Abstracts tagged "fibromyalgia"

Abstract Number: 78 • 2015 ACR/ARHP Annual Meeting
Exploratory Analysis of Somatic Symptoms in Fibromyalgia By Multidimensional Scaling and Latent Class Analysis
Marco Antivalle¹, Michele Battellino¹, Alberto Batticciotto¹, MariaChiara Ditto¹, Alessandra Mutti¹, Valentina Varisco¹, Federica Rigamonti¹, Fabiola Atzeni¹ and Piercarlo Sarzi-Puttini², ¹Rheumatology, L. Sacco University Hospital, Milano, Italy, ²Rheumatology Unit, L. Sacco University Hospital, Milano, Italy
Background/Purpose: Attempts to individuate subsets of fibromyalgia patients based on the aggregation of different symptoms have so far produced conflicting results. The 2010 preliminary diagnostic…
Abstract Number: 2301 • 2015 ACR/ARHP Annual Meeting
Facing Fibromyalgia; How Patients Describe Their Symptoms Based on a Retrospective Evaluation of a Patient Survey and Vitality Assessment in Clinical Trials
Andrew Clair¹, Lynne Pauer² and Elizabeth Masters¹, ¹Pfizer Inc., New York, NY, ²Pfizer Inc, New London, CT
Background/Purpose: Fibromyalgia (FM) is a common chronic widespread pain disorder with comorbid symptoms of fatigue, sleep disturbance, cognitive dysfunction and depression. It is believed to…
Abstract Number: 80 • 2015 ACR/ARHP Annual Meeting
Paresthesias in Fibromyalgia Patients
Robert S. Katz¹, Lauren Kwan², Kelli Davis² and Jessica L. Polyak², ¹Rush University Medical Center, Chicago, IL, ²Rheumatology Associates S.C., Chicago, IL
Background/Purpose: Paresthesias are common in patients with fibromyalgia. We evaluated the symptoms of numbness and tingling in fibromyalgia patients and rheumatic disease controls without…
Abstract Number: 2302 • 2015 ACR/ARHP Annual Meeting
The Impact of Prior Fibromyalgia Treatment on the Response to Pregabalin in Fibromyalgia Clinical Trials
Lynne Pauer¹, Andrew Clair², Pritha Bhadra Brown², Marie Ortiz² and Joseph Scavone¹, ¹Pfizer Inc, Groton, CT, ²Pfizer Inc., New York, NY
Background/Purpose: Fibromyalgia (FM) is a chronic, widespread pain disorder for which Lyrica is an approved treatment. Antidepressants, gabapentin, muscle relaxants, and opioids are frequently used…
Abstract Number: 84 • 2015 ACR/ARHP Annual Meeting
Sexual Dimorphism in the Association Between Multi-Site Pain and Other Fibromyalgia Features: an Analysis of Data from Three UK Population-Based Studies
Linda E. Dean¹, Lesley Arnold², Robert Bennett³, Leslie J. Crofford⁴, Don Goldenberg⁵, Elisa Flüß¹, Daniel J. Clauw⁶, Mary-Ann Fitzcharles⁷, Eduardo Paiva⁸, Roland Staud⁹ and Gary J. Macfarlane¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²University of Cincinnati, Cincinnati, OH, ³SN-Office of Research & Development, Oregon Health & Science Univ, Portland, OR, ⁴Medicine, Vanderbilt University, Nashville, TN, ⁵Newton-Wellesley Hospital, Newton, MA, ⁶Anesthesiology, University of Michigan, Ann Arbor, MI, ⁷MGH, Montreal, QC, Canada, ⁸Rheumatology, Universidade Federal do Parana, Curitiba Parana, Brazil, ⁹University of Florida, Gainesville, FL
Background/Purpose: The 2011 modification of the preliminary 2010 American College of Rheumatology criteria for fibromyalgia require the self-report of multi-site pain in addition to a…
Abstract Number: 2305 • 2015 ACR/ARHP Annual Meeting
Relationship Between Anxiety, Depression, Sleep, Fibromyalgia and BMI in Patients with Rheumatic Disease
Shazia Bég¹ and Ali Ahmad², ¹Rheumatology, University of Central Florida, Orlando, FL, ²University of Central Florida, Orlando, FL
Background/Purpose: Patients with rheumatic diseases often have comorbidities that complicate their psychological well-being and affect prognosis. In this study, we looked at 216 patients with…
Abstract Number: 119 • 2015 ACR/ARHP Annual Meeting
Triage in Chronic Rheumatic Diseases: Quantitative Physician Estimates for Inflammation (Reversible), Damage (Irreversible), and Distress in Patients with Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia Seen in Usual Care
Isabel Castrejón¹, Kathryn A. Gibson², Ruchi Jain¹, Annie Huang¹, Joel A. Block³ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Liverpool Hospital, Liverpool, Australia, ³Rush University Medical Center, Chicago, IL
Background/Purpose: A physician estimate of a patient’s global status (DOCGL) often is most often the most efficient of all 7 rheumatoid arthritis (RA) core data…
Abstract Number: 2307 • 2015 ACR/ARHP Annual Meeting
Relationship of Sleep Quality and Fibromyalgia Outcomes in a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study of Bedtime, Rapidly Absorbed, Sublingual Cyclobenzaprine (TNX-102 SL)
Harvey Moldofsky¹, R Michael Gendreau², Daniel J. Clauw³, Judith Gendreau⁴, Benjamin Vaughn⁵, Bruce Daugherty⁴, Amy Forst⁶, Gregory Sullivan⁷ and Seth Lederman⁸, ¹Ctr for Sleep & Chronobiology, Centre for Sleep/Chronobiology, Toronto, ON, Canada, ²Gendreau Consulting LLC, Poway, CA, ³Anesthesiology, University of Michigan, Ann Arbor, MI, ⁴Tonix Pharmaceuticals, New York, NY, ⁵Statistics, Rho, Chapel Hill, NC, ⁶Clinical Development, Tonix Pharmaceuticals, San Jose, CA, ⁷Clinical Development, Tonix Pharmaceuticals, NEW YORK, NY, ⁸Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: The importance of nonrestorative sleep in the pathophysiology of fibromyalgia (FM) suggests that treatments that improve sleep quality would address global symptoms. TNX-102 SL1a…
Abstract Number: 154 • 2015 ACR/ARHP Annual Meeting
Clinical Features of Fibromyalgia in Patients with Rheumatoid Arthritis Predict Lower Power Doppler Scores on Ultrasound
Aneela Mian¹, Khaldoun Chaabo², Julekha Wajed³, Bruce W. Kirkham⁴ and Toby Garrood⁵, ¹Academic Rheumatology, King's College London, London, United Kingdom, ²Rheumatology, Guy's and St Thomas NHS Trust, London, United Kingdom, ³Rheumatology, Guys' and St Thomas' NHS Trust, London, United Kingdom, ⁴Rheumatology, Guy's and St. Thomas' Foundation Hospital NHS Trust, London, United Kingdom, ⁵Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
Background/Purpose: Up to 20% of patients with RA have coexisting fibromyalgia(FM). This can make treatment decisions challenging in clinical practice as disease activity scores can…
Abstract Number: 2308 • 2015 ACR/ARHP Annual Meeting
Responder Compared to Mean Change Analyses in a Fibromyalgia Phase 2b Clinical Study of Bedtime Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL)
R Michael Gendreau¹, Daniel J. Clauw², Judith Gendreau³, Bruce Daugherty³ and Seth Lederman⁴, ¹Gendreau Consulting LLC, Poway, CA, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Tonix Pharmaceuticals, New York, NY, ⁴Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: Fibromyalgia (FM) is characterized by symptoms that include widespread pain and sleep disruption. Clinical studies that rely on patient self-reported outcome measures such as pain…
Abstract Number: 1090 • 2015 ACR/ARHP Annual Meeting
Characteristics and Trajectories of Child Pain, Function, and Psychological Outcomes Associated with Conversion Disorder in Intensive Interdisciplinary Pediatric Pain Rehabilitation
Cara Hoffart¹ and Dustin Wallace², ¹Rheumatology and Integrative Pain Management, Children's Mercy Hospital, Kansas City, MO, ²Integrative Pain Management and Developmental and Behavioral, Children's Mercy Hospital, Kansas City, MO
Background/Purpose: Given the degree of compromise in quality of life, there is a critical need to identify the natural history of pain and disability in…
Abstract Number: 2309 • 2015 ACR/ARHP Annual Meeting
Bedtime, Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL) for the Treatment of Fibromyalgia: Results of a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study
Seth Lederman¹, R Michael Gendreau², Daniel J. Clauw³, Lesley M. Arnold⁴, Judith Gendreau⁵, Bruce Daugherty⁵ and Amy Forst⁶, ¹Research and Development, Tonix Pharmaceuticals, Inc., New York, NY, ²Gendreau Consulting LLC, Poway, CA, ³Anesthesiology, University of Michigan, Ann Arbor, MI, ⁴Psychiatry, University of Cincinnati, Cincinnati, OH, ⁵Tonix Pharmaceuticals, New York, NY, ⁶Clinical Development, Tonix Pharmaceuticals, San Jose, CA
Background/Purpose: Fibromyalgia (FM) is characterized by chronic widespread pain and sleep disturbance. Treatments that improve sleep quality in FM patients may improve fibromyalgia by a…
Abstract Number: 1091 • 2015 ACR/ARHP Annual Meeting
Effectiveness of Multidisciplinary Pain Rehabilitation Programs for Patients with Fibromyalgia Syndrome: A Systematic Review
Niall Halliday^1,2, Caroline Treanor², Rose Galvin³ and Jason Brooks⁴, ¹Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast, Northern Ireland, ²Physiotherapy, Beaumont Hospital, Dublin, Ireland, ³Clinical Therapies, University of Limerick, Limerick, Ireland, ⁴Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast, Ireland
Background/Purpose: Fibromyalgia syndrome (FMS) is a common, chronic pain condition with complex multiple symptoms. Combinations of therapies in a multidisciplinary pain rehabilitation program (MPRP) are…
Abstract Number: 2310 • 2015 ACR/ARHP Annual Meeting
Evaluation of Fibromyalgia Syndrome in Patients Undergoing Peritoneal Dialysis
Taskin Senturk¹, Gokhan Sargin² and Hakan Akdam³, ¹Rheumatology, Adnan Menderes University School of Medicine, Aydin, Turkey, ²Rheumatology, Adnan Menderes University Rheumatology, Aydin, Turkey, ³Nephrology, Adnan Menderes University, Nephrology, Aydin, Turkey
Background/Purpose: Fibromyalgia syndrome (FMS) is characterized by widespread pain, fatigue, memory problems. The syndrome is present in about %2-8 of general population. However, knowledge about this…
Abstract Number: 1427 • 2015 ACR/ARHP Annual Meeting
Analgesic Effects of the Novel Alpha-2-Delta Ligand Mirogabalin (DS-5565) in Experimental Animal Models of Fibromyalgia
Yuki Domon¹, Naohisa Arakawa¹, Shun-ichi Yasuda², Kensuke Saeki², Mayumi Kano², Masami Kato² and Yutaka Kitano¹, ¹Biological Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan, ²Hashima Laboratory, Nihon Bioresearch Inc., Gifu, Japan
Background/Purpose: Mirogabalin (DS-5565) is a novel ligand of the α2δ subunit of voltage-gated calcium channels. Mirogabalin possesses unique binding characteristics to α2δ subunits, and potent…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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