Abstracts tagged "fibroblast-ilke synoviocytes and somatic mutations"

Abstract Number: 2011 • 2019 ACR/ARP Annual Meeting
Novel Somatic Mutations Identified by Whole Genome Sequencing of Rheumatoid Arthritis (RA) Fibroblast-Like Synoviocytes (FLS)
Richard Ainsworth ¹, Deepa Hammaker ², David Boyle ¹, Rizi Ai², Jeremy Sokolove ³, Wei Wang ¹ and Gary Firestein ², ¹University of California, San Diego, San Diego, CA, ²University of California, San Diego, San Diego, ³AbbVie Immunology Clinical Development, Redwood City
Background/Purpose: Somatic mutations caused by reactive oxygen and nitrogen species in inflamed joints, have been implicated in the destructive nature of RA. Mutation analysis also…

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Abstracts tagged "fibroblast-ilke synoviocytes and somatic mutations"

Novel Somatic Mutations Identified by Whole Genome Sequencing of Rheumatoid Arthritis (RA) Fibroblast-Like Synoviocytes (FLS)