Abstracts tagged "Epidemiologic methods"

Abstract Number: 393 • 2015 ACR/ARHP Annual Meeting
From Childhood to Adulthood: Identifying Latent Classes of Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus Patients
Lily Siok Hoon Lim¹, Eleanor Pullenayegum², Lillian Lim³, Dafna Gladman⁴, Brian Feldman⁵ and Earl Silverman⁶, ¹Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ²Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada, ³Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ⁶Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada
Background/Purpose: Although SLE patients are thought to follow different patterns of disease courses, no information is available about the longitudinal disease activity or the number…
Abstract Number: 2023 • 2015 ACR/ARHP Annual Meeting
Breastfeeding, Oral Contraceptive and the Risk of Rheumatoid Arthritis: Results from the Swedish Epidemiological Investigation of RA Study
Cecilia Orellana¹, Lars Klareskog², Lars Alfredsson^3,4 and Camilla Bengtsson¹, ¹Karolinska Institutet, Institute of Environmental Medicine, Stockholm, Sweden, ²Department of Medicine, Karolinska University Hospital, Stockholm, Sweden, ³Karolinska Institute, Institute of Environmental Medicine, Stockholm, Sweden, ⁴Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Breastfeeding (BF) has been associated with both a decreased and an increased risk of developing rheumatoid arthritis (RA). Regarding oral contraceptive (OC) use and…
Abstract Number: 437 • 2015 ACR/ARHP Annual Meeting
Is Mode of Action Important When Switching Biologic Monotherapy in Rheumatoid Arthritis? Drug Adherence Results from the Swedish Ssatg Registry
Tanja Schjødt Jørgensen¹, Carl Turesson², Meliha C. Kapetanovic³, Martin Englund^4,5, Aleksandra Turkiewicz⁴, Robin Christensen¹, Henning Bliddal¹, Pierre Geborek³ and Lars Erik Kristensen¹, ¹The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ²Lund University, Rheumatology, Dept. of Clinical Sciences,, Malmö, Sweden, ³Department of Clinical Sciences Lund, Section of Rheumatology Lund University and Skåne University Hospital, Lund, Sweden, ⁴Orthopedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, ⁵Clinical Epidemiology Unit, Orthopedics, Dept of Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: About 30% of patients receiving biologic therapy do not have concomitant conventional synthetic DMARDs (csDMARDs). Little is known about the role of different mode…
Abstract Number: 2167 • 2015 ACR/ARHP Annual Meeting
Application of Combined Reporting of Benefit and Harm (OMERACT 3×3 methodology) to the Rheumatoid Arthritis Comparison of Active Therapies Trial
Maarten Boers^1,2, Sarah Leatherman³, James R. O'Dell⁴ and Jeffrey R. Curtis⁵, ¹Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands, ²Amsterdam Rheumatology and immunology Center, VU University Medical Center, Amsterdam, Netherlands, ³MAVERIC CSPCC (151MAV), VA Boston Healthcare System, Boston, MA, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵Birmingham VAMC, Birmingham, AL
Background/Purpose: The Outcome Measures in Rheumatology (OMERACT) Initiative has suggested an analysis of the occurrence of benefit and harm in trials simultaneously, at the individual…
Abstract Number: 911 • 2015 ACR/ARHP Annual Meeting
Patients with Rheumatoid Arthritis Are at Increased Risk of Both Ischemic and Non-Ischemic Heart Failure
Ängla Mantel¹, Marie Holmqvist¹, Daniel Andersson^2,3, Lars Lund^2,3 and Johan Askling^4,5, ¹Dept of Medicine, Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, ²Department of medicine, Karolinska Institutet, Cardiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, ³Karolinska university hospital, Cardiology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁴Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁵Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Studies among unselected patients with rheumatoid arthritis (RA) suggest increased risks of both ischemic and non-ischemic heart failure (HF). Since the risk of these…
Abstract Number: 2168 • 2015 ACR/ARHP Annual Meeting
The Smoking Paradox in the Development of Myocardial Infarction Among Rheumatoid Arthritis Patients
Uyen Sa D.T. Nguyen¹, Yuqing Zhang², Na Lu³, Jingbo Niu⁴, David T. Felson⁴, Michael P. Lavalley⁵, Jeffrey A. Sparks⁶, Shun-Chiao Chang⁷, Elizabeth W. Karlson⁸ and Hyon K. Choi³, ¹Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ²Clinical Epidemilogy and Training Unit, Boston University School of Medicine, Boston, MA, ³Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Biostatistics, Boston University, Boston, MA, ⁶Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, ⁷Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁸Rheumatology, Brigham & Women's Hospital, Boston, MA
Background/Purpose: Smoking is a strong risk factor for myocardial infarction (MI), but not among rheumatoid arthritis (RA) patients. These paradoxical findings may be due to…
Abstract Number: 46 • 2015 ACR/ARHP Annual Meeting
Feasibility Study of Smartphone Data Collection for Cloudy with a Chance of Pain: Sustained Engagement for Daily Self-Reporting of Disease Severity in Rheumatoid Arthritis over Two Months
Samuel Reade¹, Jamie C Sergeant^2,3, Matthew Sperrin⁴, David M. Schultz⁵, Karen Spencer⁶, Caroline Sanders⁶ and William G Dixon⁷, ¹The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, ⁴Institute of Population Health, Health e-Research Centre, The University of Manchester, Manchester, United Kingdom, ⁵Faculty of Engineering and Physical Sciences, School of Earth, Atmospheric and Environmental Sciences, The University of Manchester, Manchester, United Kingdom, ⁶Institute of Population Health, Centre for Primary Care, The University of Manchester, Manchester, United Kingdom, ⁷Manchester Academic Health Sciences Centre, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Previous research has attempted to study the association between weather and joint pain. Inconclusive results may be due, in part, to infrequent measures of…
Abstract Number: 912 • 2015 ACR/ARHP Annual Meeting
Secondary Preventive Pharmacotherapy and Longterm Outcomes Following Acute Coronary Events in Patients with Prevalent Rheumatoid Arthritis
Ängla Mantel¹, Marie Holmqvist¹, Tomas Jernberg², Solveig Wållberg-Jonsson³ and Johan Askling^4,5, ¹Dept of Medicine, Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, ²Section of Cardiology, Department of medicine, Karolinska University Hospital, Stockholm, Sweden, ³Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, ⁴Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁵Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Suboptimal use of secondary preventive pharmacotherapies after acute coronary syndrome (ACS) in patients with rheumatoid arthritis (RA) has been suggested to contribute to an…
Abstract Number: 2244 • 2015 ACR/ARHP Annual Meeting
Risk of Incident Atrial Fibrillation in Gout
Seoyoung C. Kim¹, Jun Liu² and Daniel H. Solomon³, ¹Div. of Pharmacoepidemiology and Pharmacoeconomics, Div. of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Division of Pharmacoepidemiology, Brigham and Women's Hospital, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Atrial fibrillation (AF) is the most common arrhythmia associated with cardiovascular disease and mortality. There are increasing data supporting the role of inflammation in…
Abstract Number: 915 • 2015 ACR/ARHP Annual Meeting
Defining Pain for Fibromyalgia Criteria: Multi-Site or Widespread? an Analysis of Data from Four UK Population-Based Studies
Gary J. Macfarlane¹, Linda E. Dean¹, Robert Bennett², Leslie J. Crofford³, Abimbola Ayorinde¹, Elisa Fluess¹, Daniel J. Clauw⁴, Mary-Ann Fitzcharles⁵, Don Goldenberg⁶, Eduardo Paiva⁷, Roland Staud⁸ and Lesley Arnold⁹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²SN-Office of Research & Development, Oregon Health & Science Univ, Portland, OR, ³Medicine, Vanderbilt University, Nashville, TN, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI, ⁵MGH, Montreal, QC, Canada, ⁶Newton-Wellesley Hospital, Newton, MA, ⁷Sociedade Brasileira de Reumatologia, São Paulo, Brazil, ⁸University of Florida, Gainesville, FL, ⁹University of Cincinnati, Cincinnati, OH
Background/Purpose: The 1990 criteria for fibromyalgia (FM) remain the only set approved by the American College of Rheumatology (ACR). They require that pain be both…
Abstract Number: 2254 • 2015 ACR/ARHP Annual Meeting
Socio-Economically Deprived Patients Have a Higher Likelihood for Having Any Type of Rheumatic and Musculoskeletal Diseases and Have Higher Healthcare Costs – Results from a Population-Based Administrative Database Including 1.9 Million Persons (Basque country, Spain)
Polina Putrik¹, Sofia Ramiro², Jon Orueta³, Edurne Alonso Moran⁴, Roberto Nuno Solinis⁵ and Annelies Boonen⁶, ¹Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Centro de Salud de Astrabudua, Osakidetza, Basque Health Service, Erandio, Spain, ⁴O+berri, Basque Institute for Healthcare Innovation, Barakaldo, Spain, ⁵Universidad Deusto, Bilbao, Spain, ⁶Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: Rheumatic and musculoskeletal diseases (RMDs) are prevalent and have a strong impact on health care costs. Some evidence in specific diseases indicates that patients…
Abstract Number: 1069 • 2015 ACR/ARHP Annual Meeting
Child’s HLA-DRB1 Genotype Increases Maternal Risk of Systemic Lupus Erythematosus: Results from the Mother-Child Immunogenetic Study in Autoimmunity
Giovanna I. Cruz¹, Xiaorong Shao², Hong L. Quach², Janelle Noble³, Nikolaos Patsopoulos⁴, Michael Busch⁵, Darrell Triulzi⁶, Wendy S.W. Wong⁷, Benjamin Solomon⁷, John Niederhuber⁷, Lindsey A. Criswell⁸ and Lisa F. Barcellos², ¹School of Public Health, University of California, Berkeley, Berkeley, CA, ²Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, Berkeley, CA, ³Children's Hospital Oakland Research Institute, Oakland, CA, ⁴Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ⁵Blood Systems Research Institute, San Francisco, CA, ⁶Institute of Transfusion Medicine, University of Pittsburgh, Pittsburgh, PA, ⁷Division of Medical Genomics, Inova Translational Medicine Institute, Falls Church, VA, ⁸Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA
Background/Purpose: SLE [MIM 152700] disproportionately affects women of reproductive age and pregnant patients are more likely to experience flares. Fetal microchimerism (FMC), or the persistence…
Abstract Number: 2284 • 2015 ACR/ARHP Annual Meeting
Age and Sex Stratified Normative Data for Shoulder Range of Movement
Tiffany K. Gill¹, E. Michael Shanahan^2,3, Graeme R Tucker¹ and Catherine Hill^4,5, ¹Medicine, The University of Adelaide, Adelaide, Australia, ²Rheumatology, Flinders University, Bedford Park, South Australia, Australia, ³Repat General Hospital, Flinders University, Adelaide, Australia, ⁴Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia, ⁵The Health Observatory, The University of Adelaide, Adelaide, Australia
Background/Purpose: Shoulder range of movement is integral to activities of daily living and the impact of pain on shoulder function has a significant effect on…
Abstract Number: 1083 • 2015 ACR/ARHP Annual Meeting
Nationwide Trends in Hospitalization and in-Hospital Mortality Associated with Granulomatosis with Polyangiitis (GPA)
Zachary Wallace¹, John H. Stone², Hyon K. Choi³, Na Lu³, Sebastian Unizony³ and Eli Miloslavsky⁴, ¹Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ³Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Division of Rheumatology, Massachusetts General Hopsital, Boston, MA
Background/Purpose: Granulomatosis with polyangiitis (GPA) is associated with severe end-organ damage (e.g., renal failure) and treatment-related complications (e.g., severe infection) which often lead to hospitalization…
Abstract Number: 2412 • 2015 ACR/ARHP Annual Meeting
Assessment and Comparison of Responsiveness of Four Patient Reported Outcome Measures to Assess Physical Function in Patients with Knee Osteoarthritis: WOMAC-PF Subscale Responds Best
Elien A.M. Mahler¹, Nienke Cuperus², Johannes W J Bijlsma³, Thea Vliet Vlieland⁴, Frank H.J. van den Hoogen⁵, Alfons den Broeder⁵ and Cornelia H.M. van den Ende¹, ¹Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Rheumatology Department, Sint Maartenskliniek, Nijmegen, Netherlands, ³Rheumatology and Clinical Immunology, ARC Amsterdam; UMC Utrecht, Utrecht, Netherlands, ⁴Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Although physical function is one of the core outcome domains in knee osteoarthritis (OA), the ability of a measurement instrument to detect changes over…

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