Abstracts tagged "Fatigue"

Abstract Number: 2475 • 2018 ACR/ARHP Annual Meeting
Promis Pain Interference 6b and Fatigue 7a Short Forms and Profile-29 in Rheumatoid Arthritis Patients Treated with TNF Inhibitors
Clifton O. Bingham III¹, Sergio Schwartzman², Shelly Kafka³, Dennis Parenti³, Shawn Black³, Stephen Xu⁴, Wayne Langholff⁴ and Jeffrey R. Curtis⁵, ¹Johns Hopkins University, Baltimore, PA, ²Weill Cornell Medical College, New York, NY, ³Janssen Scientific Affairs, LLC, Horsham, PA, ⁴Janssen Research & Development, LLC, Spring House, PA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: PROMIS (Patient Reported Outcomes Measurement Information System) has been used in rheumatoid arthritis (RA) patients (Pts) to assess disease activity across multiple domains (i.e.…
Abstract Number: 2552 • 2018 ACR/ARHP Annual Meeting
Fatigue in Psoriatic Arthritis Patients Treated with Intravenous Golimumab: Early Improvement Is Associated with Week 24 Outcomes in Acr 20, 50, and Health-Related Quality of Life
Arthur Kavanaugh¹, M. Elaine Husni², Eric K. H. Chan³, Diane D. Harrison⁴, Lilianne Kim⁴, Kim Hung Lo⁴, Elizabeth C Hsia⁵ and Chenglong Han⁶, ¹University of California, San Diego, School of Medicine, La Jolla, CA, ²Orthopedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, ³Janssen Global Services, LLC, Raritan, NJ, ⁴Janssen Research & Development, LLC, Spring House, PA, ⁵Janssen Research & Development, LLC/University of Pennsylvania, Spring House/Philadelphia, PA, ⁶Janssen Global Services, LLC, Malvern, PA
Background/Purpose: To investigate improvement in fatigue in adult patients with active psoriatic arthritis (PsA) treated with intravenously administered (IV) golimumab, an anti-TNFα…
Abstract Number: 2561 • 2018 ACR/ARHP Annual Meeting
Rapid and Sustained Improvements in Patient-Reported Signs and Symptoms with Ixekizumab in Biologic-Naive and TNF-Inadequate Responder Patients with Psoriatic Arthritis
Ana-Maria Orbai¹, Dafna D Gladman², Julie Birt³, Amanda M. Gellett³, Chen-Yen Lin³ and Tore Kvien⁴, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Toronto, Toronto, ON, Canada, ³Eli Lilly and Company, Indianapolis, IN, ⁴Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Ixekizumab (IXE), a high-affinity mAb that selectively targets IL-17A, has shown improvements up to Week (Wk) 24 across several domains of PsA (including ACR20)…
Abstract Number: 2652 • 2018 ACR/ARHP Annual Meeting
Engaging the Cholinergic Anti-Inflammatory Pathway By Stimulating the Vagus Nerve Reduces Pain and Fatigue in Patients with SLE
Cynthia Aranow¹, Martin Lesser², Meggan Mackay¹, Erik Anderson³, Theodoros P. Zanos², Timir Datta-Chaudhuri², Chad Bouton², Kevin J. Tracey⁴ and Betty Diamond¹, ¹The Feinstein Institute for Medical Research, Manhasset, NY, ²Feinstein Institute for Medical Research, Manhasset, NY, ³Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research, Manhasset, NY, ⁴Laboratory of Biomedical Science, Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Musculoskeletal (MS) pain is a common symptom of patients with Systemic Lupus Erythematosus (SLE) affecting up to 95% of patients and contributing to…
Abstract Number: 1387 • 2018 ACR/ARHP Annual Meeting
Fatigue in Patients with Rheumatoid Arthritis As Compared to Different Groups of Cancer Patients
Jens Gert Kuipers¹, Michael Koller², Ulrich Rueffer³, Florian Zeman², Karolina Mueller⁴ and Joachim Weis⁵, ¹Clinic for Internal Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, ²Center of Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ³German Fatigue Society, Cologne, Germany, ⁴Center for Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ⁵University Clinic Centre Freiburg, Freiburg, Germany
Background/Purpose: Fatigue is a common symptom in patients with rheumatoid arthritis (RA) as well as patients with cancer. Fatigue considerably reduces the quality of life…
Abstract Number: 158 • 2017 ACR/ARHP Annual Meeting
Is Lu Eight-Brocades Exercise Beneficial for Patients with Fibromyalgia?
Juan Jiao¹, Irwin Jon Russell², Wen Wang³, Ya-yun Zhao⁴, Rou-man Zhang⁴, Jing Wang⁴ and Quan Jiang⁵, ¹Rheumatism Department, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China, ²Affiliated with Arthritis & Osteoporosis Center of South Texas, Medical Director, Fibromyalgia Research and Consulting, San Antonio, Texas, San Antonio, TX, ³JCW Education Consulting, Conway, AR, ⁴Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China, ⁵Rheumatology Department, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China
Background/Purpose: Fibromyalgia is a chronic debilitating musculoskeletal pain syndrome that causes substantial physical and psychological impairments. With the release of the 2016 revised EULAR recommendations…
Abstract Number: 463 • 2017 ACR/ARHP Annual Meeting
Certolizumab Pegol for Fatigue in Chronic Inflammatory Rheumatic Diseases: A Meta-Analysis
Yesim Ozguler¹, Sinem Nihal Esatoglu¹, Guzin Karatemiz¹, Ali Ugur Unal², Gul Guzelant¹, Elif Dincses³, Mustafa Erdogan¹, Sema Kaymaz Tahra² and Gulen Hatemi¹, ¹Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²Departement of Internal Medicine, Division of Rheumatology, Marmara University, Istanbul, Turkey, ³Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, İstanbul, Turkey
Background/Purpose: Fatigue is an important problem that impairs life quality in patients with rheumatic diseases. Although fatigue is often associated with disease activity, only a…
Abstract Number: 1235 • 2017 ACR/ARHP Annual Meeting
Perceived Stress and Fatigue in Systemic Lupus Erythematosus
Patricia P. Katz¹, Desiree R Azizoddin² and Meenakshi Jolly³, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²Department of Medicine and Behavioral Sciences, Rush University, Chicago, IL, ³Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Fatigue is a common and often severe symptom among individuals with systemic lupus erythematosus (SLE). Yet, there is an incomplete understanding of the causes…
Abstract Number: 1354 • 2017 ACR/ARHP Annual Meeting
Fatigue, Poor Health and Mood Disturbance Persist in Rheumatoid Arthritis and Psoriatic Arthritis Patients Despite Disease Remission: The OPAL Deeper Study
Paul Bird¹, Hedley Griffiths², Geoff Littlejohn³, Peter Youssef⁴, Fred Joshua⁵, Peter Nash⁶, Julien De Jager⁷, Tegan Smith⁸, Janet Sanburg⁹ and Kathleen Tymms¹⁰, ¹University of New South Wales, Sydney, Australia, ²Barwon Rheumatology Service, Geelong, Australia, ³Medicine, Monash, Melbourne, Australia, ⁴Royal Prince Alfred Hospital, Camperdown, Sydney, Australia, ⁵Combined Rheumatology Practice, Sydney, NSW, Australia, ⁶University of Queensland, Brisbane, Australia, ⁷University Of Queensland, Southport, Australia, ⁸OPAL, Sydney, Australia, ⁹OPAL, Melbourne, Australia, ¹⁰ANU, Canberra, Australia
Background/Purpose: Patient reported outcomes are recognized as increasingly important in defining the full burden of disease experienced by patients with rheumatic disease. Traditional measures of…
Abstract Number: 1388 • 2017 ACR/ARHP Annual Meeting
Fatigue Is Strongly Associated with the Patient Global Assessment and May Affect Disease Severity and Clinical Remission in Patients with Rheumatoid Arthritis: A Cross-Sectional Study from IORRA, a Large Observational Cohort of Japanese Rheumatoid Arthritis Patients
Naoki Sugimoto¹, Eiichi Tanaka¹, Eisuke Inoue^1,2, Kumiko Saka¹, Eri Sugano¹, Naohiro Sugitani¹, Moeko Ochiai¹, Yoko Shimizu¹, Rei Yamaguchi¹, Katsunori Ikari¹, Ayako Nakajima¹, Atsuo Taniguchi¹ and Hisashi Yamanaka¹, ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Fatigue is a common complaint in patients with rheumatoid arthritis (RA)1. However, its impact on disease activity and clinical remission in patients with RA…
Abstract Number: 1500 • 2017 ACR/ARHP Annual Meeting
Longitudinal Analysis of Different Therapeutic Strategies in Patients with Primary Sjögren’s Syndrome
Kristen Davies¹, Kamran Mirza¹, Jessica Tarn², Marian Regan³, Saravanan Vadivelu⁴, Gavin Clunie⁵, Jacqueline Andrews⁶, Elizabeth Price⁷, Steve Young-Min⁸, Ian Giles⁹, Bhaskar Dasgupta¹⁰, Cathy Lawson¹¹, Nagui Gendi¹², Neil J. McHugh¹³, Michele Bombardieri¹⁴, Costantino Pitzalis¹⁴, Nurhan Sutcliffe¹⁴, Simon Bowman¹⁵, Dennis Lendrem^16,17 and Wan-Fai Ng^2,18, ¹Institute of Cellular Medicine, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom, ²Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom, ³Royal Derby Hospital, Derby, UK, Derby, United Kingdom, ⁴Queen Elizabeth Hospital, Gateshead, UK, Gateshead, United Kingdom, ⁵Ipswich Hospital NHS Trust, Ipswich, UK, Ipswich, United Kingdom, ⁶Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom, ⁷Great Western Hospital, Swindon, UK, Swindon, United Kingdom, ⁸Queen Alexander Hospital, Portsmouth, UK, Portsmouth, United Kingdom, ⁹Centre for Rheumatology, University College London, Centre for Rheumatology, University College London, UK, London, United Kingdom, ¹⁰Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, Westcliff-on-Sea, United Kingdom, ¹¹Harrogate District Hospital, Harrogate, UK, Harrogate, United Kingdom, ¹²Basildon and Thurrock University Hospital, Basildon, UK, Basildon, United Kingdom, ¹³Royal National Hospital for Rheumatic Diseases, Bath, UK, Bath, United Kingdom, ¹⁴Barts Health NHS Trust & Barts and the London School of Medicine & Dentistry, London, UK, London, United Kingdom, ¹⁵Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, Birmingham, United Kingdom, ¹⁶Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-upon-Tyne, United Kingdom, ¹⁷Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK, Newcastle, United Kingdom, ¹⁸Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease characterised by sicca features and systemic manifestations such as pain and fatigue. The classic…
Abstract Number: 1528 • 2017 ACR/ARHP Annual Meeting
Secukinumab Provides Rapid and Sustained Pain Relief in Ankylosing Spondylitis Patients with Normal or Elevated Baseline CRP Levels and Correlated with Improvement in Fatigue
Atul A. Deodhar¹, Philip G. Conaghan², Tore K Kvien³, Vibeke Strand⁴, Lawrence Rasouliyan⁵, Brian Porter⁶, Steffen Jugl⁷ and Kunal Gandhi⁶, ¹Oregon Health & Science University, Portland, OR, ²University of Leeds, Leeds, United Kingdom, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴Stanford University School of Medicine, Palo Alto, CA, ⁵RTI Health Solutions, Barcelona, Spain, ⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁷Novartis Pharma AG, Basel, Switzerland
Background/Purpose: Secukinumab has demonstrated sustained efficacy in patients (pts) with active AS.1,2 We investigated improvement in pain and fatigue scores from baseline (BL) through Week…
Abstract Number: 1602 • 2017 ACR/ARHP Annual Meeting
Fatigue in Systemic Lupus: The Role of Disease Activity and Its Mediators
Desiree R Azizoddin¹, Meenakshi Jolly², Joel A. Block³ and Perry M. Nicassio⁴, ¹Department of Medicine and Behavioral Sciences, Rush University, Chicago, IL, ²Rush, Chicago, IL, ³Division of Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Cousins Center for PNI, UCLA, LA, CA
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that leads to a variety of negative health outcomes. Though treatment continues to advance, fatigue…
Abstract Number: 2254 • 2017 ACR/ARHP Annual Meeting
Disability (HAQ) and Quality of Life (SF-12) As Related to Adherence and Health Literacyin Patients with Rheumatoid Arthritis – the Trace-Study
Jens Gert Kuipers¹, Michael Koller², Florian Zeman², Karolina Mueller² and Jens Ulrich Rueffer³, ¹Department of Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, ²University Hospital Regensburg, Center for Clinical Studies, Regensburg, Germany, ³German Fatigue Society, Cologne, Germany
Background/Purpose: Disabilities in daily living and quality of life are key endpoints to evaluate the outcome of treatment for rheumatoid arthritis (RA). Among factors that…
Abstract Number: 2538 • 2017 ACR/ARHP Annual Meeting
Change in Self-Reported Health Status and Fatigue before and after the Diagnosis of Psoriatic Arthritis- the Nord-Trondelag Health Study (HUNT)
Mari Hoff¹, Tom Ivar Lund Nilsen², Ruth Stoklund Thomsen³, Agnete Malm Gulati⁴, Arthur Kavanaugh⁵ and Glenn Haugeberg⁴, ¹Rheumatolgy, University Hospital, St. Olavs Hospital, NTNU, Trondheim, Norway, ²Faculty of medicine, Department of public health and nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway, ³Faculty of Medicine, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway, ⁴NTNU, Norwegian University of Science and Technology, Trondheim, Norway, ⁵Medicine, University of California, San Diego, La Jolla, CA
Background/Purpose: Psoriatic arthritis (PsA) is a systemic inflammatory disease that can involve skin, nails, joints, enthuses, and can be associated with systemic symptoms such as…

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