Abstract Number: 1830 • 2018 ACR/ARHP Annual Meeting
Role of BMP2 in Entheseal Bone Formation in Inflammatory Arthritis
Background/Purpose: Spondyloarthritis (SpA) is common, with a prevalence of ~1% in the United States. Patients with SpA suffer from pain and disability due to inflammation…Abstract Number: 2397 • 2018 ACR/ARHP Annual Meeting
The Impact of Adalimumab on Growth in Patients with Pediatric Enthesitis-Related Arthritis
Background/Purpose: Children with one or more subtypes of juvenile idiopathic arthritis, such as enthesitis-related arthritis (ERA), often exhibit growth impairments. The purpose of the analysis…Abstract Number: 639 • 2017 ACR/ARHP Annual Meeting
Clinical and Sonographic Analysis of Patients with Psoriasis without Musculoskeletal Complaints. Preeliminary Results of a Prospective Study: The PRE-Psa Cohort
Background/Purpose: Early diagnosis in psoriatic arthritis (PsA) is mandatory in order to initiate early therapy and prevent disability. Around 20% of patients with Psoriasis (PsO)…Abstract Number: 661 • 2017 ACR/ARHP Annual Meeting
Normal Human Enthesis Contains a Resident Population of γδT-Cells
Background/Purpose: Recent animal studies have suggested that γδT-cells accumulate at enthesis, secrete IL-17 and are responsible for driving the spondyloarthritis (SpA) phenotype resulting from IL-23…Abstract Number: 3037 • 2016 ACR/ARHP Annual Meeting
Calprotectin Is Highly Upregulated in Inflamed Axial Entheses in SKG Mice
Background/Purpose: SKG mice exhibit features of spondyloarthropathy (SpA) and inflammatory bowel disease (IBD). Their SpA-like phenotype is induced by a beta-glucan, curdlan, via the Dectin-1…Abstract Number: 1978 • 2016 ACR/ARHP Annual Meeting
Differential Pattern of Doppler Signals at Lower Extremity Entheses of Healthy Children
Background/Purpose: Musculoskeletal ultrasound (MSUS) can enhance the clinical assessment of the pediatric enthesis. Doppler signals in particular are considered a sign of pathology but may…Abstract Number: 2742 • 2016 ACR/ARHP Annual Meeting
How Are Enthesitis, Dactylitis and Nail Involvement Measured and Reported in Recent Clinical Trials of Psoriatic Arthritis (PsA)? a Systematic Literature Review
Background/Purpose: Enthesitis, dactylitis and nail involvement are part of the core set of domains to be reported in trials of PsA. However, no specific instruments…Abstract Number: 201 • 2015 ACR/ARHP Annual Meeting
Innate Lymphoid Cells Are Present at Normal Human Enthesis Providing a Potential Mechanism for Spondyloarthropathy Pathogenesis
Background/Purpose: The pathogenesis of murine spondyloarthropathy (SpA) has been intimately linked to the presence of IL-23 responsive, innate like lymphocytes at peripheral and spinal enthesis.…Abstract Number: 2418 • 2015 ACR/ARHP Annual Meeting
Pediatric Enthesitis-Related Arthritis: Variation in Disease Characteristics and Treatments Among 5 Large Centers
Background/Purpose: We aimed to compare the clinical features and treatments of children with Enthesitis-related arthritis (ERA) from 5 pediatric rheumatology centers in order to determine…Abstract Number: 2594 • 2014 ACR/ARHP Annual Meeting
Differences in Localization and Activity of the Entheseal Involvement Between Non-Radiographic and Radiographic Axial Spondyloarthritis By the Ultrasound Assessment
Background/Purpose Inflammatory involvement of peripheral enthesis belongs to an important sign of spondyloarthritis (SpA). It may occur in patients with long-term as well as newly…Abstract Number: 1917 • 2014 ACR/ARHP Annual Meeting
IL-23 Expression and Activation of Autophagy in Synovium and PBMCs of HLA-B27 Positive Patients with Ankylosing Spondylitis
Background/Purpose: IL-23 may play a key role in the pathogenesis of ankylosing spondylitis (AS). Some studies describe indeed increased serum levels of IL-23 in AS…Abstract Number: 141 • 2014 ACR/ARHP Annual Meeting
Prevalence of Subclinical Enthesopathy in Asymptomatic First Degree Relatives of Patients with Spondyloarthritis
Background/Purpose There are no studies evaluating enthesis involvement detected by US in relatives of spondyloarthritis (SpA) patients. Objectives: 1) To evaluate and compare the prevalence…Abstract Number: 140 • 2014 ACR/ARHP Annual Meeting
Are Entheses Ultrasound Findings Similar in Axial Spa Patients and in Athletes?
Background/Purpose Spondyloarthritis (SpA) are characterized by inflammatory and structural changes in the entheses (enthesitis). However, enthesitis is not only observed in SpA and can also…