Abstracts tagged "ethnic studies and systemic lupus erythematosus (SLE)"

Abstract Number: 1088 • 2018 ACR/ARHP Annual Meeting
Pro-Inflammatory and Regulatory Soluble Mediator Pathways Vary between African American and European American SLE Patients
Samantha Slight-Webb¹, Miles C. Smith¹, Holden T. Maecker², Paul J. Utz³, Joel M. Guthridge¹ and Judith A. James⁴, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Stanford University, Stanford, CA, ³Medicine, Stanford University School of Medicine, Stanford, CA, ⁴Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease that primarily affects women, and is associated with periods of elevated and suppressed clinical symptoms. SLE…
Abstract Number: 1823 • 2016 ACR/ARHP Annual Meeting
African American and European American SLE Patients with Variable Disease Activity Reveal Distinct Differences in CD4+ T Cell and Monocyte Pathways
Samantha Slight-Webb¹, Rufei Lu², Krista M. Bean¹, Holden T. Maecker³, Paul J. Utz⁴, Joel M. Guthridge⁵ and Judith A. James⁶, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁴Medicine, Stanford University School of Medicine, Stanford, CA, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disorder with both genetic and environmental contributions to disease etiology. Patients with different ancestral backgrounds have different…
Abstract Number: 643 • 2015 ACR/ARHP Annual Meeting
Ethnicity of Sjögren’s Syndrome
Rohan Sharma¹, Astrid Rasmussen², Lida Radfar³, David M. Lewis⁴, Kiely Grundahl⁵, C. Erick Kaufman⁶, Donald U. Stone⁷, Joan T. Merrill⁸, Christopher Lessard⁹, Kathy L. Sivils⁹ and Robert Hal Scofield¹⁰, ¹Medical Service, US Department of Veterans Affaris Medical Center, Oklahoma City, OK, ²Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Oral Diagnosis and Radiology Department, University of Oklahoma Health Sciences Center College of Dentistry, Oklahoma City, OK, ⁴College of Dentistry, Department of Oral and Maxillofacial Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁵Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma CIty, OK, ⁶Medicine, University of Oklahoam Health Sciences Center, Oklahoma City, OK, ⁷Ophthalmology, University of Oklahoam Health Sciences Center; Dean McGee Eye Center, Oklahoma City, OK, ⁸Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁹Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹⁰Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation; Department of Medicine, University of Oklahoma Health Sciences Center; US Department of Veterans Affairs Medical Center, Oklahoma City, OK
Background/Purpose: We undertook this study to describe the racial and ethnic diversity of SS compared to that found among patients with SLE. SLE is known…
Abstract Number: 748 • 2015 ACR/ARHP Annual Meeting
Comparison of Systemic Lupus Erythematosus in 3 Different Asian Ethnic Groups: Results from the 1000 Faces of Lupus Cohort
Mai Nguyen¹, Earl Silverman², Janet E. Pope³, Paul R. Fortin⁴, Ann E. Clarke⁵, Christian Pineau⁶, Sasha R Bernatsky⁷, C Douglas Smith⁸, Gaëlle Chédeville⁹, Lori B. Tucker¹⁰, Michel Zummer¹¹, Marie Hudson⁶, Adam M. Huber¹², Deborah M. Levy¹³, Hector Arbillaga¹⁴, Carol Hitchon¹⁵, Christine A. Peschken¹⁶ and CaNIOS 1000 Faces Investigators, ¹Medicine, University of Manitoba, Winnipeg, MB, Canada, ²Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ³University of Western Ontario, London, ON, Canada, ⁴Medicine, CHU de Québec - Université Laval, Québec, QC, Canada, ⁵Immunology/Epidemiology, Montreal General Hospital, Montreal, QC, Canada, ⁶Medicine, McGill University, Montreal, QC, Canada, ⁷Division of Rheumatolog, McGill Unversity Health Cener, Montreal, QC, Canada, ⁸The Arthritis Centre, TOH Riverside Campus, Ottawa, ON, Canada, ⁹Rheumatology, McGill University, Montreal, QC, Canada, ¹⁰Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ¹¹Rheumatology, Hôpital Maisonneuve-Rosemont and University of Montreal, Montreal, QC, Canada, ¹²Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, ¹³Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁴Calgary Rheumatology, Calgary, AB, Canada, ¹⁵University of Manitoba, Winnipeg, MB, Canada, ¹⁶Rheumatology, Univ of Manitoba, Winnipeg, MB, Canada
Background/Purpose: Ethnic variations in systemic lupus erythematosus (SLE) are well described, with more prevalent and severe disease in non-Caucasians including North American Asians. However, Asian…
Abstract Number: 689 • 2012 ACR/ARHP Annual Meeting
Activation of the Interferon Pathway Is Dependent Upon Autoantibodies in African-American SLE Patients, but Not in European-American SLE Patients
Kichul Ko¹, Yelena Koldobskaya¹, Elizabeth Rosenzweig² and Timothy B. Niewold¹, ¹Section of Rheumatology and Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL, ²Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL
Background/Purpose: Gene expression studies have been instrumental in defining important aspects of the complex immunological pathogenesis in systemic lupus erythematosus (SLE) which is a heterogeneous…

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