Epigenetics and systemic sclerosis Archives

Abstract Number: 754 • ACR/ARHP Annual Meeting 2014
The Global miRNA Whole Blood Profile in Systemic Sclerosis and Its Correlation with Serum Cytokine Levels
Gloria Salazar¹, Maureen Mayes², John Hagan³, Minghua Wu¹, John D. Reveille^4,5 and Shervin Assassi¹, ¹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ²Internal Medicine/Rheumatology, University of TX Health Science Center -Houston, Houston, TX, ³Neurosurgery, University of Texas at Houston, Houston, TX, ⁴Internal Medicine/Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ⁵Internal Medicine/Rheumatology, Univ of Texas Health Science Center at Houston, Houston, TX
The Global miRNA Whole Blood Profile in Systemic Sclerosis and its Correlation with Serum Cytokine LevelsBackground/Purpose: Several studies have implicated miRNAs in the pathogenesis of…
Abstract Number: 1902 • ACR/ARHP Annual Meeting 2013
Characterization Of HLA-DRB1 Distribution By 3rd Hypervariable Region Sequence In Systemic Sclerosis and Control Populations
Coline, A. Gentil¹, Hilary S. Gammill¹, Christine, T. Luu¹ and J. Lee Nelson², ¹Immunogenetics, Fred Hutchinson Cancer Research Center, SEATTLE, WA, ²Immunogenetics D2-100, Fred Hutchinson Cancer Rsch, Seattle, WA
Background/Purpose: HLA class II genes are associated with a wide spectrum of autoimmune diseases. Specific alleles at the DRB1, DQA1 and DQB1 loci are associated…
Abstract Number: 655 • ACR/ARHP Annual Meeting 2013
DNA Methylation and Systemic Sclerosis
Gloria Salazar¹, Khurshida Begum², Xinjian Guo³, Minghua Wu¹, Shervin Assassi¹, Maureen D. Mayes¹, John D. Reveille¹ and Xiaodong Zhou¹, ¹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ²Baylor College of Medicine, Houston, TX, ³Rheumatology, The University of Texas Medical School at Houston, Houston, TX
DNA Methylation and Systemic SclerosisBackground/Purpose: Epigenetic modiﬁcations are stable and heritable alterations in gene expression and cellular function that do not involve changes to the…
Abstract Number: 783 • ACR/ARHP Annual Meeting 2012
The Wnt Inhibitors DKK1 and SFRP1 Are Downregulated by Promoter Hypermethylation in Systemic Sclerosis
Clara Dees¹, Inga Schlottmann¹, Robin Funke¹, Alfiya Distler², Katrin Palumbo-Zerr², Pawel Zerr², Oliver Distler³, Georg A. Schett⁴ and Joerg HW Distler², ¹Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ³Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Tissue fibrosis caused by pathological activation of fibroblasts is a major hallmark of systemic sclerosis (SSc). Epigenetic gene silencing of anti-fibrotic genes such as…

Abstracts tagged "Epigenetics and systemic sclerosis"

The Global miRNA Whole Blood Profile in Systemic Sclerosis and Its Correlation with Serum Cytokine Levels

Characterization Of HLA-DRB1 Distribution By 3rd Hypervariable Region Sequence In Systemic Sclerosis and Control Populations

DNA Methylation and Systemic Sclerosis

The Wnt Inhibitors DKK1 and SFRP1 Are Downregulated by Promoter Hypermethylation in Systemic Sclerosis