Abstracts tagged "Eicosanoids"

Abstract Number: 0060 • ACR Convergence 2021
Lipidomic Profiling Identifies Different Expression of Oxylipins Between Synovial Tissue and Plasma of Patients with Rheumatoid and Psoriatic Arthritis
Abha Singh¹, Jessica Murillo Saich², Roxana Coras³, Julio Ramirez⁴, Eric Chang², Raquel Celis⁵, Aaron Armando², Oswald Quehenberger², Arthur Kavanaugh², Juan D Cañete⁶ and Monica Guma⁷, ¹University of California San Diego, San Diego, CA, ²University of California San Diego, La Jolla, CA, ³University of California San Diego/Department of Medicine, Autonomous University of Barcelona, San Diego, CA, ⁴Arthritis Unit, Rheumatology Department, Hospital Clinic and IDIBAPS, Barcelona, Spain, ⁵Hospital Clinic and IDIBAPS, Barcelona, Spain, ⁶Rheumatology Department, Hospital Clinic, Barcelona, Spain, ⁷University of California San Diego/San Diego VA Healthcare Service/Department of Medicine, Autonomous University of Barcelona, La Jolla, CA
Background/Purpose: Oxylipins are bioactive lipids derived from polyunsaturated fatty acids (PUFAs) that modulate inflammation. Oxylipins derived from n-6 PUFA precursors, such as arachidonic acid (AA),…