Abstracts tagged "Fever and tumor necrosis factor (TNF)"

Abstract Number: 749 • 2012 ACR/ARHP Annual Meeting
Efficacy and Safety of Canakinumab in Patients with TNF Receptor Associated Periodic Syndrome
Marco Gattorno¹, Laura Obici², Antonella Meini³, Vincent Tormey⁴, Ken Abrams⁵, Nicole Davis⁵, Christopher Andrews⁶ and Helen J. Lachmann⁷, ¹Second Division of Paediatrics, Istituto Giannina Gaslini, Genova, Italy, ²Amyloid Centre, IRCCS Policlinico San Matteo, Pavia, Italy, ³Pediatric Clinic, University of Brescia and Spedali Civili di Brescia, Pediatric Immunology and Rheumatology, Brescia, Italy, ⁴Galway University Hospitals, Galway, Ireland, ⁵Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁶Novartis Pharmaceuticals UK Limited, Surrey, United Kingdom, ⁷UK National Amyloidosis Centre, University College London Medical School, London, United Kingdom
Background/Purpose: TNF-receptor associated periodic syndrome (TRAPS) is a rare dominantly inherited periodic fever syndrome due to mutations of the TNFRSF1A gene. It is characterized by…

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