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Abstracts tagged "Early Rheumatoid Arthritis"

  • Abstract Number: 2914 • 2014 ACR/ARHP Annual Meeting

    The Clinical and Radiographic Course of Early Undifferentiated Arthritis Under Treatment Is Not Dependent on the Amount of Erosions at Diagnosis. Results from the Swiss Prospective Observational Cohort

    Ruediger Mueller1, Toni Kaegi2, Sarah Haile3 and Johannes von Kempis4, 1Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Division of Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 3Division of Biostatistics, Institute for Social and Preventive Medicine,, University of Zurich, Switzerland, Zurich, Switzerland, 4Rheumatology, St. Gallen Hospital, CH- 9007 St.Gallen, Switzerland

    Background/Purpose To analyse whether early arthritis patients who do not fulfil the ACR/EULAR 2010 classification criteria for rheumatoid arthritis (RA) have a different course of…
  • Abstract Number: 1847 • 2014 ACR/ARHP Annual Meeting

    Effect of Disease Duration on Clinical Outcomes in Moderate Rheumatoid Arthritis Patients Treated with Etanercept Plus Methotrexate in the Preserve Study

    Josef Smolen1, David Collier2, Annette Szumski3, Heather Jones4 and Lisa Marshall5, 1PsAID taskforce, EULAR, Zurich, Switzerland, 2Amgen, Inc., Thousand Oaks, CA, 3Specialty Care, Pfizer Inc., Collegeville, PA, 4Inflammation & Immunology, Pfizer Inc., Collegeville, PA, 5Inflammation Immunology Disease Group, Pfizer Inc., Collegeville, PA

    Background/Purpose Previous studies evaluating various treatment strategies indicate that disease duration is a key determinant of outcomes in rheumatoid arthritis (RA). While data suggest that…
  • Abstract Number: 406 • 2014 ACR/ARHP Annual Meeting

    The Utility of HLA-DR Genotypification As a Complementary Tool to Discriminate Undifferentiated and Rheumatoid Arthritis Patients in Early Arthritis

    Fernando Dal Pra1, Gustavo Citera2, Margarita Landi3, Christian A. Waimann4, Luis Alejandro Cayetti2, Sergio Paira5, Federico Ceccatto6, Teresita Alvarellos7, Luciana Mas7, Josefina Marcos8, Mercedes García8, A Salas8, Alejandro Martinez9, Rafael Chaparro10, Oscar Luis Rillo11, Edson Veloso12, Ricardo V. Juárez13, Maria Elena Crespo14, Antonio Catalán Pellet15, Anastasia Secco15, Lucila Marino16 and V Martire15, 1Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, 2Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 3Rheumatology, Instituto Rehabilitacion Psicofisica, Buenos Aires, Argentina, 4Rheumatology, Hospital Olavarria, Olavarria, Argentina, 5Section of Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, 6Rheumatology, Hospital Jose María Cullen, Santa Fé, Argentina, 7Laboratorio de Histocompatibilidad, Hospital Privado Centro Medico De Córdoba, Cordoba, Argentina, 8HIGA San Martín, La Plata, Argentina, 9Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 10Rheumatology, Hospital Gral. de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 11Rheumatology Section, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 12Sanatorio y Universidad Adventista Del Plata, Entre Rios, Argentina, 13Rheumatology Section, Hospital Señor del Milagro, Salta, Argentina, 14Hospital Señor Del Milagro, Salta, Argentina, 15Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, 16Rheumathology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina

    Background/Purpose: Only half of patients with undifferentiated arthritis (UA) will progress to rheumatoid arthritis (RA) after two years of follow-up.  Particular human leukocyte antigens class…
  • Abstract Number: 2259 • 2013 ACR/ARHP Annual Meeting

    Does a Ratingen Score Of ≥ 3 At Disease Onset Define RA In ACR/EULAR 2010 Criteria Negative Patients?

    Ruediger Mueller1, Toni Kaegi1, Sarah Haile2 and Johannes von Kempis1, 1Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, 2Clinical Trials Unit, Kantonsspital St. Gallen, St. Gallen, Switzerland

    Background/Purpose: A EULAR task force has recently selected an evidence and consensus based definition of erosive disease defining rheumatoid arthritis (RA) in patients who do…
  • Abstract Number: 1312 • 2013 ACR/ARHP Annual Meeting

    A Multi-Biomarker Disease Activity Score Correlates With Radiographic Progression In Early Rheumatoid Arthritis: Results From a Randomized  Trial

    Karen Hambardzumyan1, Rebecca Bolce2, Scott E. Cruickshank3, Eric H. Sasso2, David Chernoff2, Kristina Forslind4, Saedis Saevarsdottir5, Ingemar F. Petersson6, Pierre Geborek7, Sofia Ernestam8 and Ronald F van Vollenhoven9, 1ClinTRID, the Karolinska Institute, Stockholm, Sweden, 2Crescendo Bioscience Inc., South San Francisco, CA, 3Scott E. Cruickshank and Associates, Inc., Santa Barbara, CA, 4Department of Medicine, Karolinska Institute, Stockholm, Department of Medicine, Karolinska Institute,, Stockholm, Sweden, 5Karolinska Institutet, Stockholm, Sweden, 6Lund University, Lund, Sweden, 7Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, 8Huddinge Hospital, Karolinska University Hospital, Huddinge, Sweden, 9ClinTRID, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: In early rheumatoid arthritis (eRA), predictors of radiographic damage would be useful for optimal targeting of therapy.  It has been suggested that combining various…
  • Abstract Number: 1970 • 2013 ACR/ARHP Annual Meeting

    The Utility Of Fluorescence Optical Imaging For Detecting Clinically Silent Synovitis Of The Hands and Wrists

    Yogan Kisten1, Noémi Györi2, Hamed Rezaei3, Anna Karlsson1, Carolina Romanus2, Ronald van Vollenhoven4 and Erik af Klint5, 1Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute,Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Stockholm, Sweden, 2Unit for Clinical Therapy Research Inflammaroty Diseases (ClinTRID) Department of Medicine, the Karolinska Insitute, Stockholm, Sweden, 3Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, 4Unit for Clinical Research Therapy. Inflammatory Diseases (ClinTrid), Karolinska Institute, Stockholm, Sweden, 5Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The rheumatology clinic of the Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: The detection of subclinical synovial inflammation (“silent synovitis”) would be of critical importance for the detection of rheumatoid arthritis (RA) in its earliest pathophysiological…
  • Abstract Number: 1138 • 2013 ACR/ARHP Annual Meeting

    Tuberculin Skin Test and Booster Phenomenon In a Rheumatoid Arthritis Population. Differences Between Early and Established Disease

    Lorena Perez-Barbosa1, David Vega-Morales2, Janett Carmen Luzmilla Riega-Torres1, Octavio Ilizaliturri-Guerra1 and Mario Alberto Garza-Elizondo1, 1Early Arthritis Clinic, Rheumatology Service, Hospital Universitario, Monterrey, Mexico, 2Rheumatology, Hospital Universitario UANL, Monterrey, Mexico

    Background/Purpose: Tuberculosis (TB) remains a major global health problem.   Chronic inflammation in Rheumatoid Arthritis (RA) and the use of immunosuppressive drugs, increase the risk of…
  • Abstract Number: 1956 • 2013 ACR/ARHP Annual Meeting

    The Effect Of Initial Methotrexate Therapy On Cartilage Composition In Early Rheumatoid Arthritis: Follow-Up With Biochemical MRI Of Finger Cartilage

    Dr. Philipp Sewerin1, Dr. Falk Miese2, Dr. Hans-Jörg Wittsack3, Dr. Stefan Vordenbäumen1, Dr. Christoph Schleich4, Prof. Dr. Gerald Antoch3, Prof. Dr. Matthias Schneider5 and Prof. Dr. Benedikt Ostendorf1, 1Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 3Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 4Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, 5Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany

    Background/Purpose: To test for initial status and subsequent recovery of cartilage glycosaminoglycane content in metacarpophalangeal joints (MCP) in patients with early rheumatoid arthritis (eRA) undergoing…
  • Abstract Number: 1034 • 2013 ACR/ARHP Annual Meeting

    The Part Of Function (Health assessment Questionnaire) In The SF-6D and EQ-5D Utility Measures Varies Over Time In Early Arthritis (ESPOIR cohort): Questionable Validity Of Deriving Quality Adjusted Life Years From HAQ

    Cécile Gaujoux-Viala1, Anne-Christine Rat2, Kossar Hosseini3, Rene-Marc Flipo4, Francis Guillemin3 and Bruno Fautrel5, 1EA 2415, Montpellier I University, Nîmes University Hospital, Rheumatology Department, Nîmes, France, 2Université de Lorraine, Nancy, F-54000, France; Inserm, CIC-EC CIE6, Nancy, F-54000, France; CHU de Nancy, Clinical Epidemiology and Evaluation Department, Nancy, F-54000, France; CHU de Nancy, Rheumatology department, Nancy, France, 3CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, 4Rheumatology, University Hospital Lille, Lille, France, 5Paris 6 – Pierre et Marie Curie University; AP-HP, Rheumatology, Pitié-Salpêtrière Hospital, - GRC-UPMC 08 – EEMOIS, Paris, France

    Background/Purpose: There is growing emphasis on the cost-effectiveness of treating early arthritis (EA). As few studies directly record the utility measures needed for economic analyses,…
  • Abstract Number: 1960 • 2013 ACR/ARHP Annual Meeting

    Combination Of Magnetic Resonance Imaging-Proven Osteitis With 2010 RA Classification Criteria Improves The Diagnostic Probability Of Early Rheumatoid Arthritis Whose Disease Duration Less Than 6 Months

    Mami Tamai1,2, Junko Kita3, Yoshikazu Nakashima4, Ayako Nishino4, Takahisa Suzuki4, Yoshiro Horai4, Akitomo Okada5, Tomohiro Koga6, Shin-ya Kawashiri4,7, Naoki Iwamoto4, Kunihiro Ichinose4, Kazuhiko Arima7, Satoshi Yamasaki8, Hideki Nakamura4, Tomoki Origuchi9, Masataka Uetani10, Aya Fukushima10, Kiyoshi Aoyagi7, Katsumi Eguchi11 and Atsushi Kawakami4, 1Center for Health & Community Medicine, Nagasaki University, Nagasaki, Japan, 2Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 3Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 4Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 5Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, 6Departments of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 7Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 8Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan, 9Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 10Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 11Sasebo City General Hospital, Sasebo, Nagasaki, Japan

    Background/Purpose: In the articles describing the 2010 rheumatoid arthritis (RA) classification criteria , it is stated that additional evidence of joint injury from imaging techniques such…
  • Abstract Number: 870 • 2013 ACR/ARHP Annual Meeting

    How To Predict That Early Arthritis Without Rheumatoid Factor and ACPA Becomes Rheumatoid Arthritis According To ACR/EULAR 2010 After a 3-Years Follow-Up? Results From The Espoir Cohort

    Gaël Mouterde1, Cédric Lukas2, Nathalie Rincheval3, Alain Saraux4, Philippe Dieude5 and Bernard Combe6, 1Rheumatology, Montpellier 1 University, Lapeyronie Hospital, Montpellier, France, 2Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, 3Institut Universitaire de Recherche Clinique, Montpellier, France, 4Department of rheumatology and unit of immunology (EA 2216), CHU Brest et Université Bretagne Occidentale, Brest, France, 5Rheumatology, Rheumatology departement & INSERM U699, Paris Diderot university, APHP, Bichat hospital, Paris, France, 6Rheumatology, Lapeyronie Hospital, Montpellier I university, Montpellier, France

    Background/Purpose: To describe disease course of patients without rheumatoid factor (RF) and anti-citrullinated protein auto-antibodies (ACPA) in an inception cohort of early arthritis patients. To determine…
  • Abstract Number: 1962 • 2013 ACR/ARHP Annual Meeting

    The Value Of the  2010 ACR/EULAR Rheumatoid Arthritis Classification Criteria For The Prognosis Of Early Arthritis: Evaluation Of Erosion Development With Ultrasonography

    Nevsun Inanc1, Fatma Alibaz-Oner2, Meryem Can3, Pamir Atagündüz2 and Haner Direskeneli2, 1Department of Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 2Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 3Department of Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: The 2010  ACR/EULAR Rheumatoid Arthritis(RA) classification criteria was developed to diagnose the early arthritis patients who will progress destructive disease and to start  early…
  • Abstract Number: 833 • 2013 ACR/ARHP Annual Meeting

    Cardiovascular Diseases In Rheumatoid Arthritis: Can Early Treatment With Disease-Modifying Antirheumatic Drugs Alter The Risk?

    Rishi Desai1, Jaya Rao2, Richard Hansen3, Gang Fang4, Matthew Maciejewski5 and Joel Farley4, 1Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 2Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 3Harrison School of Pharmacy, Auburn University, Auburn, AL, 4University of North Carolina, Chapel Hill, NC, 5Duke University, Durham, NC

    Background/Purpose: Atherosclerosis is known to be accelerated in rheumatoid arthritis (RA) patients resulting in an increased cardiovascular (CV) risk. Structural damage to joints occurs aggressively…
  • Abstract Number: 1820 • 2013 ACR/ARHP Annual Meeting

    Assessing 24-Hour Physical (In)Activity and Sleep In People With Early Rheumatoid Arthritis

    Christopher Feehan1, Eric C. Sayre2, Erin Carruthers2 and Lynne M. Feehan3, 1Medicine, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Centre of Canada, Richmond, BC, Canada, 3Physical Therapy, Arthritis Research Centre of Canada and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: For people with inflammatory arthritis, the health benefits of physical activity (PA) and negative impact of sedentary lifestyle are clear. However, it is unclear…
  • Abstract Number: 799 • 2013 ACR/ARHP Annual Meeting

    Clinical and Radiological Outcomes Of Two Years Remission Steered Treatment In Early Arthritis Patients

    L. Heimans1, K.V.C. Wevers-de Boer1, G. Akdemir1, H.K Ronday2, T.H.E. Molenaar3, J. H. L. M. Van Groenendael4, A.J. Peeters5, I. Speyer6, G. Collee7, P.B. de Sonnaville8, B.A. Grillet9, T.W.J. Huizinga1 and C.F. Allaart1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Haga Hospital, The Hague, Netherlands, 3Dept of Rheumatology, Groene Hart Hospital, Gouda, Netherlands, 4Franciscus Hospital, Roosendaal, Netherlands, 5Rheumatology, Reinier de Graaf Gasthuis, Delft, Netherlands, 6Rheumatology, Bronovo Hospital, Den Haag, Netherlands, 7MCH, The Hague, Netherlands, 8Department of Rheumatology, Admiraal de Ruyter hospital, Goes, Netherlands, 9Department of Rheumatology, Zorgsaam Hospital, Terneuzen, Netherlands

    Background/Purpose: To evaluate outcomes after 2 years of remission steered therapy in early arthritis patients. Methods: 610 patients with early rheumatoid or undifferentiated arthritis (UA)…
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