Abstracts tagged "epigenetics and toll-like receptors"

Abstract Number: 871 • 2014 ACR/ARHP Annual Meeting
Antimalarials Regulate TLR7/8 Mediated Macrophage Activation Via Epigenetic Modification at the TNFα Promoter
Androo J. Markham^1,2, Mark Halushka³, Cristiana Guiducci⁴, Robert M. Clancy⁵ and Jill P. Buyon⁵, ¹Medicine, New York University School of Medicine, New York, NY, ²Medicine, Equal contributing author, New York, NY, ³Division of Cardiovascular Pathology, John Hopkins Pathology, Baltimore, MD, ⁴Discovery Department, Dynavax Technologies, Berkeley, CA, ⁵Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Maternal anti-SSA autoantibodies contribute to the pathogenesis of congenital heart block by the formation of immune complexes (IC) comprised of Ro and ssRNA (hY3)…

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Abstracts tagged "epigenetics and toll-like receptors"

Antimalarials Regulate TLR7/8 Mediated Macrophage Activation Via Epigenetic Modification at the TNFα Promoter