Abstracts tagged "drug treatment and clinical trials"

Abstract Number: 2520 • 2019 ACR/ARP Annual Meeting
Treatment of SLE Patients with the Immunoproteasome Inhibitor KZR-616: Results from the First 3 Cohorts of an Open-Label Phase 1b Dose Escalation Trial
Richard Furie¹, Darrin Bomba ², Maria Dall'Era ³, Amber Khan ⁴, Miguel Soneira ⁴, Janet Anderl ², Jinhai Wang ², Christopher Kirk ² and Niti Goel ⁵, ¹Northwell Health, Great Neck, NY, ²Kezar Life Sciences, SOUTH SAN FRANCISCO, CA, ³University of California, San Francisco, San Francisco, CA, ⁴Accurate Clinical Research, Houston, TX, ⁵Kezar Life Sciences, Duke University School of Medicine, South San Francisco, CA
Background/Purpose: Nonspecific proteasome inhibitors, eg, bortezomib (BTZ), target both the constitutive and immuno- proteasome and are approved for the treatment of multiple myeloma. While BTZ…

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Abstracts tagged "drug treatment and clinical trials"

Treatment of SLE Patients with the Immunoproteasome Inhibitor KZR-616: Results from the First 3 Cohorts of an Open-Label Phase 1b Dose Escalation Trial