Abstracts tagged "Early Rheumatoid Arthritis"

Abstract Number: 2296 • 2013 ACR/ARHP Annual Meeting
Are SDAI50 and DAS28 Response Measures Comparable In Early Rheumatoid Arthritis Patients?
Mohammed Omair¹, Edward C. Keystone², Juan Xiong³, Gilles Boire⁴, Janet E. Pope⁵, J. Carter Thorne⁶, Carol A. Hitchon⁷, Boulos Haraoui⁸, Diane Tin⁹, Deborah Weber³, Vivian P. Bykerk² and Pooneh Akhavan², ¹Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ²Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ³Mount Sinai Hospital, Toronto, ON, Canada, ⁴Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁵St Joseph Health Care, London, ON, Canada, ⁶Southlake Regional Health Centre, Newmarket, ON, Canada, ⁷Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ⁸Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ⁹The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada
Background/Purpose: An essential element of treat to target strategy is adjusting therapy in the absence of achieving a target response by 12 wk. A DDAS28…
Abstract Number: 1368 • 2013 ACR/ARHP Annual Meeting
The Effect Of Vitamin D On Early Rheumatoid Arthritis: A Retrospective Cohort Analysis
Faye A H Cooles¹, Arthur G Pratt^2,3,4, Wan-Fai Ng^3,5, Terry J Aspray³ and John D Isaacs², ¹Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom, ²Institute of Cellular Medicine (Musculoskeletal Research Group), NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, ³Musculoskeletal Directorate, The Freeman Hospital, Newcastle upon Tyne, United Kingdom, ⁴Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ⁵Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle upon Tyne, United Kingdom
Background/Purpose: There is increasing evidence that vitamin D has immunoregulatory properties in autoimmunity. In established rheumatoid arthritis (RA) there appears to be an inverse association…
Abstract Number: 329 • 2013 ACR/ARHP Annual Meeting
Health-Related Quality Of Life In Early Psoriatic Arthritis In Comparison With Early Rheumatoid Arthritis. A 5-Year Follow-Up Report From The Swedish Early Psoriatic Arthritis Registry and The Swedish Early Intervention In RA Registry
Lars Törnqvist¹, Tomas Husmark², Ulla R. C. Lindqvist³, Gerd-Marie Alenius⁴, Per Larsson⁵, Annika Teleman⁶, Mats Geijer⁷, Lars Erik Kristensen⁸, Ingrid Thyberg⁹ and Elke Theander¹⁰, ¹Department of Rheumatology, Skåne University Hospital Malmö, Lund University, Sweden, Malmö, Sweden, ²Department of Rheumatology, Falu Hospital, Falun, Sweden, ³Department of Medical Sciences, Rheumatology, University Hospital, Uppsala university, Uppsala, Sweden, ⁴Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, ⁵Dept of Rheumatology, Karolinska University Hospital, Stockholm, Sweden, ⁶Department of Rheumatology, Spenshult Hospital, Oskarstrom, Sweden, ⁷Skåne University Hospital, Lund, Center for Medical Imaging and Physiology, Lund, Sweden, ⁸Rheumatology, Skåen University Hospital, Lund University, Lund, Sweden, ⁹Rheumatology, Linköping University Hospital, Linkoping, Sweden, ¹⁰Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden
Background/Purpose: Studies on early psoriatic arthritis (ePsA) are still rare and data on health related quality of life (HRQoL) in ePsA are lacking completely. To…
Abstract Number: 2270 • 2013 ACR/ARHP Annual Meeting
US Guided Treat-To-Target Approach In Early RA: Implications For Uncoupling Of Disease Activity and Structural Damage
Yasser El Miedany¹, Maha El Gaafary², Sally Youssef³ and Annie Nasr⁴, ¹Rheumatology, Medway Hospital, Gillingham, United Kingdom, ²Community, Environmental and Occupational Medicine, Ain Shams University, Cairo, Egypt, ³Rheumatology & Rehabilitation, Ain Shams University, Cairo, Egypt, ⁴Radiology, Ain Shams University, Cairo, Egypt
Background/Purpose: To assess the relationship between inflammation and joint destruction in RA patients who have not responded clinically to treatment using Musculoskeletal US as a…
Abstract Number: 1343 • 2013 ACR/ARHP Annual Meeting
Are There Differences Between Young and Older Onset Early Rheumatoid Arthritis and Does This Impact Outcomes? An Analysis From The Canadian Early Arthritis Cohort
Michael Arnold¹, Vivian P. Bykerk², Gilles Boire³, Boulos Haraoui⁴, Carol A. Hitchon⁵, J. Carter Thorne⁶, Edward Keystone⁷ and Janet E. Pope⁸, ¹Medicine/Rheumatology, University College Dublin, Ireland, Dublin, Ireland, ²Divison of Rheumatology, Hospital for Special Surgery, New York, NY, ³Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology, Institut de Rhumatologie de Montréal, Montreal, QC, Canada, ⁵Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ⁶Southlake Regional Health Centre, Newmarket, ON, Canada, ⁷Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, University of Toronto, Toronto, ON, Canada, ⁸Medicine, Divsion of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
Background/Purpose: To determine the impact of age on disease and remission in early rheumatoid arthritis (ERA). Methods: Data from the Canadian Early Arthritis Cohort (CATCH)…
Abstract Number: L14 • 2013 ACR/ARHP Annual Meeting
For Remission Induction with Glucocorticoid Bridging, Methotrexate Monotherapy Is As Effective As a Combination with Other Dmards, with Fewer Reported Side Effects: 4 Month Primary Outcome of Carera, a Randomized Induction Strategy and Treat to Target Trial in Early RA
Diederik De Cock¹, Sabrina Meyfroidt¹, Johan Joly², Kristien Van der Elst^2,3, Rene Westhovens^4,5 and Patrick Verschueren^2,6, ¹Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Leuven, Belgium, ²University Hospitals Leuven on behalf of the CareRA Study Group, Leuven, Belgium, ³Skeletal Biology and Engineering Research Center, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium, ⁴University of Leuven, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration; Rheumatology, University Hospital Leuven, Leuven, Belgium, ⁵Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Leuven, Belgium, KU Leuven, Leuven, Belgium, ⁶1Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Leuven, Belgium
Background/Purpose: Intensive combination therapy with glucocorticoids (GCs) is the most favorable treatment to benefit from the window of opportunity in early Rheumatoid Arthritis (eRA) but…
Abstract Number: 2275 • 2013 ACR/ARHP Annual Meeting
Responsiveness Of The Outcomes Measures In Rheumatology Clinical Trials Initiative’s Preliminary Flare Questions To Detect Flares Within Patients In The Canadian Early Arthritis Cohort
Vivian P. Bykerk^1,2, Karen Visser³, Ernest Choy⁴, Clifton O. Bingham III⁵, Daming Lin², Juan Xiong⁶, Gilles Boire⁷, Boulos Haraoui⁸, Carol A. Hitchon⁹, Janet E. Pope¹⁰, J. Carter Thorne¹¹, Diane Tin¹², Edward C. Keystone¹³, Susan J. Bartlett¹⁴, - CATCH Investigators¹⁵ and - OMERACT Flare Working Group¹⁶, ¹Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, ²Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁵Rheumatology, Johns Hopkins University, Baltimore, MD, ⁶Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁷Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁸Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ⁹Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹⁰St Joseph Health Care, London, ON, Canada, ¹¹Southlake Regional Health Centre, Newmarket, ON, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹⁴Clinical Epidemiology, McGill University, Montreal, QC, Canada, ¹⁵Canadian Collaboration, Toronto, ON, Canada, ¹⁶International Collaboration, Baltimore, MD
Background/Purpose: OMERACT (OM) recently developed preliminary flare questions (PFQs) that capture domains important to patients (pts) to identify a flare of RA1. Whether these change…
Abstract Number: 1329 • 2013 ACR/ARHP Annual Meeting
Physician Global Assessment At Three Months Is Strongly Predictive Of Remission At 12 Months In Early Rheumatoid Arthritis. Results From The Canadian Early Arthritis Cohort
Tommy Choy¹, Vivian P. Bykerk², Gilles Boire³, Boulos Haraoui⁴, Carol A. Hitchon⁵, J. Carter Thorne⁶, Edward C. Keystone⁷ and Janet E. Pope⁸, ¹Medicine/Rheumatology, University of Western Ontario, London, ON, Canada, ²Divison of Rheumatology, Hospital for Special Surgery, New York, NY, ³Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology, Institut de Rhumatologie de Montréal, Montreal, QC, Canada, ⁵Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ⁶Southlake Regional Health Centre, Newmarket, ON, Canada, ⁷Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁸Medicine, Divsion of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
Background/Purpose: To determine predictors of 1-year remission in early rheumatoid arthritis (ERA) using baseline and 3 months data. Methods: The Canadian Early Arthritis Cohort (CATCH)…
Abstract Number: 2257 • 2013 ACR/ARHP Annual Meeting
Symptom Complexes At The Beginning Of Rheumatoid Arthritis: A Qualitative Exploration In At Risk Individuals and In New Patients Prior To Diagnosis
Rebecca J Stack¹, Lilian H.D. van Tuyl², Maurits Sloots³, Lotte A. van de Stadt³, Wijnanda Hoogland³, Bertha Matt³, Christian D Mallen⁴, Rumandeep Tiwana¹, Karim Raza¹ and Dirkjan van Schaardenburg³, ¹Centre for Translational Inflammation Research, University of Birmingham, Birmingham, United Kingdom, ²Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ³Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ⁴Arthritis Research UK Primary Care Centre, University of Keele, Keele, United Kingdom
Background/Purpose: To achieve better prediction of the development of rheumatoid arthritis (RA) a EULAR study group recommended identification and assessment of symptoms in those with…
Abstract Number: 1304 • 2013 ACR/ARHP Annual Meeting
Anti-Carbamylated Antibody Positivity Is Associated With More Severe Radiological Progression In Patients With Recent Onset ACPA Negative Rheumatoid Arthritis: Results From The Norfolk Arthritis Register (NOAR)
Jenny H. Humphreys¹, Suzanne M. Verstappen¹, Kimme L. Hyrich², Tarnya Marshall³, Anne Barton^4,5, René E.M. Toes⁶, Leendert A. Trouw⁶ and Deborah P. Symmons^4,7, ¹Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, ²Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ³Rheumatology, Norfolk and Norwich University Hospitals Trust, Norwich, United Kingdom, ⁴Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ⁵NIHR Manchester Musculoskeletal BRU, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, ⁶Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁷NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, United Kingdom
Background/Purpose: Autoantibodies against carbamylated proteins (anti-CarP) have been associated with more severe radiological damage in patients with rheumatoid arthritis (RA), including in a small subgroup…
Abstract Number: 2259 • 2013 ACR/ARHP Annual Meeting
Does a Ratingen Score Of ≥ 3 At Disease Onset Define RA In ACR/EULAR 2010 Criteria Negative Patients?
Ruediger Mueller¹, Toni Kaegi¹, Sarah Haile² and Johannes von Kempis¹, ¹Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ²Clinical Trials Unit, Kantonsspital St. Gallen, St. Gallen, Switzerland
Background/Purpose: A EULAR task force has recently selected an evidence and consensus based definition of erosive disease defining rheumatoid arthritis (RA) in patients who do…
Abstract Number: 1312 • 2013 ACR/ARHP Annual Meeting
A Multi-Biomarker Disease Activity Score Correlates With Radiographic Progression In Early Rheumatoid Arthritis: Results From a Randomized Trial
Karen Hambardzumyan¹, Rebecca Bolce², Scott E. Cruickshank³, Eric H. Sasso², David Chernoff², Kristina Forslind⁴, Saedis Saevarsdottir⁵, Ingemar F. Petersson⁶, Pierre Geborek⁷, Sofia Ernestam⁸ and Ronald F van Vollenhoven⁹, ¹ClinTRID, the Karolinska Institute, Stockholm, Sweden, ²Crescendo Bioscience Inc., South San Francisco, CA, ³Scott E. Cruickshank and Associates, Inc., Santa Barbara, CA, ⁴Department of Medicine, Karolinska Institute, Stockholm, Department of Medicine, Karolinska Institute,, Stockholm, Sweden, ⁵Karolinska Institutet, Stockholm, Sweden, ⁶Lund University, Lund, Sweden, ⁷Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, ⁸Huddinge Hospital, Karolinska University Hospital, Huddinge, Sweden, ⁹ClinTRID, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: In early rheumatoid arthritis (eRA), predictors of radiographic damage would be useful for optimal targeting of therapy. It has been suggested that combining various…
Abstract Number: 1970 • 2013 ACR/ARHP Annual Meeting
The Utility Of Fluorescence Optical Imaging For Detecting Clinically Silent Synovitis Of The Hands and Wrists
Yogan Kisten¹, Noémi Györi², Hamed Rezaei³, Anna Karlsson¹, Carolina Romanus², Ronald van Vollenhoven⁴ and Erik af Klint⁵, ¹Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute,Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Stockholm, Sweden, ²Unit for Clinical Therapy Research Inflammaroty Diseases (ClinTRID) Department of Medicine, the Karolinska Insitute, Stockholm, Sweden, ³Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ⁴Unit for Clinical Research Therapy. Inflammatory Diseases (ClinTrid), Karolinska Institute, Stockholm, Sweden, ⁵Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The rheumatology clinic of the Karolinska University Hospital, Stockholm, Sweden
Background/Purpose: The detection of subclinical synovial inflammation (“silent synovitis”) would be of critical importance for the detection of rheumatoid arthritis (RA) in its earliest pathophysiological…
Abstract Number: 1138 • 2013 ACR/ARHP Annual Meeting
Tuberculin Skin Test and Booster Phenomenon In a Rheumatoid Arthritis Population. Differences Between Early and Established Disease
Lorena Perez-Barbosa¹, David Vega-Morales², Janett Carmen Luzmilla Riega-Torres¹, Octavio Ilizaliturri-Guerra¹ and Mario Alberto Garza-Elizondo¹, ¹Early Arthritis Clinic, Rheumatology Service, Hospital Universitario, Monterrey, Mexico, ²Rheumatology, Hospital Universitario UANL, Monterrey, Mexico
Background/Purpose: Tuberculosis (TB) remains a major global health problem. Chronic inflammation in Rheumatoid Arthritis (RA) and the use of immunosuppressive drugs, increase the risk of…
Abstract Number: 1956 • 2013 ACR/ARHP Annual Meeting
The Effect Of Initial Methotrexate Therapy On Cartilage Composition In Early Rheumatoid Arthritis: Follow-Up With Biochemical MRI Of Finger Cartilage
Dr. Philipp Sewerin¹, Dr. Falk Miese², Dr. Hans-Jörg Wittsack³, Dr. Stefan Vordenbäumen¹, Dr. Christoph Schleich⁴, Prof. Dr. Gerald Antoch³, Prof. Dr. Matthias Schneider⁵ and Prof. Dr. Benedikt Ostendorf¹, ¹Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, ²Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, ³Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, ⁴Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, ⁵Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany
Background/Purpose: To test for initial status and subsequent recovery of cartilage glycosaminoglycane content in metacarpophalangeal joints (MCP) in patients with early rheumatoid arthritis (eRA) undergoing…

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