Abstracts tagged "fibromyalgia"

Abstract Number: 867 • 2012 ACR/ARHP Annual Meeting
Events That Trigger the Onset of the Fibromyalgia Syndrome (FMS)
Robert S. Katz¹, Sharon M. Ferbert², Alexandra Small³ and Susan Shott¹, ¹Rush University Medical Center, Chicago, IL, ²Advocates for Funding Fibromyalgia Treatment, Education and Research(AFFTER), Libertyville, IL, ³University of Illinois Medical School, Chicago, IL
Background/Purpose: Triggering events – those that are followed by the onset or rapid increase in FMS symptoms – have a significant impact in some cases. …
Abstract Number: 2646 • 2012 ACR/ARHP Annual Meeting
Cost-Effectiveness of Tai Chi Mind-Body Exercise for the Treatment of Fibromyalgia
John B. Wong¹ and Chenchen Wang², ¹Medicine/Clinical Decision Making, Tufts Medical Center, Boston, MA, ²Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Although fibromyalgia is associated with substantial annual direct medical and indirect productivity costs, the cost-effectiveness of treatments for fibromyalgia remains understudied. A randomized…
Abstract Number: 1868 • 2012 ACR/ARHP Annual Meeting
Clinical Outcome in Fibromyalgia Patients Treated with Milnacipran Is Largely Independent of Symptom Duration
Philip J. Mease¹, Robert M. Bennett², Robert H. Palmer³ and Yong Wang⁴, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Medicine & Nursing, Oregon Health & Science University, Portland, OR, ³Forest Research Institute, Inc., Jersey City, NJ, ⁴Forest Research Institute, Jersey City, NJ
Background/Purpose: Patients with fibromyalgia (FM) usually experience pain, fatigue, and other debilitating symptoms for years. In clinical studies ranging from 3 months to >3 years,…
Abstract Number: 802 • 2012 ACR/ARHP Annual Meeting
Milnacipran Reduces Brain Activity During Pain in Fibromyalgia
Anson E. Kairys¹, Richard E. Harris², Eric Ichesco², Johnson P. Hampson², Steven Harte², Daniel J. Clauw³ and Tobias Schmidt-Wilcke², ¹Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI
Background/Purpose: Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain and a number of concomitant symptoms such as fatigue, sleep disturbance, cognitive…
Abstract Number: 1875 • 2012 ACR/ARHP Annual Meeting
A Patient and Physician Survey of Impact and Management of Fibromyalgia Across Latin America and Europe
Patricia Clark, Unidad de Epidemilogia Clinica, Hospital Infantil de México Federico Gómez, Mexico City, Mexico
Background/Purpose: Differences in healthcare practices around the world have been reported; however any impact on management of chronic conditions is often unclear. We surveyed patients…
Abstract Number: 803 • 2012 ACR/ARHP Annual Meeting
Frontal Brain Connectivity to the Default Mode Network Is Associated with Subjective Fatigue Irrespective of Pain and Depression
Johnson P. Hampson¹, Daniel J. Clauw², Jieun Kim³, Vitaly Napadow⁴ and Richard E. Harris¹, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, ⁴Radiology, Martinos Center for Biomedical Imaging, Charlestown, MA
Background/Purpose: Chronic pain patients report increased levels of fatigue; however, very little is known about the underlying mechanisms of this symptom. Previous work by our…
Abstract Number: 2641 • 2012 ACR/ARHP Annual Meeting
Time-to-Improvement of Pain and Sleep in Clinical Trials of Pregabalin Treatment of Fibromyalgia
Lesley M. Arnold¹, Andrew Clair², Birol Emir², Lynne Pauer² and E. Malca Resnick², ¹Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, ²Pfizer Inc, New York, NY
Background/Purpose: Fibromyalgia (FM) is a chronic condition characterized by widespread pain and tenderness. Sleep disturbance is common in patients with FM, and both pain and…
Abstract Number: 1857 • 2012 ACR/ARHP Annual Meeting
Identifying Core Symptom Domains in the Fibromyalgia Impact Questionnaire: Principal Component Analysis of Data From Milnacipran Clinical Studies
Philip J. Mease¹, Robert M. Bennett², Robert H. Palmer³ and Yong Wang⁴, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Medicine & Nursing, Oregon Health & Science Univ, Portland, OR, ³Forest Research Institute, Inc., Jersey City, NJ, ⁴Forest Research Institute, Jersey City, NJ
Background/Purpose: The Fibromyalgia Impact Questionnaire (FIQ) is a multidimensional instrument that encompasses many of the core domains recommended by OMERACT for evaluation in fibromyalgia (FM)…
Abstract Number: 804 • 2012 ACR/ARHP Annual Meeting
A Comparison of the Nociceptive Flexion Reflex, Pressure Algometry and Summated Widespread Pain in the Diagnosis of Fibromyalgia
Robert M. Bennett¹, Kim D. Jones² and Janice Hoffman³, ¹Medicine & Nursing, Oregon Health & Science Univ, Portland, OR, ²Research & Develop, Oregon Health Sciences University, Portland, OR, ³Office of Research Development & Support, Oregon Health & Science University, Portland, OR
Background/Purpose: To reevaluate the usefulness of the nociceptive flexion reflex (NFR) in distinguishing between FM patients and healthy controls, compared to computerized algometry and a…
Abstract Number: 2644 • 2012 ACR/ARHP Annual Meeting
Functional Magnetic Resonance Imaging of Working Memory in Fibromyalgia: Support for a “Competing Demands” Theory of Cognitive Function in Chronic Pain
Anson E. Kairys¹, Gabriela Ramirez¹, Eric Ichesco², Johnson P. Hampson², Richard E. Harris², Daniel J. Clauw³, Tobias Schmidt-Wilcke² and Jennifer M. Glass⁴, ¹Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ⁴Psychiatry, University of Michigan, Ann Arbor, MI
Background/Purpose: The primary symptom of fibromyalgia (FM) is chronic widespread pain; however, patients report additional symptoms including decreased concentration and memory. Deficits are seen mainly…
Abstract Number: 1858 • 2012 ACR/ARHP Annual Meeting
Hypervigiliance in Fibromyalgia
Robert S. Katz¹, Ben J. Small², Susan Shott¹ and Sharon M. Ferbert³, ¹Rush University Medical Center, Chicago, IL, ²MacNeal Hospital, Berwyn, IL, ³Advocates for Funding Fibromyalgia Treatment, Education and Research(AFFTER), Libertyville, IL
Background/Purpose: Patients with fibromyalgia syndrome (FMS) experience severe chronic pain and usually are tender to touch. They are hyperactive to weather changes and stress. Do…
Abstract Number: 805 • 2012 ACR/ARHP Annual Meeting
Milnacipran Increases Cortical to Brainstem Connectivity During Pain in Fibromyalgia
Eric Ichesco¹, Tobias Schmidt-Wilcke¹, Anson E. Kairys², Johnson P. Hampson¹, Steven E. Harte¹, Daniel J. Clauw³ and Richard E. Harris¹, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ³Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI
Background/Purpose: Fibromyalgia (FM) is a chronic widespread pain disorder characterized by muscle tenderness, fatigue, poor sleep, and mood disturbance. Milnacipran is a dual serotonin-norepinephrine reuptake…
Abstract Number: 2450 • 2012 ACR/ARHP Annual Meeting
Evoked Pain Brain Response Is Associated with Reduced μ-Opioid Receptor Binding in Fibromyalgia
Heng Wang¹, Daniel J. Clauw², Jon-Kar Zubieta³ and Richard E. Harris⁴, ¹Anesthesiology, University of Michigan, Ann Arbor, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Molecular and Behavioral Neuroscience Institue, Psychiatry, University of Michigan, Ann Arbor, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Previous studies indicate that fibromyalgia (FM) patients have augmented clinical and brain responses to painful stimuli (i.e. hyperalgesia/allodynia), as well as increased production of…
Abstract Number: 1566 • 2012 ACR/ARHP Annual Meeting
Fibromyalgia’s Impact On Relationships
Robert S. Katz¹, Alexandra Small², Sharon M. Ferbert³ and Susan Shott¹, ¹Rush University Medical Center, Chicago, IL, ²University of Illinois Medical School, Chicago, IL, ³Advocates for Funding Fibromyalgia Treatment, Education and Research(AFFTER), Libertyville, IL
Background/Purpose: The Fibromyalgia Syndrome (FMS) can place a strain on patients’ personal relationships. Having a close support network is helpful in coping with illnesses, but chronic…
Abstract Number: 806 • 2012 ACR/ARHP Annual Meeting
Posterior Insula Combined Glutamate and Glutamine Is Associated with Pain in Fibromyalgia: A Replication Study
Eric Ichesco¹, Daniel J. Clauw², Steven E. Harte¹, Anson E. Kairys³, Johnson P. Hampson¹, Tobias Schmidt-Wilcke¹ and Richard E. Harris¹, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI
Background/Purpose: Central pain augmentation resulting from enhanced excitatory and/or decreased inhibitory neurotransmission is a proposed mechanism underlying the pathophysiology of functional pain syndromes such as…

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