Abstracts tagged "Fatigue"

Abstract Number: 1314 • ACR Convergence 2020
Fatigue in Psoriatic Arthritis (PsA): Prevalence in Patients from the US and Europe, and Impact on Quality of Life and Work Productivity
Jessica Walsh¹, Kaleb Michaud², Elizabeth Holdsworth³, Steven Peterson⁴, Nicola Booth³, Sophie Meakin³, Soumya Chakravarty⁵, James Piercy³ and Alexis Ogdie⁶, ¹University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, ²University of Nebraska Medical Center, Omaha, NE, ³Adelphi Real World, Bollington, United Kingdom, ⁴Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, ⁵Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, ⁶Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Fatigue is an important aspect of PsA for patients. Understanding the impact of fatigue on patient reported outcomes is important for effective management of…
Abstract Number: 1315 • ACR Convergence 2020
Exploring the Prevalence and Factors Associated with Fatigue in Axial Spondyloarthritis in a Multiethnic Asian Cohort in Singapore
Wei Ze Lim¹, Warren Fong², Yu Heng Kwan³ and Ying Ying Leung², ¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Singapore, ²Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, Singapore, ³Duke-NUS Medical School, Singapore, Singapore, Singapore
Background/Purpose: Fatigue is a cardinal symptom of axial spondyloarthritis (axSpA) that poses management challenges. Data on fatigue amongst Asian patients with axSpA is limited. Ethnicity…
Abstract Number: 0134 • ACR Convergence 2020
The Impact of Exercise on Sleep in People with Rheumatoid Arthritis: A Pilot Randomised Controlled Trial
Sean McKenna¹, Laura Comber², Alan Donnelly³, Alexander Fraser⁴, Bente Appel Esbensen⁵ and Norelee Kennedy³, ¹University of Limerick, Mallow, Cork, Ireland, ²HIQA, Limerick, Limerick, Ireland, ³University of Limerick, Limerick, Limerick, Ireland, ⁴University College Limerick, Limerick, Limerick, Ireland, ⁵University of Copenhagen, Glostrup, Hovedstaden, Denmark
Background/Purpose: Poor sleep quality and reduced sleep duration are prevalent complaints in people with RA. These in turn may further deteriorate functional ability and reduce…
Abstract Number: 1340 • ACR Convergence 2020
Secukinumab Improves Pain, Morning Stiffness, Fatigue and Physical Function in Tumor Necrosis Factor Inhibitor-Naïve Patients with Non-Radiographic Axial Spondyloarthritis: Results from a Randomized Controlled Phase III Study
Helena Marzo-Ortega¹, Atul Deodhar², Ricardo Blanco³, Hideto Kameda⁴, Alan Kivitz⁵, Denis Poddubnyy⁶, Marina Magrey⁷, Jianyuan Wang⁸, Sibylle Haemmerle⁸, Abhijit Shete⁸ and Juergen Braun⁹, ¹The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, United Kingdom, ²Oregon Health & Science University, Portland, OR, ³Hospital University Marqués de Valdecilla, Santander, Spain, ⁴Toho University, Tokyo, Japan, ⁵Altoona Center for Clinical Research/Altoona Arthritis and Osteoporosis Center, Duncansville, PA, ⁶Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁷Case Western Reserve University School of Medicine, Cleveland, OH, ⁸Novartis Pharma AG, Basel, Switzerland, ⁹Rheumazentrum Ruhrgebiet and Ruhr-University, 44649 Herne, Germany
Background/Purpose: Patients with non-radiographic axial spondyloarthritis (nr-axSpA) suffer from comparable disease burden to patients with ankylosing spondylitis/radiographic axSpA (AS/r-axSpA), including inflammatory back pain, morning stiffness,…
Abstract Number: 148 • 2020 Pediatric Rheumatology Symposium
Chronic Fatigue Symptoms in Children with Abrupt Early-onset OCD And/or PANS
Avis Chan ¹, Angeline Truong ², Bahare Farhadian ³, Theresa Willett ², Melissa Silverman ¹, Paula Tran ¹, Margo Thienemann ² and Jennifer Frankovich⁴, ¹Stanford University School of Medicine, Palo Alto, ²Stanford University School of Medicine, Palo Alto, California, ³Stanford Immune Behavioral Health Clinic and PANS Research Program at Lucile Packard Children's Hospital, Palo Alto, ⁴Stanford
Background/Purpose: Chronic Fatigue Syndrome (CFS)/Myalgic encephalomyelitis (ME) affects roughly 2.5 million people in the United States, and is challenging both in diagnosis and treatment. Many…
Abstract Number: 417 • 2019 ACR/ARP Annual Meeting
Contribution of Pain Relief to Function, Fatigue, and Quality of Life When Inflammation Is Controlled in Patients with Rheumatoid Arthritis
Mart A.F.J. van de Laar¹, Janet Pope ², Yvonne Lee ³, Bruno Fautrel ⁴, Kei Ikeda ⁵, Amanda Quebe ⁶, Xiang Zhang ⁶, Carol Gaich ⁶, Francesco De Leonardis ⁶, Jeffrey Lisse ⁶, Jennifer Workman ⁶, Roy Fleischmann ⁷, Mark Genovese ⁸ and Peter Taylor ⁹, ¹Arthritis Center Twente, Enschede, Netherlands, ²Western University, London, ON, Canada, ³Northwestern University Feinberg School of Medicine, Chicago, ⁴Pitié-Salpêtrière Hospital, Department of Rheumatology, AP-HP, Sorbonne University, UPMC university, Paris, Ile-de-France, France, ⁵Chiba University Hospital, Chiba, Japan, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, ⁸Stanford University, Stanford, CA, ⁹University of Oxford, Oxford, United Kingdom
Background/Purpose: Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, has shown clinical efficacy and patient-reported pain relief in patients (pts) with RA and…
Abstract Number: 470 • 2019 ACR/ARP Annual Meeting
Obesity Is a Robust Predictor of Persistent High Fatigue at 1 Year in Women and Men with Early Rheumatoid Arthritis
Susan J. Bartlett¹, Orit Schieir ², Marie-France Valois ³, Janet Pope ⁴, Louis Bessette ⁵, Carol Hitchon ⁶, Carter Thorne ⁷, Diane Tin ⁸, Glen Hazlewood ⁹, Gilles Boire ¹⁰, Edward Keystone ¹¹, Vivian Bykerk ¹² and Canadian Early Arthritis Cohort (CATCH) Investigators ¹³, ¹McGill University, Montreal, QC, Canada, ²University of Toronto, Montreal, Canada, ³McGill University, Montreal, Canada, ⁴Western University, London, ON, Canada, ⁵Laval University, Quebec City, QC, Canada, ⁶University of Manitoba, Winnipeg, Canada, ⁷Southlake Regional Health Centre, Newmarket, ON, Canada, ⁸Southlake Regional Health Centre, Newmarket, Canada, ⁹University of Calgary, Calgary, Canada, ¹⁰Sherbrooke University, Sherbrooke, QC, Canada, ¹¹Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada, ¹²Hospital for Special Surgery, New York City, NY, ¹³Canadian Early Arthritis Cohort (CATCH) Study, Toronto, Canada
Background/Purpose: While treat-to-target strategies can dramatically reduce inflammation in RA, persistently high levels of fatigue are present in many patients and represent an important unmet need.…
Abstract Number: 471 • 2019 ACR/ARP Annual Meeting
When Will I Get past This Exhaustion? Predictors of Improved Fatigue in the First Year of RA
Susan J. Bartlett¹, Orit Schieir ², Marie-France Valois ³, Carol Hitchon ⁴, Louis Bessette ⁵, Glen Hazlewood ⁶, Carter Thorne ⁷, Janet Pope ⁸, Gilles Boire ⁹, Diane Tin ¹⁰, Edward Keystone ¹¹, Vivian Bykerk ¹² and Canadian Early Arthritis Cohort (CATCH) Investigators ¹³, ¹McGill University, Montreal, QC, Canada, ²University of Toronto, Montreal, Canada, ³McGill University, Montreal, Canada, ⁴University of Manitoba, Winnipeg, Canada, ⁵Laval University, Quebec City, QC, Canada, ⁶University of Calgary, Calgary, Canada, ⁷Southlake Regional Health Centre, Newmarket, ON, Canada, ⁸Western University, London, ON, Canada, ⁹Sherbrooke University, Sherbrooke, QC, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, Canada, ¹¹Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada, ¹²Hospital for Special Surgery, New York City, NY, ¹³Canadian Early Arthritis Cohort (CATCH) Study, Toronto, Canada
Background/Purpose: Although overwhelming fatigue is common at the onset of RA, some patients continue to experience debilitating high levels of fatigue that impact mood, interfere with work…
Abstract Number: 649 • 2019 ACR/ARP Annual Meeting
Potentially Reversible Associations with Fatigue in SLE Patients – Results from a Single-centre Study
Christina Duesing¹, Gamal Chehab ², Jutta Richter ³, Oliver Sander ⁴, Rebecca Fischer-Betz ⁵, Benedikt Ostendorf ¹, Hasan Acar ¹, Ralph Brinks ⁶ and Matthias Schneider ⁵, ¹Policlinic of Rheumatology and Hiller Research Unit Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, Duesseldorf, Nordrhein-Westfalen, Germany, ²Policlinic of Rheumatology and Hiller Research Unit Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, ³Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, ⁴Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, ⁵Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany, ⁶Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
Background/Purpose: Fatigue is the most common symptom in SLE patients with a strong impact on patients’ reported quality of life. The cause of fatigue is…
Abstract Number: 679 • 2019 ACR/ARP Annual Meeting
Longitudinal Changes in Manifestations of SLE
Amanda Eudy¹, Jennifer Rogers ¹, Raeann Whitney ¹, Lisa Criscione-Schreiber ¹, Jayanth Doss ¹, David Pisetsky ², Rebecca Sadun ¹, Kai Sun ¹ and Megan Clowse ¹, ¹Duke University, Durham, ²Duke University, Durham VAMC, Durham
Background/Purpose: Our group has developed a conceptual model to categorize SLE manifestations into two dimensions termed Type 1 and Type 2. Type 1 SLE consists…
Abstract Number: 1334 • 2019 ACR/ARP Annual Meeting
Patterns of Fatigue in Rheumatoid Arthritis Patients Who Received Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs
Dalifer Freites Nuñez¹, Leticia León ², Marta Redondo ³, Cristina Vadillo Font ⁴, Pia Lois ⁵, Arkaitz Mucientes Ruiz ⁴, Luis Rodríguez-Rodríguez ⁶, Benjamín Fernández Gutiérrez ⁷, Juan Angel Jover Jover ⁴ and lydia Abasolo Alcazar ⁴, ¹Hospital Clínico San Carlos, MADRID, Spain, ²Fundación para la Investigación Biomedica, Madrid, Madrid, Spain, ³Universidad Camilo José Ceja, Madrid, Madrid, Spain, ⁴HOSPITAL CLINICO SAN CARLOS, MADRID, Spain, ⁵Hospital Clínico San Carlos, Madrid, Madrid, Spain, ⁶Fundación para la Investigación Biomedica, Madrid, Spain, ⁷Hospital Clínico San Carlos, Madrid
Background/Purpose: Fatigue is one of the most frequent symptoms in patients with rheumatoid arthritis (RA), affecting more than 80% of them. The experience of fatigue…
Abstract Number: 1337 • 2019 ACR/ARP Annual Meeting
Fatigue Levels Are Not Associated with Inflammatory Activity, but with Subjective Outcomes: Results from a Longitudinal Study of Patients with Rheumatoid Arthritis Initiating bDMARD Therapy
Hilde Hammer¹, Brigitte Michelsen ², Joe Sexton ³, Sella Provan ¹, Till Uhlig ⁴ and Tore Kvien ⁴, ¹Diakonhjemmet Hospital, Oslo, Norway, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark/ Hospital of Southern Norway Trust, Kristiansand, Norway/ Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, ³Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway, ⁴Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway
Background/Purpose: Fatigue is a sensation of weakness and lack of energy which is common in patients with rheumatoid arthritis (RA), contributing to reduced quality of…
Abstract Number: 1595 • 2019 ACR/ARP Annual Meeting
Role of Aerobic Exercise in Modulating Fatigue in Women with Systemic Lupus Erythematosus
Marquis Chapman ¹, Sarthak Gupta², Jun Chu ¹, Mohammad Naqi ³, Zerai Manna ³, Mir Ali Mazhar ¹, Adam Munday ¹, Marybeth Stockman ⁴, Bart Dinkard ⁴, Lisa Chin ⁴, Mariana Kaplan ¹, Randall Keyser ⁵, Leighton Chan ⁴ and Sarfaraz Hasni ⁶, ¹National Institute of Arthritis, Musculoskeletal, and Skin diseases/ National Institutes of Health, Bethesda, ²Systemic Autoimmunity Branch, NIAMS, NIH, Bethesda, ³NIAMS/NIH, Bethesda, ⁴Rehabilitation Medicine Department, Clinical Center, NIH, Bethesda, ⁵Department of Rehabilitation Science, George Mason University, Bethesda, ⁶National Institute of Arthritis, Musculoskeletal, and Skin diseases/ National Institutes of Health, Bethesda, MD
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that predominantly afflicts women. One of the most debilitating symptoms experienced by SLE patients is…
Abstract Number: 2069 • 2019 ACR/ARP Annual Meeting
Alcohol Consumption Is Not an Independent Predictor of Fatigue Severity over Time
Katie Druce¹, Belay Yimer ¹, Lis Cordingley ², Mark Lunt ¹, Simon Kyle ³, Will Dixon ⁴ and John McBeth ⁴, ¹Versus Arthritis Centre for Epidemiology, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, Manchester, ²Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, Manchester, ³Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK, Oxford, ⁴Versus Arthritis Centre for Epidemiology, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, Manchester, United Kingdom
Background/Purpose: Alcohol consumption is a common, but declining, lifestyle behaviour of UK adults. Previous research has shown that among people with rheumatoid arthritis (RA) moderate…
Abstract Number: 2433 • 2019 ACR/ARP Annual Meeting
Fatigue in Primary Sjögren’s Syndrome as a Manifestation of Heavier Disease Activity of Mucosa-Associated Lymphoid Tissue (MALT)
Saviana Gandolfo¹, Marco Binutti ¹, Elena Doriguzzi Breatta ¹, Cinzia Fabro ¹ and Salvatore De Vita ¹, ¹Rheumatology Clinic, Udine University Hospital, Department of Medical Area, University of Udine, Udine, Italy, Udine, Italy
Background/Purpose: Fatigue is one of the most prevalent and impacting symptoms in primary Sjögren’s syndrome (pSS), significantly impairing the patient quality of life. To date,…

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