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Abstracts tagged "endothelial cells and fibrosis"

  • Abstract Number: 1710 • 2017 ACR/ARHP Annual Meeting

    Down-Regulation of microRNA-126 in Scleroderma Microvascular Endothelial Cells Enhances the Transition of Endothelial to Mesenchymal Cells (Endo-MT) Induced By TGFβ through Down-Regulating PI3/Akt Signaling Pathway By Targeting PIK3R2

    Yongqing Wang1, Shadia Nada2, Nezam Altorok2 and Bashar Kahaleh2, 1University of Toledo, Toledo, OH, 2Medicine/Rheumatology, University of Toledo, Toledo, OH

    Background/Purpose: The accumulation of myofibroblasts in fibrotic tissue plays an important role in the pathogenesis of scleroderma (SSc) fibrosis. Recent studies have shown that myofibroblasts…
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ACR Pediatric Rheumatology Symposium 2020

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