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Abstracts tagged "family studies"

  • Abstract Number: 117 • 2020 Pediatric Rheumatology Symposium

    Family Impact of Juvenile Localized Scleroderma

    Katia Milovanova1, Vimal Prajapati 2, Merna Adly 2, Rebeka Stevenson 3, Brendan Lethebe 2 and Nadia Luca 2, 1University of Alberta, Edmonton, Alberta, Canada, 2University of Calgary, Calgary, Alberta, Canada, 3Cochrane, Alberta, Canada

    Background/Purpose: Juvenile localized scleroderma (jLS) is a rare autoimmune disease that can lead to significant morbidity. Previous studies have focused on predictors of patient health-related…
  • Abstract Number: 147 • 2020 Pediatric Rheumatology Symposium

    Familial Clustering of Immune-mediated Diseases in Children with Abrupt-onset OCD

    Avis Chan 1, Tiffany Phu 1, Bahare Farhadian 2, Theresa Willett 3, Melissa Silverman 1, Paula Tran 1, Margo Thienemann 3 and Jennifer Frankovich4, 1Stanford University School of Medicine, Palo Alto, 2Stanford Immune Behavioral Health Clinic and PANS Research Program at Lucile Packard Children's Hospital, Palo Alto, 3Stanford University School of Medicine, Palo Alto, California, 4Stanford

    Background/Purpose: Recent epidemiologic studies have reported increased rates of immune-mediated comorbidities among first-degree relatives of patients with OCD and tic disorders.(Mataix-Cols et al., Mol Psychiatry…
  • Abstract Number: 1104 • 2019 ACR/ARP Annual Meeting

    Heritability and Familial Risk of Systemic Lupus Erythematosus in Sweden: A Population-based Case-control Study

    Elizabeth Arkema1, Marios Rossides 1, Christopher Sjöwall 2, Elisabet Svenungsson 3 and Julia Simard 4, 1Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, 2Department of Clinical and Experimental Medicine, Rheumatology/Division of Neuro and Inflammation Sciences, Linköping University, Linköping, Sweden, 3Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, 4Stanford University School of Medicine, Palo Alto, CA

    Background/Purpose: Previous studies examining the relative risk (RR) associated with having a first degree relative (FDR) with systemic lupus erythematosus (SLE) were small and few…
  • Abstract Number: 2186 • 2018 ACR/ARHP Annual Meeting

    Process Evaluation of a Culturally-Sensitive, Community Based Self-Management Program for First Nations People with Arthritis and Their Families

    Diane Lacaille1, June Kaminski2, Jade Collison3, Linda Lavender4, Monica Brown5, Kim Roberts6, Deborah Da Costa7, Paul Adam8, Linda Li2 and Allen Lehman9, 1Arthritis Research Canada/University of British Columbia, Medicine/Rheumatology, Richmond, BC, Canada, 2Arthritis Research Canada, Richmond, BC, Canada, 3Haida Health Centre, Old Massett, BC, Canada, 4Kwakiutl District Council Health Services, Campbell River, BC, Canada, 5Director, Haida Health Centre, Old Massett, BC, Canada, 6Director, Kwakiutl District Council Health Services, Campbell River, BC, Canada, 7Medicine, McGill University, Montreal, QC, Canada, 8Mary Pack Arthritis Program, Vancouver, BC, Canada, 9Senior Medical Scientific Liaison-Rheumatology, Janssen, Pharmaceutical Companies of Johnson and Johnson, Vancouver, BC, Canada

    Background/Purpose: First Nation community consultations identified arthritis as a priority health concern and the need for culturally sensitive health services adapted to community needs. In…
  • Abstract Number: 1308 • 2017 ACR/ARHP Annual Meeting

    Answering Reproductive Health Questions That Your Patients Want to Know: Impediments to Family Building and Risks of Contraception

    Malithi Jayasundara1, Amanda M. Eudy2, Tayseer Haroun3, W. Benjamin Nowell4, Jeffrey R. Curtis5, Rachelle Crow-Hercher6, Charlotte Whitney White6, Seth D. Ginsberg7 and Megan E. B. Clowse8, 1Rheumatology, Duke University, Durham, NC, 2Duke University, Durham, NC, 3Department of Medicine/Division of Rheumatology, Duke University Medical Center, Durham, NC, 4Global Healthy Living Foundation, Upper Nyack, NY, 5University of Alabama at Birmingham, Birmingham, AL, 6Arthritis Power, Upper Nyack, NY, 7Global Healthy Living Foundation, CreakyJoints, Upper Nyack, NY, 8Duke University Medical Center, Durham, NC

    Background/Purpose: Women with arthritis wonder whether they will be able to have the children they desire. They also worry that oral contraceptives may worsen their…
  • Abstract Number: 1364 • 2017 ACR/ARHP Annual Meeting

    Incidence of Rheumatoid Arthritis in a Cohort of First Degree Relatives from the Studies of the Etiology of Rheumatoid Arthritis

    Diraj R. Karnani1, Lindsy J. Forbess2, Michael Weisman3, Kevin D. Deane4, V. Michael Holers5 and Jill M. Norris6, 1Department of Rheumatology, Cedars Sinai Medical Center, Los Angeles, CA, 2Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 3Cedars-Sinai Medical Center Division of Rheumatology, Los Angeles, CA, 4Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 5Rheumatology Division, University of Colorado School of Medicine, Aurora, CO, 6Department of Epidemiology, Colorado School of Public Health, Aurora, CO

    Background/Purpose: First-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) are at increased risk for developing RA compared to the general population. The purpose of…
  • Abstract Number: 1505 • 2017 ACR/ARHP Annual Meeting

    Gender Bias in the Inheritance of Ankylosing Spondylitis

    Karim Doughem1, Michael Weisman2, Lianne S. Gensler3, Mohammad H. Rahbar4, MinJae Lee4, Laura A. Diekman5, Matt Brown6, Michael Ward7 and John D. Reveille5, 1Rheumatology, The University of Texas-McGovern Medical School, Houston, TX, 2Cedars-Sinai Medical Center Division of Rheumatology, Los Angeles, CA, 3Medicine/Rheumatology, UCSF, San Francisco, CA, 4Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas-McGovern Medical School, Houston, TX, 5Rheumatology, University of Texas-McGovern Medical School, Houston, TX, 6Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, 7NIH/NIAMS, Bethesda, MD

    Background/Purpose: There are few studies of the heritability of ankylosing spondylitis (AS) in families, a disease where hereditary factors play a dominant role in disease…
  • Abstract Number: 985 • 2016 ACR/ARHP Annual Meeting

    Effectiveness of a Web-Based Personalized Rheumatoid Arthritis Risk Tool with or without a Health Educator for Knowledge of RA Risk Factors

    Maria G. Prado1, Rachel Miller Kroouze1, Zhi Yu1, Maura D. Iversen2,3,4, Nellie A. Triedman1, Sarah S. Kalia5, Kevin D. Deane6, Karen H. Costenbader1, Bing Lu1, Robert C. Green5, Elizabeth W. Karlson1 and Jeffrey A. Sparks7, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden, 3Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 6Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 7Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Much progress has been made in identifying risk factors for RA, but it is unclear whether individuals at risk for RA have knowledge of…
  • Abstract Number: 991 • 2016 ACR/ARHP Annual Meeting

    Familial Aggregation of Rheumatoid Arthritis in Sarcoidosis: A Register-Based Case-Control Study in Sweden

    Elizabeth V. Arkema, Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Sarcoidosis is an inflammatory disease with unknown etiology that primarily affects the lungs and lymph glands. Sarcoidosis shares some features with rheumatoid arthritis (RA),…
  • Abstract Number: 1022 • 2015 ACR/ARHP Annual Meeting

    Identification of Shared Genomic Regions in Distantly Related Pairs of Cases with Juvenile Idiopathic Arthritis

    Sampath Prahalad1, K. Alaine Broadaway2, John F. Bohnsack3, Ann Dodd2, Aimee O. Hersh4, Sheila T. Angeles-Han1, Se Ryeong Jang1, Marc Sudman5, Susan D. Thompson6, Michael Zwick7, Karen Conneely2 and Michael Epstein2, 1Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, 2Emory University School of Medicine, Atlanta, GA, 3Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT, 4Pediatrics/Rheumatology, University of Utah, Salt Lake City, UT, 5Divison of Rheumatology, Childrens Hospital Med Ctr, Cincinnati, OH, 6Rheumatology Dept, Childrens Hospital Med Ctr, Cincinnati, OH, 7Human Genetics, Emory University School of Medicine, Atlanta, GA

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is a complex genetic trait. While several risk variants have been identified using genome wide studies, a substantial component of…
  • Abstract Number: 1069 • 2015 ACR/ARHP Annual Meeting

    Child’s HLA-DRB1 Genotype Increases Maternal Risk of Systemic Lupus Erythematosus: Results from the Mother-Child Immunogenetic Study in Autoimmunity

    Giovanna I. Cruz1, Xiaorong Shao2, Hong L. Quach2, Janelle Noble3, Nikolaos Patsopoulos4, Michael Busch5, Darrell Triulzi6, Wendy S.W. Wong7, Benjamin Solomon7, John Niederhuber7, Lindsey A. Criswell8 and Lisa F. Barcellos2, 1School of Public Health, University of California, Berkeley, Berkeley, CA, 2Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, Berkeley, CA, 3Children's Hospital Oakland Research Institute, Oakland, CA, 4Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 5Blood Systems Research Institute, San Francisco, CA, 6Institute of Transfusion Medicine, University of Pittsburgh, Pittsburgh, PA, 7Division of Medical Genomics, Inova Translational Medicine Institute, Falls Church, VA, 8Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA

    Background/Purpose: SLE [MIM 152700] disproportionately affects women of reproductive age and pregnant patients are more likely to experience flares. Fetal microchimerism (FMC), or the persistence…
  • Abstract Number: 2101 • 2015 ACR/ARHP Annual Meeting

    HLA Associations in Mothers of Children with Cardiac Manifestations of Neonatal Lupus

    Hannah C. Ainsworth1, Carl D. Langefeld1, Miranda C. Marion2, Nathalie Costedoat-Chalumeau3, Antonio Brucato4, Jill P. Buyon5 and Robert M. Clancy5, 1Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 2Biostatistical Sciences and Center for Public Health Genomics, Wake Forest University Health Sciences, Winston-Salem, NC, 3Internal Medicine Department, Cochin Hospital, “René-Descartes Paris V” University, Paris, France, 4Internal Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy, 5Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY

    Background/Purpose: Cardiac manifestations of neonatal lupus, comprising atrioventricular conduction defects and cardiomyopathy, occur in fetuses exposed to anti-Ro/SSA antibodies, and carry substantial mortality. There is…
  • Abstract Number: 1403 • 2014 ACR/ARHP Annual Meeting

    Psychosocial Impact of Rheumatoid Arthritis Patients on Their Family Members

    Sang Wan Chung1, Ji Ae Yang2, Eun Ha Kang1, Yun Jong Lee1,3 and You Jung Ha1, 1Division of Rheumatology, Department of Internal Medicine,Seoul National University Bundang Hospital, Seongnam, South Korea, 2Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, 3Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea

    Background/Purpose Rheumatoid arthritis (RA) is a chronic inflammatory arthritis that can cause pain and functional disability, and RA patients have a higher risk of psychiatric…
  • Abstract Number: 2890 • 2014 ACR/ARHP Annual Meeting

    Does a Family History of RA Influence the Clinical Presentation and Treatment Response in RA?

    Thomas Frisell1, Saedis Saevarsdottir2,3 and Johan Askling1,4, 1Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, 2Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 3Rheumatology Unit, Dept. of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, 4Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Since family history of RA is among the strongest risk factors for developing the disease, individuals suspected to have RA are routinely asked about…
  • Abstract Number: 1767 • 2013 ACR/ARHP Annual Meeting

    Gender, Race, and Soluble Mediators Distinguish Blood Relatives Who Develop Incomplete Lupus Or Classified SLE In The Lupus Autoimmunity In Relatives (LAUREL) Study

    Melissa E. Munroe1, Kendra A. Young2, Jill M. Norris2, Joel M. Guthridge3, Diane L. Kamen4, Timothy B. Niewold5, Gary S. Gilkeson4, Michael H. Weisman6, Mariko L. Ishimori6, Daniel J. Wallace7, David R. Karp8, John B. Harley9,10 and Judith A. James11,12, 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Epidemiology, Colorado School of Public Health, Aurora, CO, 3Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, 5Division of Rheumatology and Department of Immunology, Mayo Clinic, Rochester, MN, 6Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 7Cedars-Sinai Medical Center, Los Angeles, CA, 8Rheumatic Diseases Division, UT Southwestern Medical Center, Dallas, TX, 9Division of Rheumatology and The Center for Autoimmune Genomics & Etiology, University of Cincinnati, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 10US Department of Veterans Affairs Medical Center, Cincinnati, OH, 11Oklahoma Medical Research Foundation, Oklahoma City, OK, 12College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK

    Background/Purpose: Identifying populations at risk of SLE is essential to curtail inflammatory damage and identify individuals for prevention trials. Healthy blood relatives (FDRs) of lupus…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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