Abstracts tagged "epigenetics and biomarkers"

Abstract Number: 32 • 2019 ACR/ARP Annual Meeting
Aberration of Histone Lysine Methylation in Adult-Onset Still’s Disease Are Novel Biomarker Candidates Associated with the Disease Activity
Yoshimi Aizaki¹, Yasuto Araki ¹, Kojiro Sato ² and Toshihide Mimura ¹, ¹Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, ²Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Tochigi, Japan
Background/Purpose: Adult-onset Still’s disease (AOSD) is a systemic autoinflammatory disorder characterized by spiking fever, transient rash, arthritis and leukocytosis. Macrophage and neutrophil activation is a…