Abstracts tagged "fibroblasts and matrix metalloproteinase (MMP)"

Abstract Number: 892 • 2012 ACR/ARHP Annual Meeting
The Epigenetically Repressed Long Noncoding RNA Hotair Influences the Expression of Matrix Metalloproteases in Synovial Fibroblasts
Michelle Trenkmann¹, Matthias Brock², Renate E. Gay³, Beat A. Michel⁴, Lars C. Huber² and Steffen Gay³, ¹Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland, ²Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland, ³Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland
Background/Purpose: Long noncoding RNAs (lncRNA, >200nt) have recently emerged as regulators of gene expression functioning as signals, decoys, guides or scaffolds for transcription factors and/or…

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Abstracts tagged "fibroblasts and matrix metalloproteinase (MMP)"

The Epigenetically Repressed Long Noncoding RNA Hotair Influences the Expression of Matrix Metalloproteases in Synovial Fibroblasts