George Reed⁴ and Joel Kremer⁵, ¹Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, ²Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ³CorEvitas, LLC, Waltham, MA, ⁴The Corrona Research Foundation and University of Massachusetts, Albany, NY, ⁵The Corrona Research Foundation, Delray Beach, FL
Background/Purpose: Fibromyalgia (FM) occurs concomitantly with inflammatory rheumatic disease, including psoriatic arthritis (PsA), in up to 20% of patients and chronic widespread pain (CWP) in…
Abstract Number: 2256 • ACR Convergence 2022
Increased Brain Functional Connectivity to the Insula Is Associated with Nociplastic Pain in Psoriatic Arthritis
Flavia Sunzini¹, Kristian Stefanov¹, Salim Al-Wasity¹, Steven E Harte², Richard E Harris², Daniel J Clauw², Stefan Siebert³, Carl Goodyear¹, Gordon Waiter⁴ and Neil Basu¹, ¹University of Glasgow, Glasgow, Scotland, United Kingdom, ²University of Michigan, Ann Arbor, MI, ³Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, Scotland, United Kingdom, ⁴University of Aberdeen, Aberdeen, Scotland, United Kingdom
Background/Purpose: Pain is a hallmark feature of psoriatic arthritis (PsA); however, its apparent multi-factorial nature makes it difficult for rheumatologists to assess and manage. Clinically,…
Abstract Number: 1219 • ACR Convergence 2022
Gender-Related Clinical Profile of Fibromyalgia Patients
Mark Berman¹, Liane banon², Omer Shlezinger³, Laurence Mangel⁴, Jacob Ablin¹ and Valerie Aloush⁵, ¹Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ²Department of Gastroenterology and Hepatolgy, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ³Internal Medicine F, Tel Aviv, Israel, ⁴Sackler faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁵Tel Aviv Medical Center, Tel Aviv, Israel
Background/Purpose: Fibromyalgia is a chronic pain disorder characterized by widespread pain, fatigue, sleep disturbances, cognitive dysfunction and frequent psychiatric comorbidities. Estimated prevalence of fibromyalgia is…
Abstract Number: 1220 • ACR Convergence 2022
Autonomic Dysfunction in Sjogren’s Disease
Ardy Fenando¹, Jordan Estes¹, Maha Mohamad¹, Sareena Shah², John Lee², Duaa Jabari¹, Joshua Baker³ and Ghaith Noaiseh¹, ¹University of Kansas Medical Center, Kansas City, KS, ²University of Missouri-Kansas City, Kansas City, MO, ³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Sjogren's Disease (SjD) is a heterogenous autoimmune disease associated with debilitating symptoms. Autonomic dysfunction (AD) is common in SjD and may contribute to symptom…
Abstract Number: 0127 • ACR Convergence 2021
Interleukin 1 Receptor Antagonist (IL-1Ra) Variable Number of Tandem Repeat (VNTR) Polymorphism in Fibromyalgia Patients in South India
Arun Tiwari¹, Mithun CB², Lalitha Biswas³, Sandeep Surendran³, Vishal Marwaha³, Pranav Chickermane³ and Amisha Shahul³, ¹Amrita Institute of Medical Sciences, Ernakulam, India, ²Amrita Institute of Medical Sciences, Muvattupuzha, India, ³Amrita Institute of Medical Sciences, Kochi, India
Background/Purpose: Interleukin-1 receptor antagonist (IL-1Ra) variable number of tandem repeats (VNTR) polymorphism is a known to influence the production of IL-1Ra and has been considered…
Abstract Number: 0474 • ACR Convergence 2021
Correlation of Fibromyalgia Survey Questionnaire and Quantitative Sensory Testing Among Patients with Active Rheumatoid Arthritis
Meriah Moore¹, Beth Wallace², Jing Song³, Lutfiyya Muhammad⁴, Andrew Heisler⁵, Daniel Clauw¹, Marcy Bolster⁶, Wendy Marder¹, Tuhina Neogi⁷, Alyssa Wohlfahrt⁸, Dorothy Dunlop⁹ and Yvonne Lee⁹, ¹University of Michigan, Ann Arbor, MI, ²Michigan Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, ³Northwestern University, Worthington, IL, ⁴Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Bronson Rheumatology Specialists, Kalamazoo, MI, ⁶Massachusetts General Hospital, Boston, MA, ⁷Boston University School of Medicine, Boston, MA, ⁸Tufts University School of Medicine, Boston, MA, ⁹Northwestern University, Chicago, IL
Background/Purpose: Patients with rheumatoid arthritis (RA) commonly demonstrate disordered pain processing, termed central sensitization (CS). CS is typically measured using quantitative sensory testing (QST), which…
Abstract Number: 0475 • ACR Convergence 2021
Quantitative Analysis of Gender and Racial Disparities in Randomized Controlled Trials of Fibromyalgia
Rami Diab¹, Ali Malik², Mahmoud Al Rifai³ and Dennis Ang⁴, ¹Wake Forest Baptist Health/Wake Forest School of Medicine, Winston-Salem, NC, ²Wake Forest Baptist Health / Wake Forest School of Medicine, Winston-Salem, NC, ³Baylor College of Medicine, Houston, TX, ⁴Wake Forest School of Medicine, Winston-Salem, NC
Background/Purpose: Fibromyalgia is a chronic pain syndrome characterized by widespread musculoskeletal pain, mood disorders, fatigue, and cognitive and sleep disturbance. Mainstay treatments include tricyclic antidepressants,…
Abstract Number: 0476 • ACR Convergence 2021
Factors Associated with Pain Reduction and Improved Well-Being Among Fibromyalgia Patients Using Medical Cannabis
Marc Martel¹, Lilach Eyal Waldman¹, Romina Sotoodeh¹, Antonio Vigano¹, Yola Moride², Michelle Canac-Marquis³, Rihab Gamaoun³, Maja Kalaba⁴, Pierre Beaulieu², Julie Desroches², Mark A. Ware⁴, Jordi Perez³, Yoram Shir³ and Mary-Ann Fitzcharles¹, ¹McGill University, Montréal, QC, Canada, ²Université de Montréal, Montréal, QC, Canada, ³McGill University Health Centre, Montréal, QC, Canada, ⁴Canopy Growth Corporation, Montréal, QC, Canada
Background/Purpose: Fibromyalgia (FM) is characterized by a constellation of symptoms that are often poorly responsive to current treatments, and patients are increasingly turning to medical…
Abstract Number: 0477 • ACR Convergence 2021
TNX-102 SL (Sublingual Cyclobenzaprine) for the Treatment of Fibromyalgia in the RELIEF Study: Positive Results of a Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter Efficacy and Safety Trial
Gregory Sullivan¹, Mary Kelley², Annabelle Iserson¹, Perry Peters², Ashild Peters², Candace Flint¹, Judy Gendreau³, Herb Harris¹, Ben Vaughn⁴ and Seth Lederman⁵, ¹Tonix Pharmaceuticals, Inc., Chatham, NJ, ²Tonix Pharmaceuticals, Inc., San Diego, CA, ³Gendreau Consulting, LLC, Poway, CA, ⁴Rho, Inc., Cary, NC, ⁵Tonix Pharmaceuticals, Inc., South Dartmouth, MA
Background/Purpose: Fibromyalgia (FM) is characterized by chronic widespread pain, fatigue, and nonrestorative sleep, a symptom constellation suggestive of a pathological disturbance in central pain processing…
Abstract Number: 0659 • ACR Convergence 2021
Understanding the Rheumatologic Population We Serve Through Objective Analysis of Referrals and Diagnoses: Does Perception Match Actual Data?
Kirsten Koons¹, Jonida Cote², Sanjeev Shrestha³, Melissa Band³, David Pugliese⁴ and Eric Newman³, ¹Geisinger Medical Center, Lewisburg, PA, ²Geisinger Medical Center, Orefield, PA, ³Geisinger Medical Center, Danville, PA, ⁴Geisinger Medical Center, Wilkes Barre, PA
Background/Purpose: Healthcare access in our Rheumatology Department is challenging. Fibromyalgia is perceived to occupy a large portion of clinic visits, leading to increased wait times…

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