Abstracts tagged "endothelail cells"

Abstract Number: 1433 • ACR Convergence 2021
Endothelium-protective, Histone-neutralizing Properties of the Polyanionic Agent Defibrotide
Hui Shi¹, Alex Gandhi¹, Stephanie Smith¹, Qiuyu Wang¹, Diane Chiang¹, Srilakshmi Yalavarthi¹, Ramadan Ali², Chao Liu¹, Gautam Sule¹, Eliza Pei-Suen Tsou¹, Yu Zuo¹, Yogendra Kanthi³, Jiandie Lin¹, James Morrissey¹ and Jason Knight¹, ¹University of Michigan, Ann Arbor, MI, ²University of Michigan, Ann Arobr, MI, ³NHLBI, NIH, Bethesda, MD
Background/Purpose: Neutrophil-mediated activation of the endothelium plays a role in the pathogenesis of diverse disease states ranging from autoimmunity to cancer to COVID-19. Neutralization of…

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Abstracts tagged "endothelail cells"

Endothelium-protective, Histone-neutralizing Properties of the Polyanionic Agent Defibrotide