Abstracts tagged "environmental factors and rheumatoid arthritis (RA)"

Abstract Number: 214 • 2018 ACR/ARHP Annual Meeting
Exploring the Relation between Air Pollution and Disease Activity in Patients with Rheumatoid Arthritis
Tommaso Schioppo¹, Valentina Bollati^2,3, Chiara Favero^2,3, Nicola Ughi¹, Isabella Scotti¹, Valeria Merlino¹, Orazio De Lucia¹, Antonella Murgo¹ and Francesca Ingegnoli^1,3, ¹Division of Clinical Rheumatology, G. Pini Hospital, Milan, Italy, ²EPIGET Lab, Milan, Italy, ³Dept. of Clinical Sciences & Community Health, Università degli Studi di Milano, Milan, Italy
Background/Purpose: Disease remission is considered an achievable target in a significant proportion of patients with rheumatoid arthritis (RA). Nevertheless, diseases flares, that significantly contributes to…
Abstract Number: 120 • 2017 ACR/ARHP Annual Meeting
Patients with Rheumatoid Arthritis Have Higher Lifetime Professional and Non-Professional Exposure to Silica Dust Particles Compared to General Population
Luca Semerano^1,2,3, Catherine Cavalin^4,5,6, Odile Macchi^4,7, Sara El Rharras³, Mylene Petit³, Patrice Decker^8,9, Emma Andre¹⁰, Paul André Rosental^4,11 and Marie-Christophe Boissier¹², ¹UMR 1125, Inserm, Bobigny, France, ²EA4222, University of Paris 13, Sorbonne Paris Cité, Bobigny, France, ³Service de Rhumatologie, Assistance Publique – Hôpitaux de Paris (AP-HP) Groupe hospitalier Avicenne - Jean Verdier – René Muret, Bobigny, France, ⁴SILICOSIS project, ERC Advanced Grant, Centre for European Studies, Sciences Po, Paris, France, ⁵Centre for Employment and Labour Studies (CNAM), Noisy-le-Grand, France, ⁶Laboratory for Interdisciplinary Evaluation of Public Policies (LIEPP, Sciences Po, Paris), Paris, France, ⁷Centre for Historical Research, CNRS-EHESS, Paris, France, ⁸Li2P, University of Paris 13, Sorbonne Paris Cité, Bobigny, France, ⁹UMR 1125, INSERM, Bobigny, France, ¹⁰UMR1125, Inserm, Bobigny, France, ¹¹National Institute for Demographic Studies (INED), Paris, France, ¹²74 rue Marcel Cachin, INSERM, Bobigny, France
Background/Purpose: Occupational exposure to silica dust has been associated with increased risk of developing ACPA positive Rheumatoid arthritis (RA)1,2,3. Little is known about non-occupational exposure,…
Abstract Number: 1447 • 2017 ACR/ARHP Annual Meeting
Smoking Reduces Efficacy of Biologics Differently By Target Cytokines in Rheumatoid Arthritis
Kentaro Kuzuya¹, Yukihiko Saeki², Jun Hashimoto³, Shirou Oshima⁴, Masato Matsushita⁵, Souichirou Tuji⁴, Yoshinori Harada⁶, Maiko Yoshimura⁶, Satoru Teshigawara⁶ and Hidetoshi Matsuoka⁴, ¹Rheumatology and Allegology, Osaka-Minami Medical Ctr, Kawachinagano, Japan, ²Dept of Clinical research, Osaka-Minami Medical Ctr, Osaka, Japan, ³Rheumatology/Orthopaedics, Osaka-Minami Medical Ctr, Kawachinagano, Japan, ⁴Division of Rheumatology, Osaka-Minami Medical Ctr, Osaka, Japan, ⁵Rheumatology, Osaka-Minami Medical Ctr, Osaka, Japan, ⁶Osaka-Minami Medical Ctr, Kawachinagano, Japan
Background/Purpose: Biologiccs (Bio) have shown outstanding efficacy and became one of the most effective drugs in the treatment of RA. However, several issues remain, including…
Abstract Number: 987 • 2016 ACR/ARHP Annual Meeting
Pesticide Exposure and Risk of Rheumatoid Arthritis in Licensed Male Pesticide Applicators in the Agricultural Health Study
Armando Meyer¹, Dale Sandler², Laura Beane-Freeman³, Jonathan Hoffman⁴ and Christine G. Parks⁵, ¹Occupational and Environmental Health Branch, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil, ²Epidemiology Branch, NIH/NIEHS, Research Triangle Park, NC, ³Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute,, Bethesda, MD, ⁴3Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, ⁵Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC
Background/Purpose: We investigated associations between specific pesticides and RA in a cohort of licensed male pesticide applicators/farmers in the Agricultural Health Study (AHS). Of 30,316…
Abstract Number: 1214 • 2015 ACR/ARHP Annual Meeting
Rheumatoid Arthritis in Female Spouses in the Agricultural Health Study: Associations with Pesticides and Other Farm Exposures
Christine G. Parks¹, Jane Hoppin², Karen H. Costenbader³ and Dale Sandler⁴, ¹Epidemiology Branch, National Institute of Environmental Health Science, Research Triangle Park, NC, ²Biological Sciences, North Carolina State University, Raleigh, NC, ³Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Epidemiology Branch, NIH/NIEHS, Research Triangle Park, NC
Background/Purpose: Farming has been associated with rheumatoid arthritis (RA), but the role of pesticides is not known. We examined associations between RA, pesticides and other…
Abstract Number: 348 • 2014 ACR/ARHP Annual Meeting
Smoking Status Is Associated with Inflammatory Cytokine Profile and Disease Activity: Decreased Inflammation and Disease Improvement with Smoking Cessation?
Jeremy Sokolove¹, Harlan Sayles², Catriona Wagner³, Lauren J. Lahey¹, Geoffrey M. Thiele⁴, William H. Robinson¹, Andreas Reimold⁵, Gail S. Kerr⁶, Grant W. Cannon⁷ and Ted R. Mikuls², ¹VA Palo Alto Healthcare System and Stanford University, Palo Alto, CA, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ³VA Palo Alto Heatlh Care System and Stanford University, Palo Alto, CA, ⁴Internal Medicine, Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁵Rheumatology, Dallas VA and Univ of TX Southwestern Med Ct, Dallas, TX, ⁶Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ⁷Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT
Background/Purpose: Cigarette smoking is a risk factor for RA and has been associated with increased disease severity and lower rates of disease remission. We examined…
Abstract Number: 1072 • 2013 ACR/ARHP Annual Meeting
Gene-Environment Interaction Between HLA-DRB1 Shared Epitope and Occupational Textile Dust Exposure In The Risk Of ACPA-Positive Rheumatoid Arthritis In Female Patients: Evidence From The Malaysian Epidemiological Investigation Of Rheumatoid Arthritis Case-Control Study
Chun Lai Too^1,2, Nor Asiah Muhamad¹, Leonid Padyukov³, Lars Alfredsson⁴, Camilla Bengtsson⁵, Lars Klareskog⁶ and Shahnaz Murad⁷, ¹Institute for Medical Research, Jalan Pahang.Kuala Lumpur, Malaysia, Kuala Lumpur, Malaysia, ²Karolinska Institutet. Department of Medicine. Stockholm, Sweden, Stockholm, Sweden, ³Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, ⁴Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden, ⁵Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁶Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁷Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia
Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease with interacting genetic and environmental factors contributing to its etiology. In this study, we investigated…
Abstract Number: 72 • 2012 ACR/ARHP Annual Meeting
Relationships Between Air Pollution and Presence of Rheumatoid Arthritis-Related Autoantibodies in Individuals without Rheumatoid Arthritis: Studies of the Etiology of Rheumatoid Arthritis
Ryan W. Gan¹, Kevin D. Deane², Gary O. Zerbe³, Michael H. Weisman⁴, Jane H. Buckner⁵, P. K. Gregersen⁶, Ted R. Mikuls⁷, James R. O'Dell⁸, Richard M. Keating⁹, V. Michael Holers¹⁰ and Jill M. Norris¹, ¹Epidemiology, Colorado School of Public Health, Aurora, CO, ²Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ³Biostatistics and Informatics, Colorado School of Public Health / University of Colorado Anschutz Medical Campus, Aurora, CO, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Benaroya Research Institute at Virginia Mason, Seattle, WA, ⁶Genomics and Human Genetics, Feinstein Institute Medical Research and North Shore-Long Island Jewish Health System, Manhasset, NY, ⁷Internal Medicine, Omaha VA and University of Nebraska Medical Center, Omaha, NE, ⁸Dept of Internal Medicine, Univ of Nebraska Med Ctr, Omaha, NE, ⁹Rheumatology Section, The University of Chicago, Chicago, IL, ¹⁰Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Rheumatoid arthritis (RA) is characterized by the presence of circulating autoantibodies, which can be predictive of future RA development in currently unaffected individuals. …

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