Abstracts tagged "epigenomics"

Abstract Number: 1789 • ACR Convergence 2021
Prediction of Psoriatic Arthritis in Patients with Psoriasis Using DNA Methylation Profiles
Omar Cruz Correa¹, Remy Pollock¹, Rohan Machhar² and Dafna Gladman³, ¹University Health Network, Toronto, ON, Canada, ²Krembil Research Institute, University Health Network, Toronto, ON, Canada, ³Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis (PsA) poses an immense clinical burden with significantly increased morbidity and mortality risk compared to psoriasis alone. PsA may develop in 30%…
Abstract Number: 783 • 2019 ACR/ARP Annual Meeting
Differences in Chromatin Architecture in Treatment Naïve Pediatric Lupus Patients
Joyce Hui-Yuen¹, Frank Jenkins ², Kaiyu Jiang ³, Susan Malkiel ², Betty Diamond ⁴ and James N. Jarvis ⁵, ¹Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY, ²Feinstein Institute for Medical Research, Manhasset, ³University at Buffalo Jacobs School of Medicine, Buffalo, NY, ⁴Feinstein Institutes for Medical Research, Manhasset, ⁵University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY
Background/Purpose: Systemic lupus erythematosus (SLE) is a complex disease likely triggered by gene-environment interactions. We have shown that most of the SLE-associated haplotypes encompass genomic…

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