Abstracts tagged "endothelial cells and large vessel vasculitis"

Abstract Number: 2933 • 2017 ACR/ARHP Annual Meeting
The Microvascular Niche Instructs Pathogenic T Cells in Medium and Large Vessel Vasculitis
Cornelia M. Weyand¹, Zhenke Wen², Yi Shen², Gerald Berry³, Joyce Liao⁴ and Jorg Goronzy⁵, ¹Medicine: Immunology and Rheumatology, Stanford University, Stanford, CA, ²Medicine: Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ³Pathology, Stanford University School of Medicine, Stanford, CA, ⁴Byers Eye Institute at Stanford, Stanford University, Palo Alto, CA, ⁵Medicine/Division of Immunology & Rheumatology, Stanford University School of Medicine, Stanford, CA
Background/Purpose: Adventitial microvascular networks (vasa vasora) control the access to the wall structure of medium and large arteries and thus guard the immune privilege of…
Abstract Number: 3141 • 2015 ACR/ARHP Annual Meeting
Endothelial Cells Regulate Proinflammatory T Cell Responses in Large Vessel Vasculitis Via NOTCH-NOTCH Ligand Interactions
Zhenke Wen¹, Hui Zhang¹, Joyce Liao², Gerald Berry³, Lindsy J. Forbess⁴, Michael Weissman⁵, Jorg Goronzy¹ and Cornelia M. Weyand⁶, ¹Medicine: Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ²Byers Eye Institute at Stanford, Stanford University, Palo Alto, CA, ³Pathology, Stanford University School of Medicine, Stanford, CA, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁶Medicine, Stanford University School of Medicine, Stanford, CA
Background/Purpose: In large vessel vasculitis (LVV), inflammatory infiltrates typically accumulate within the mural layers of the aorta and its major branches and are composed of…

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