fibroblasts and skin Archives - ACR Meeting Abstracts

Abstract Number: 1851 • ACR/ARHP Annual Meeting 2013
Adenosine 2A Receptor Promotes Collagen Production By Human Fibroblasts Via Smad2/3-Independent Pathways Involving Cyclic AMP and AKT
Miguel Perez-Aso¹, Patricia Fernandez², Aranzazu Mediero³, Edwin SL Chan⁴ and Bruce N. Cronstein⁵, ¹Department of Translational Medicine, New York University School of Medicine, New York, NY, ²Medicine, National Cancer Institute, NIH, Bethesda, MD, ³Medicine, Division of Translational Medicine, NYU School of Medicine, New York, NY, ⁴Medicine, New York University School of Medicine, New York, NY, ⁵Internal Medicine, NYU School of Medicine, Division of Rheumatology, New York, NY
Background/Purpose: Activation of Adenosine 2A Receptors (A2AR) promotes fibrosis and collagen synthesis. However, the underlying mechanism by which A2AR stimulate collagen synthesis is still unclear. …

Abstracts tagged "fibroblasts and skin"