Abstracts tagged "epigenetics and rheumatic disease"

Abstract Number: 73 • 2016 ACR/ARHP Annual Meeting
Dysregulation of Hypomethylated Age-Related CpG Sites Characterize T-Cells and Monocytes from Treatment Naive Rheumatoid Arthritis Subjects
Ines Colmegna¹, Marie Forest², Aurelie Labbe³, Sasha Bernatsky⁴, Jose Navarro⁵, Tomi Pastinen⁶, Celia Greenwood⁷ and Marie Hudson⁸, ¹Medicine, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ²Jewish General Hospital, Lady Davis Research Institute, Montreal, QC, Canada, ³Epidemiology, Biostatistics & Occupational Health, McGill University, Montreal, QC, Canada, ⁴Division of Rheumatology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁵Experimental Medicine, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁶Human Genetics, McGill University, Montreal, QC, Canada, ⁷Centre for Clinical Epidemiology, Jewish General Hospital, Lady Davis Research Institute, Montreal, QC, Canada, ⁸Medicine/Rheumatology, Jewish General Hospital, Lady Davis Research Institute, Montreal, QC, Canada
Background/Purpose: In the general population, an increase in chronological age is associated with differential DNA methylation of particular CpGs in a highly conserved fashion. Since…

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