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Abstracts tagged "drug treatment and mouse model"

  • Abstract Number: 3082 • 2015 ACR/ARHP Annual Meeting

    Nanogel Based Delivery of an Inhibitor of Calcium/ Calmodulin- Dependent Protein Kinase 4 Suppresses Experimental Autoimmune Encephalomyelitis and Lupus-like Disease in Mice

    Kotaro Otomo1, Tomohiro Koga2, Nobuya Yoshida3, Masayuki Mizui4, Christina Kriegel5, Tarek Fahmy6 and George C. Tsokos3, 1Rheumatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2Department of Rheumatology, Unit of Translational Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, 3Division of Rheumatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 4Department of Nephrology, Osaka University Graduate School of Medicine, Osaka, Japan, 5Department of Biomedical Engineering, Yale University, New Heaven, CT, 6Biomedical and Chemical Engineering, Yale University, New Heaven, CT

    Background/Purpose: Treatment of autoimmune diseases is still based on the use of general immunosuppressive drugs which invariably cause severe side effects. This fact has compelled…
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ACR Pediatric Rheumatology Symposium 2020

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