Abstracts tagged "Epidemiologic methods"

Abstract Number: 1207 • 2015 ACR/ARHP Annual Meeting
Predictive Utility of Anti- Citrullinated Peptide Antibodies and Rheumatoid Factor – a Retrospective Dataanalysis
Miriam Gärtner, Mathias Schneeweiss, Josef S. Smolen and Klaus Machold, Department of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Antibody profiling encompassing rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA) supports diagnosis in patients with Rheumatoid arthritis (RA). However, RF and ACPA are…
Abstract Number: 2943 • 2015 ACR/ARHP Annual Meeting
Preliminary Population-Based Incidence and Prevalence Estimates of Systemic Lupus Erythematous from the Manhattan Lupus Surveillance Program
Peter M. Izmirly¹, Isabella Wan², Sara Sahl¹, Jill P. Buyon³, H. Michael Belmont⁴, Jane E. Salmon^5,6, Joan M. Bathon⁷, Anca Askanase⁸, Laura Geraldino-Pardilla⁹, Yousaf Ali¹⁰, Ellen M. Ginzler¹¹, Chaim Putterman¹², Caroline Gordon¹³, Charles G. Helmick¹⁴ and Hilary Parton¹⁵, ¹Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Rheumatology, New York University School of Medicine, New York, NY, ³Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁴New York University School of Medicine, New York, NY, ⁵Dept of Medicine, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, ⁶Rheumatology, Hospital for Special Surgery, New York, NY, ⁷Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁸Columbia University College of Physicians & Surgeons, New York, NY, ⁹Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ¹⁰Icahn School of Medicine at Mount Sinai, New York, NY, ¹¹Medicine/Box 42, SUNY-Downstate, Brooklyn, NY, ¹²Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ¹³School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, ¹⁴Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ¹⁵Bureau of Epidemiology Services, New York City Department of Health and Mental Hygiene, Long Island City, NY
Background/Purpose: Given widely varying estimates of the incidence and prevalence of Systemic Lupus Erythematous (SLE) in the US and the absence of data for certain…
Abstract Number: 1209 • 2015 ACR/ARHP Annual Meeting
Associations Between Rheumatoid Arthritis (RA)-Related Autoimmunity, Joint Symptoms, and Physical Activity in First-Degree Relatives without RA in a Prospective Cohort
Jan M. Hughes-Austin¹, Joachim H. Ix², Samuel R. Ward³, Michael H. Weisman⁴, James R. O'Dell⁵, Ted R. Mikuls⁵, Jane H. Buckner⁶, Peter K. Gregersen⁷, Richard M. Keating⁸, Kevin D. Deane⁹, V. Michael Holers¹⁰ and Jill M. Norris¹¹, ¹Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, ²University of California, San Diego, La Jolla, CA, ³Radiology, Orthopaedic Surgery, and Bioengineering, University of California, San Diego, La Jolla, CA, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶Benaroya Research Institute at Virginia Mason, Seattle, WA, ⁷Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Med Res, Manhasset, NY, ⁸Division of Rheumatology, Scripps Health, La Jolla, CA, ⁹Division of Rheumatology, U Colo Denver, Aurora, CO, ¹⁰Rheumatology Division, Univ of Colorado School of Med, Aurora, CO, ¹¹University of Colorado Denver, Aurora, CO
Background/Purpose: Physical activity in RA patients is significantly less than in counterparts without RA, and many live just above the muscle strength threshold needed for…
Abstract Number: 3163 • 2015 ACR/ARHP Annual Meeting
The Smoking Paradox in the Development of Psoriatic Arthritis Among Psoriasis Patients
Uyen Sa D.T. Nguyen¹, Yuqing Zhang², Na Lu³, Qiong Louie-Gao⁴, Jingbo Niu⁵, David T. Felson⁵, Michael P. Lavalley⁶, Thorvardur Love^7,8, Maureen Dubreuil⁴, Jeffrey A. Sparks⁹, Elizabeth W. Karlson¹⁰ and Hyon K. Choi³, ¹Orthopedics & Physical Rehabilation, Univerity of Massachusetts Medical School, Worcester, MA, ²Clinical Epidemilogy and Training Unit, Boston University School of Medicine, Boston, MA, ³Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Boston University School of Medicine, Boston, MA, ⁵Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁶Biostatistics, Boston University, Boston, MA, ⁷Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁸Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ⁹Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, ¹⁰Rheumatology, Brigham & Women's Hospital, Boston, MA
Background/Purpose: Smoking is a strong risk factor of psoriasis, but a previous study has suggested that smoking protects against the development of psoriatic arthritis (PsA)…
Abstract Number: 211 • 2015 ACR/ARHP Annual Meeting
The Epidemiology of Gout: Marked Increase in Incidence and Comorbidities over 20 Years
Mohanad Elfishawi¹, Nour Zleik¹, Zoran Kvrgic¹, Clement J. Michet Jr.², Cynthia S. Crowson³, Eric L. Matteson⁴ and Tim Bongartz¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: Several studies have suggested that the prevalence of gout has increased over recent years. The majority of this data has been derived from insurance…
Abstract Number: 1450 • 2015 ACR/ARHP Annual Meeting
Clostridium Difficile Infection-Associated Reactive Arthritis in a Pediatric Cohort
Daniel B. Horton^1,2,3, Brian L. Strom^1,3, Mary E. Putt³, Carlos D. Rose², David D. Sherry⁴ and Julia S. Sammons⁵, ¹Rutgers Biomedical and Health Sciences, New Brunswick, NJ, ²Pediatrics, Nemours A.I. duPont Hospital for Children, Division of Pediatric Rheumatology, Thomas Jefferson University, Wilmington, DE, ³Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics, Children's Hospital of Philadelphia, Division of Pediatric Rheumatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁵Pediatrics, Infection Prevention and Control, Division of Infectious Diseases, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: The incidence of Clostridium difficile infection (CDI) has increased among children, and CDI is associated with significant morbidity and mortality. Cases of C. difficile…
Abstract Number: 234 • 2015 ACR/ARHP Annual Meeting
Weight Variables and Their Association with Serum Urate Concentrations and Hyperuricemia in Young Adults
Angelo L. Gaffo^1,2, David R. Jacobs Jr.³, Huifen Wang⁴ and Kenneth G. Saag⁵, ¹Rheumatology, Birmingham VA Medical Center, Birmingham, AL, ²Medicine, University of Alabama at Birmingham, Birmingham, AL, ³Epidemiology, University of Minnesota, Minneapolis, MN, ⁴Nutritional Epidemiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: How body weight, anthropometric parameters, and their changes are associated with serum urate concentrations and hyperuricemia remains unclear. The CARDIA study has been following…
Abstract Number: 1453 • 2015 ACR/ARHP Annual Meeting
Surveillance of Periodic Fever Syndromes in Canada
Paul Dancey^1,2, Susanne Benseler³, Marco Gattorno⁴, Anne K Junker⁵, Ronald Laxer⁶, Paivi Miettunen⁷ and Lesley Ann Turner⁸, ¹Health Science Centre, Memorial University of Newfoundland, St Johns, NF, Canada, ²Pediatrics, Janeway Children's Hospital, St. John's, NF, Canada, ³Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, ⁴Pediatry, G. Gaslini Institute, Genova, Italy, ⁵University of British Columbia, Vancouver, BC, Canada, ⁶The Hospital for Sick Children, Toronto, ON, Canada, ⁷University of Calgary, Calgary, AB, Canada, ⁸Memorial University, St. John's, NF, Canada
Background/Purpose: To estimate the incidence of periodic fever syndromes in the Canadian paediatric population, to describe the patterns of presentation, and to raise awareness in…
Abstract Number: 242 • 2015 ACR/ARHP Annual Meeting
Higher Serum Uric Acid Levels Are Associated with an Increased Risk of Flares: A Systematic Review
Aki Shiozawa¹, Shelagh M Szabo², Antoinette Cheung², Anna Bolzani² and Hyon K. Choi³, ¹Global Outcomes and Epidemiology Research, Takeda Pharmaceuticals International, Inc, Deerfield, IL, ²Redwood Outcomes, Vancouver, BC, Canada, ³Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Acutely painful flares represent the typical clinical burden of gout. Effective therapy can reduce serum uric acid (sUA) levels; however, epidemiologic evidence for the…
Abstract Number: 1546 • 2015 ACR/ARHP Annual Meeting
What Is the Impact of Smoking on the Risk of Rheumatoid Arthritis Progression: A Systematic Review of the Risk Factor Paradox
Sharan K. Rai¹, Natalie McCormick², Uyen Sa D.T. Nguyen³, Yuqing Zhang⁴, Jeffrey A. Sparks⁵, Elizabeth W. Karlson⁶ and Hyon K. Choi⁷, ¹Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, ²Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Clinical Epidemilogy and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, ⁶Rheumatology, Brigham & Women's Hospital, Boston, MA, ⁷Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to progressive joint deformity, destruction, and disability. While smoking is recognized as a strong…
Abstract Number: 338 • 2015 ACR/ARHP Annual Meeting
Smoking and Alcohol Use Are Associated with Structural and Inflammatory Hand Osteoarthritis Features in a Population Based Study
Karin Magnusson¹, Alexander Mathiessen², Hilde Berner Hammer², Bård Natvig³, Kåre Birger Hagen¹, Nina Østerås¹ and Ida K. Haugen⁴, ¹Department of Rheumatology, National Advisory Unit on Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³General Practice, Oslo University, Oslo, Norway, ⁴Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Smoking has been shown to have a potential protective effect on radiographic knee osteoarthritis (OA), possibly mediated through lower body weight in smokers. A…
Abstract Number: 1706 • 2015 ACR/ARHP Annual Meeting
Prevalence and Factors Associated with Non-Traumatic Vertebral Fractures in Psoriatic Arthritis
Shelly Chandran¹, Sindhu R. Johnson², Angela Cheung³, David Salonen⁴ and Dafna Gladman⁵, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Dept of Rheumatology, Toronto Western and Mt. Sinai Hospitals, University of Toronto, Toronto, ON, Canada, ³Department of Medicine, University of Toronto, Toronto, ON, Canada, ⁴Department of Medical Imaging, University Health Network, Toronto, ON, Canada, ⁵Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: The prevalence of osteoporotic vertebral fractures (VF) in psoriatic arthritis (PsA) is not known. We aim to determine the prevalence and factors associated with…
Abstract Number: 373 • 2015 ACR/ARHP Annual Meeting
Compared to Non-Users, Current Glucocorticoids Users Have Less Prevalent Fractures at the Same Bone Mass: Results of a Large Cross-Sectional Study
Marwan Bukhari¹, Nicola Goodson^2,3 and Maarten Boers⁴, ¹Rheumatology, Royal Lancaster Infirmary, Consultant and Honorary Senior Lecturer, Lancaster, United Kingdom, ²Rheumatology, University of Liverpool, Liverpool, United Kingdom, ³Rheumatology, University Hospital Aintree, Liverpool, United Kingdom, ⁴Amsterdam Rheumatology and Immunology Center, VU University Medical center, Amsterdam, Netherlands
Background/Purpose: It is widely believed that use of glucocorticoids (GC) increase risk of fracture through reduction in bone quality as well as reduction in bone…
Abstract Number: 1972 • 2015 ACR/ARHP Annual Meeting
Cardiovascular and Cerebrovascular Disease and Social Deprivation in Patients with Giant Cell Arteritis
Joanna Robson¹, Amit Kiran², Andrew Hutchings³, Joseph Maskell⁴, Nigel K Arden⁵, Willie Hamilton⁶, Bhaskar Dasgupta^7,8 and Raashid Luqmani⁹, ¹Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, University of Oxford, Oxford, United Kingdom, ²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom, ³Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁴Faculty of Medicine, University of Southampton, Southampton, United Kingdom, ⁵Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, ⁶Primary Care, University of Exeter, Exeter, United Kingdom, ⁷Southend University Hospital, Southend, United Kingdom, ⁸Rheumatology, Southend University Hospital, Essex, United Kingdom, ⁹Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis in the UK, with an incidence of 2.2 cases per 10,000 person-years. Cerebrovascular…
Abstract Number: 392 • 2015 ACR/ARHP Annual Meeting
From Childhood to Adulthood: Longitudinal Trajectory of Damage in Patients with Childhood-Onset Systemic Lupus Erythematosus (cSLE)
Lily Siok Hoon Lim^1,2,3,4, Eleanor Pullenayegum⁵, Lillian Lim⁶, Dafna Gladman⁷, Brian Feldman⁸ and Earl Silverman⁹, ¹Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada, ²Rheumatology, SickKids, Toronto, ON, Canada, ³Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ⁴Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada, ⁵Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, ⁶Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁷Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ⁹Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada
Background/Purpose: Outcomes of patients with cSLE over time and into adulthood are poorly understood. There has been no information about the longitudinal trajectory of organ…

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