Abstracts tagged "endothelial cells and skin"

Abstract Number: 1172 • 2015 ACR/ARHP Annual Meeting
Single Cell Sequencing of Non-Lesional Non-Sun Exposed Skin from SLE Patients with Proteinuria Supports Widespread Endothelial Activation
Robert Clancy¹, Evan Der², Kemal Akat³, Anna R. Broder⁴, H. Michael Belmont⁵, Peter M. Izmirly⁶, Beatrice Goilav⁷, Thomas Tuschl³, Chaim Putterman⁸ and Jill P. Buyon¹, ¹Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Rockefeller University, New York, NY, ⁴Rheumatology-Forchheimer 701N, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, ⁵New York University School of Medicine, New York, NY, ⁶Rheumatology, NYU School of Medicine, New York, NY, ⁷Division of Nephrology, Children's Hospital at Montefiore, Bronx, NY, ⁸Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Given the widespread vasculopathy present in SLE, endothelial cell activation in the renal tubulointerstitium in lupus nephritis (LN) may be accompanied by similar activation…

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