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Abstracts tagged "Epidemiologic methods and systemic lupus erythematosus (SLE)"

  • Abstract Number: 2804 • 2018 ACR/ARHP Annual Meeting

    Identifying Lupus Patients in Electronic Health Records: Development and Validation of Machine Learning Algorithms and Application of Rule-Based Algorithms

    April Jorge1, Victor M. Castro2, April Barnado3, Vivian Gainer2, Chuan Hong4, Tianxi Cai2, Robert Carroll5, Leslie Crofford3, Karen Costenbader6, Katherine P. Liao7, Elizabeth Karlson6 and Candace H. Feldman6, 1Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Research Information Systems and Computing, Partners Healthcare, Boston, MA, 3Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN, 4Harvard T.H. Chan School of Public Health, Boston, MA, 5Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 6Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 7Brigham and Women's Hospital, Boston, MA

    Background/Purpose: To utilize electronic health records (EHR) to study SLE, phenotypic algorithms are needed to accurately identify these patients. We aimed to generate an EHR…
  • Abstract Number: 149 • 2015 ACR/ARHP Annual Meeting

    Characteristics of Patients Diagnosed with Systemic Lupus Erythematosus (SLE) Initiating Treatment with Belimumab in a US Commercially Insured Database: 2010-2014

    Deanna Hill1, Hong Kan2, Peter Egger3, David J. Chang4, Amanda Eudy1,5, Joe Maskell3 and Karen H. Costenbader6, 1Worldwide Epidemiology, GlaxoSmithKline, Collegeville, PA, 2Value Evidence and Outcomes, GlaxoSmithKline, Research Triangle Park, NC, 3Worldwide Epidemiology, GlaxoSmithKline, Stockley Park, United Kingdom, 4US Medical Affairs, GlaxoSmithKline, Philadelphia, PA, 5Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 6Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Belimumab, a B-lymphocyte stimulator, was FDA-approved March 2011 for the treatment of adult patients with active, autoantibody-positive SLE receiving standard of care (SOC) medications.…
  • Abstract Number: 990 • 2015 ACR/ARHP Annual Meeting

    Performance of the Systemic Lupus International Collaborating Clinic Classification Criteria Versus the 1982 and Revised 1997 American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus: A Population-Based Study

    Patompong Ungprasert1, Cynthia S. Crowson2 and Vaidehi Chowdhary1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease with heterogeneous presentations. Therefore, classification criteria are required to help improve diagnostic accuracy in clinical practice…
  • Abstract Number: 3158 • 2015 ACR/ARHP Annual Meeting

    Impact of Family History of Systemic Lupus Erythematosus on Risk of Autoimmune Diseases: National Cohort Study in Denmark 1977-2012

    Constance Jensina Ulff-Møller1, Jacob Simonsen2, Søren Jacobsen1 and Morten Frisch2, 1Department of Rheumatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, 2Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark

    Background/Purpose: Systemic lupus erythematosus (SLE) is a complex autoimmune disease (AID), which develops through the interplay of genetic, epigenetic and environmental factors and may cluster…
  • Abstract Number: 2510 • 2013 ACR/ARHP Annual Meeting

    The Epidemiology Of Systemic LUPUS Erythematosus and Clinical Features Of Patients At A Single Center In Northwestern Turkey

    Omer Nuri Pamuk1, Salim Dönmez2, Gokce Busra Calayir3 and Cigdem Mengus4, 1Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, 2Rheumatology, Yüzüncü Yıl University Medical Faculty, Edirne, Turkey, 3Rheumatology, Trakya University Medical Faculty, Edirne, Turkey, 4Internal Medicine, Trakya University Medical Faculty, Edirne, Turkey

    Background/Purpose: We evaluated  the clinical features, treatment modalities, treatment responses and prognosis of patients diagnosed with systemic lupus erythematosus (SLE). We also estimated the prevalence…
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