Abstracts tagged "fibromyalgia"

Abstract Number: 1879 • 2012 ACR/ARHP Annual Meeting
Work Related Injuries Causing or Aggravating Fibromyalgia in the Medicolegal Arena: A Jurisprudential Analysis
Mary-Ann Fitzcharles¹, Peter A. Ste-Marie² and Yoram Shir³, ¹Rheumatology and Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, ²University of Montreal, Montreal, QC, Canada, ³Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Up to 40% of persons report onset of fibromyalgia (FM) following a “triggering event”. Injuries, which may occur in the workplace, may be implicated…
Abstract Number: 960 • 2012 ACR/ARHP Annual Meeting
Cyclobenzaprine (CBP) and Its Major Metabolite Norcyclobenzaprine (nCBP) Are Potent Antagonists of Human Serotonin Receptor 2a (5HT2a), Histamine Receptor H-1 and á-Adrenergic Receptors: Mechanistic and Safety Implications for Treating Fibromyalgia Syndrome by Improving Sleep Quality
Bruce Daugherty, Leland Gershell and Seth Lederman, Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: Bedtime cyclobenzaprine (CBP) improves fibromyalgia symptoms (pain, fatigue, tenderness, and mood) and improves sleep quality (decreases Cyclic Alternating Pattern Type A2 + A3) (1).…
Abstract Number: 1881 • 2012 ACR/ARHP Annual Meeting
Increased Psychosocial Stress Is a Major Component of Fibromyalgia Triggers
Emma K. Guymer¹, Kathleen Elford² and Geoffrey O. Littlejohn³, ¹Rheumatology and Medicine, Monash Medical Centre and Monash University, Clayton, Victoria, Australia, ²Rheumatology, Monash Medical Centre, Clayton, Victoria, Australia, ³Rheumatology, Monash Medical Centre and Monash University, Clayton, VIC, Australia
Background/Purpose: Fibromyalgia is a common, chronic pain disorder. Initial development of symptoms occurs under conditions unique to each patient. Psychological and physical triggers are recognized,…
Abstract Number: 963 • 2012 ACR/ARHP Annual Meeting
Efficacy of Long-Term Milnacipran Treatment in Patients Meeting Different Thresholds of Clinically Relevant Pain Relief: Subgroup Analysis of a Double-Blind, Placebo-Controlled Discontinuation Study
Daniel J. Clauw¹, Philip J. Mease², Robert H. Palmer³, Joel M. Trugman⁴ and Yimin Ma⁴, ¹Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ²Swedish Medical Center and University of Washington, Seattle, WA, ³Forest Research Institute, Inc., Jersey City, NJ, ⁴Forest Research Institute, Jersey City, NJ
Background/Purpose: Patients with fibromyalgia (FM) who received up to 3.25 years of milnacipran (MLN) in a flexible-dose (≤200 mg/d) open-label (OL) study were eligible to…
Abstract Number: 1882 • 2012 ACR/ARHP Annual Meeting
Predictors of a Favorable Outcome in Patients with Fibromyalgia: Results From the 1-Year Follow-up
Dong-Jin Park¹, Shin-Seok Lee², Seong-Ho Kim³, Seong-Su Nah⁴, Ji Hyun Lee⁵, Seong-Kyu Kim⁶, Yeon-Ah Lee⁷, Seung-Jae Hong⁷, Hyun-Sook Kim⁸, Hye-Soon Lee⁹, Hyoun Ah Kim¹⁰, Chung-Il Joung¹¹ and Sang-Hyon Kim¹², ¹Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ²Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ³Department of Internal Medicine,, Inje University Haeundae Paik Hospital, Busan, South Korea, ⁴Rheumatology, Soonchunhyang University, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, South Korea, ⁶Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ⁸Internal Medicine, Chosun University Hospital, Gwangju, South Korea, ⁹Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ¹⁰Ajou University Hospital, Suwon, South Korea, ¹¹Department of Internal Medicine, Konyang university hospital, Daejeon, South Korea, ¹²Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea
Background/Purpose: To determine the outcomes in Korean patients with fibromyalgia (FM) and identify the prognostic factors associated with improvement at 1-year follow-up. Methods: Forty-eight patients…
Abstract Number: 967 • 2012 ACR/ARHP Annual Meeting
Haplotypes of GTP Cyclophydrolase Gene Polymorphisms Are Protective in the Susceptibility of Fibromyalgia Syndrome
Hwajeong Lee¹, Shin-Seok Lee², Seong-Kyu Kim³, Jung-Yoon Choe⁴, Seong-Ho Kim KIM⁵, Seong-Su Nah⁶, Ji Hyun Lee⁷, Seung-Jae Hong⁸, Hyun-Sook Kim⁹, Hye-Soon Lee¹⁰, Hyun Ah Kim¹¹ and Chung-Il Joung¹², ¹Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, ²Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ³Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁵Department of Internal Medicine,, Inje University Haeundae Paik Hospital, Busan, South Korea, ⁶Department of Internal Medicine, Soonchunhyang University, College of Medicine, Cheonan, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, South Korea, ⁸Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ⁹Internal Medicine, Chosun University Hospital, Gwangju, South Korea, ¹⁰Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ¹¹Division of Rheumatology, Department of Internal Medicine, Hallym university, Kyunggi, South Korea, ¹²Department of Internal Medicine, Konyang university hospital, Daejeon, South Korea
Background/Purpose: Guanosine triphosphate cyclohydrolase 1 (GCH1) is the rate-limiting enzyme in the synthesis of tetrahydrobiopterin, which is an essential co-factor in nitric oxide (NO) production.…
Abstract Number: 1860 • 2012 ACR/ARHP Annual Meeting
Fibromyalgia and the Disease and Statistical Manual Classification As a Somatic Symptom Disorder
Frederick Wolfe¹, Brian T. Walitt² and Winfried Häuser³, ¹National Data Bank for Rheumatic Diseases, Wichita, KS, ²Rheumatology, Washington Hospital Center, Washington, DC, ³Department of Psychosomatic Medicine and Psychotherapy, Technische Universität München, Munich, Germany
Background/Purpose: Fibromyalgia was first defined by rheumatologists, and is often thought of as a disorder of widespread pain and decreased pain threshold. In the wider…
Abstract Number: 952 • 2012 ACR/ARHP Annual Meeting
Cognitive Behavioral Therapy and Milnacipran in Combination Appears to Be More Efficacious Than Either Therapy Alone
Dennis C. Ang¹, Mark P. Jensen², Jennifer L. Steiner³, Janna Hilligoss¹, Richard Gracely⁴ and Chandan Saha⁵, ¹Indiana University, Indianapolis, IN, ²Rehabilitation, University of Washington, Seattle, WA, ³Psychology, Indiana University Purdue University Indianapolis, Indianapolis, IN, ⁴Dentistry, University of North Carolina, Chapel Hill, NC, ⁵Biostatistics, Indiana University
Background/Purpose: The two treatment options that have received the significant attention in fibromyalgia (FM) management are cognitive behavioral therapy (CBT) and medications. Given the fact…
Abstract Number: 1865 • 2012 ACR/ARHP Annual Meeting
Emotional Pain and Catastrophizing Influence Quality of Life in Fibromyalgia
Neda Faregh¹, Peter A. Ste-Marie² and Mary-Ann Fitzcharles³, ¹McGill University, Montreal, QC, Canada, ²Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, ³Rheumatology and Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Fibromyalgia (FM) is a composite of symptoms with the pivot symptom of pain, traditionally measured as intensity with little attention to other qualities. Emotional…
Abstract Number: 953 • 2012 ACR/ARHP Annual Meeting
Comparative Symptom Severity of Patients Satisfying Chronic Widespread Pain and Fibromyalgia Criteria
Frederick Wolfe¹, Brian Wallitt², Robert S. Katz³ and Winfried Häuser⁴, ¹National Data Bank for Rheumatic Diseases, Wichita, KS, ²Washington Hospital Center, Baltimore, MD, ³Rush University Medical Center, Chicago, IL, ⁴Klinikum Saarbrücken, Saarbrücken, Germany
Background/Purpose: Chronic widespread pain (CWP) is often used as a surrogate for fibromyalgia in epidemiological research, particularly in Europe and in whiplash-related injuries. This CWP…
Abstract Number: 1866 • 2012 ACR/ARHP Annual Meeting
Association of Opioid Use with Symptom Severity and Quality of Life in Patients with Fibromyalgia
Terry H. Oh¹, Chul H. Kim², Connie A. Luedtke³, Jeffrey Thompson¹, W. Michael Hooten⁴ and Ann Vincent⁵, ¹Pm&r, Mayo Clinic, Rochester, MN, ²Kyungpook National University, Daegu, South Korea, ³Nursing, Mayo Clinic, Rochester, MN, ⁴Anesthesiology, Mayo Clinic, Rochester, MN, ⁵General Internal Medicine, Mayo Clinic, Rochester, MN
Background/Purpose: Chronic widespread pain is a cardinal symptom in patients with fibromyalgia. Current pharmacotherapies for fibromyalgia targets central neurochemical abnormalities and pain processing pathways. Analgesics…
Abstract Number: 866 • 2012 ACR/ARHP Annual Meeting
Pain Is Associated with Telomere Shortening in Women with Fibromyalgia
Afton L. Hassett¹, Daniel J. Clauw², Richard E. Harris¹, Steven E. Harte¹, Anson E. Kairys³, Steven Buyske⁴ and David A. Williams⁵, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ⁴Statistics, Rutgers University, Piscataway, NJ, ⁵Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI
Background/Purpose: Telomere length is considered a marker of cellular aging and has been linked to an increased risk for morbidity and mortality. Psychosocial factors associated…
Abstract Number: 1867 • 2012 ACR/ARHP Annual Meeting
Assessment of ART Therapy Program for Women with Fibromyalgia: Randomized, Controlled, Blinded Study
Andreia S. Baptista¹, Anamaria Jones¹, Fernanda P. Cardoso¹, Betina C. Schaffir¹, Elisa R. W. Coelho¹, Aline Orlandi¹ and Jamil Natour², ¹Unifesp-EPM, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Fibromyalgia (FM) is a chronic non-inflammatory syndrome characterized by diffuse pain throughout the body, sleep disorder, stiffness, fatigue, depression and other psychological problems. Patients…
Abstract Number: 867 • 2012 ACR/ARHP Annual Meeting
Events That Trigger the Onset of the Fibromyalgia Syndrome (FMS)
Robert S. Katz¹, Sharon M. Ferbert², Alexandra Small³ and Susan Shott¹, ¹Rush University Medical Center, Chicago, IL, ²Advocates for Funding Fibromyalgia Treatment, Education and Research(AFFTER), Libertyville, IL, ³University of Illinois Medical School, Chicago, IL
Background/Purpose: Triggering events – those that are followed by the onset or rapid increase in FMS symptoms – have a significant impact in some cases. …
Abstract Number: 2646 • 2012 ACR/ARHP Annual Meeting
Cost-Effectiveness of Tai Chi Mind-Body Exercise for the Treatment of Fibromyalgia
John B. Wong¹ and Chenchen Wang², ¹Medicine/Clinical Decision Making, Tufts Medical Center, Boston, MA, ²Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Although fibromyalgia is associated with substantial annual direct medical and indirect productivity costs, the cost-effectiveness of treatments for fibromyalgia remains understudied. A randomized…

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