Abstracts tagged "Epigenetics and systemic sclerosis"

Abstract Number: 754 • 2014 ACR/ARHP Annual Meeting
The Global miRNA Whole Blood Profile in Systemic Sclerosis and Its Correlation with Serum Cytokine Levels
Gloria Salazar¹, Maureen Mayes², John Hagan³, Minghua Wu¹, John D. Reveille^4,5 and Shervin Assassi¹, ¹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ²Internal Medicine/Rheumatology, University of TX Health Science Center -Houston, Houston, TX, ³Neurosurgery, University of Texas at Houston, Houston, TX, ⁴Internal Medicine/Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ⁵Internal Medicine/Rheumatology, Univ of Texas Health Science Center at Houston, Houston, TX
The Global miRNA Whole Blood Profile in Systemic Sclerosis and its Correlation with Serum Cytokine LevelsBackground/Purpose: Several studies have implicated miRNAs in the pathogenesis of…
Abstract Number: 1902 • 2013 ACR/ARHP Annual Meeting
Characterization Of HLA-DRB1 Distribution By 3rd Hypervariable Region Sequence In Systemic Sclerosis and Control Populations
Coline, A. Gentil¹, Hilary S. Gammill¹, Christine, T. Luu¹ and J. Lee Nelson², ¹Immunogenetics, Fred Hutchinson Cancer Research Center, SEATTLE, WA, ²Immunogenetics D2-100, Fred Hutchinson Cancer Rsch, Seattle, WA
Background/Purpose: HLA class II genes are associated with a wide spectrum of autoimmune diseases. Specific alleles at the DRB1, DQA1 and DQB1 loci are associated…
Abstract Number: 655 • 2013 ACR/ARHP Annual Meeting
DNA Methylation and Systemic Sclerosis
Gloria Salazar¹, Khurshida Begum², Xinjian Guo³, Minghua Wu¹, Shervin Assassi¹, Maureen D. Mayes¹, John D. Reveille¹ and Xiaodong Zhou¹, ¹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ²Baylor College of Medicine, Houston, TX, ³Rheumatology, The University of Texas Medical School at Houston, Houston, TX
DNA Methylation and Systemic SclerosisBackground/Purpose: Epigenetic modiﬁcations are stable and heritable alterations in gene expression and cellular function that do not involve changes to the…
Abstract Number: 783 • 2012 ACR/ARHP Annual Meeting
The Wnt Inhibitors DKK1 and SFRP1 Are Downregulated by Promoter Hypermethylation in Systemic Sclerosis
Clara Dees¹, Inga Schlottmann¹, Robin Funke¹, Alfiya Distler², Katrin Palumbo-Zerr², Pawel Zerr², Oliver Distler³, Georg A. Schett⁴ and Joerg HW Distler², ¹Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ³Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Tissue fibrosis caused by pathological activation of fibroblasts is a major hallmark of systemic sclerosis (SSc). Epigenetic gene silencing of anti-fibrotic genes such as…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].