ACR Meeting Abstracts

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Abstracts tagged "Drug toxicity"

  • Abstract Number: 0337 • ACR Convergence 2024

    Characterization of Statin Induced Myopathy in the Hospital Setting

    Olivia Yang1, KUMAR VENKAT2, Jeffery Durbin3 and Scott Kubomoto1, 1Riverside Community Hospital, Riverside, CA, 2Voluntary Clinical Associate Professor of Medicine -UCRSOM, Riverside, California, IRVINE, CA, 3HCA Healthcare Physicians Services Group, Brentwood, TN

    Background/Purpose: Adverse effects of statin use involve the muscle and related rhabdomyolysis. Known risk factors for rhabdomyolysis include female sex, older age, Asian race, hypothyroidism,…
  • Abstract Number: 1243 • ACR Convergence 2024

    A Patient-Focused Program for Using Steroids Wisely

    John Stone1, Michelle Petri2, Jeffrey Gelfand3, Camille Kotton4, Jane McDowell5, George Papaliodis6, meredith Marinaro7, Matt Wilkinson8, Walter Lentfert9 and Martha Stone10, 1Massachusetts General Hospital , Harvard Medical School, Concord, MA, 2Johns Hopkins University School of Medicine, Timonium, MD, 3University of California, San Francisco, San Francisco, CA, 4Harvard Medical School, Boston, MA, 5Queens University Belfast, Belfast, Ireland, 6Massachusetts General Hospital, Boston, MA, 7Novartis, Hartford, CT, 8UpThereEverywhere, London, United Kingdom, 9UpThereEverywhere, Wilmington, NC, 10Steritas, LLC, CONCORD, MA

    Background/Purpose: Patients have no comprehensive, curated resource on steroid use to facilitate effective collaboration in their own care. Consequently, truly shared decision making around steroid…
  • Abstract Number: 0363 • ACR Convergence 2024

    Comparative Risk of Demyelinating Diseases Among Patients on TNF-Alpha Inhibitors: A Cohort Study Using the TriNetX Database

    Rafal Ali1, Yurilu Gonzalez Moret2, Roua Hussein3 and Fabian Rodriguez4, 1Jefferson Einstein Philadelphia, Lansdale, PA, 2Jefferson Einstein Philadelphia, Philadelphia, PA, 3Al-Mustansiriyah University/ college of medicine, New York, NY, 4Jefferson Einstein Hospital, Philadelphia, PA

    Background/Purpose: TNF-alpha inhibitors are widely used in the field of rheumatology and have been linked to various possible adverse events, including demyelinating diseases. This association…
  • Abstract Number: 1949 • ACR Convergence 2024

    Implementation of Pharmacist-Led Comprehensive Medication Management for Puerto Ricans with Rheumatic Diseases

    Ileana Rodriguez Nazario, Kyle Melin and Luis Vilá, University of Puerto Rico Medical Sciences Campus, San Juan, PR

    Background/Purpose: Comprehensive Medication Management (CMM) is a standardized intervention provided by clinical pharmacists that uses subjective and objective patient information to create a plan to…
  • Abstract Number: 0376 • ACR Convergence 2024

    Preliminary Results of the Ondansetron Pre-medication Trial in Juvenile Idiopathic Arthritis: A Pragmatic Randomized Controlled Trial Nested in the CAPRI Registry

    Gaelle Chedeville1, Heinrike Schmeling2, Jean-Philippe Proulx-Gauthier3, Michelle Batthish4, Jean Jacques De Bruycker5, Brian Feldman6, Roberta A Berard7, Roxana Bolaria8, Amieleena Chhabra9, Lily Lim10, Adam Huber11, Matthew Berkowitz12, Thomas Loughin12 and Jaime Guzman13, and CAPRI Registry Investigators, 1The Montreal Children's Hospital, Montreal, QC, Canada, 2University of Calgary, Calgary, AB, Canada, 3CHU de Quebec - Universite Laval, Quebec, QC, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5UNIVERSITY OF MONTREAL, Montreal, QC, Montreal, QC, Canada, 6Division of Rheumatology, The Hospital for Sick Children; Departments of Pediatrics and Medicine, Faculty of Medicine; The Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 7London Health Sciences Centre, London, ON, Canada, 8Victoria Arthritis Center, Victoria, BC, Canada, 9University of British Columbia, Penticton, BC, Canada, 10University of Manitoba, Winnipeg, MB, Canada, 11IWK Health Centre, Halifax, NS, Canada, 12Simon Fraser University, Burnaby, BC, Canada, 13University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: About 50% of children with Juvenile Idiopathic Arthritis (JIA) receiving methotrexate (MTX) develop MTX intolerance with severe anticipatory nausea/vomiting and avoidance behaviors. Intolerance often…
  • Abstract Number: 1986 • ACR Convergence 2024

    Disease Flare Following Immune Checkpoint Inhibition in Patients with Cancer and Preexisting Vasculitis

    Juan Sevillano1, Yixuan Zhou2, Juan Ruiz3, Noha Abdel-Wahab4 and Maria Suarez-Almazor1, 1MD Anderson Cancer Center, Houston, TX, 2Baylor College of Medicine, Houston, 3MD Anderson, Houston, TX, 4University of Texas MD Anderson Cancer Center, houston, TX

    Background/Purpose: Immune checkpoint inhibitors (ICI) are effective therapies for patients with cancer, but they often cause immune-related adverse events (irAE). There is limited data on…
  • Abstract Number: 0439 • ACR Convergence 2024

    Contraception Counseling and Contraception Use Among SLE and RA/JIA Patients at a Public Medical Center in Los Angeles: Investigating Teratogenic Medication Use and Language Preferences

    Laura Kobashigawa1, Cassidy Hernandez-Tamayo2, Katherine Ruddy3, Melissa Wilson2 and Leanna Wise4, 1University of Southern California/Los Angeles General Medical Center, Pasadena, CA, 2Keck School of Medicine of USC, Los Angeles, CA, 3University of Southern California/ Los Angeles General Medical Center, Los Angeles, CA, 4LAC+USC/Keck Medicine of USC, Pasadena, CA

    Background/Purpose: Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)/juvenile idiopathic arthritis (JIA) frequently impact women of reproductive age. Management of these patients is particularly important…
  • Abstract Number: 1997 • ACR Convergence 2024

    Features of interleukin-1 and interleukin-6 Inhibitor (IL-1i/IL-6i) Related Severe Delayed Adverse Reactions in Subjects with or Without Reaction-risk Associated HLA-DRB1*15

    Vivian E Saper1, Kazutoyo Osoegawa1, Ruud Verstegen2, Marcelo A Fernandez Vina1 and Lu Tian1, and Drug Hypersensitivity Consortium, 1Stanford University, Stanford, CA, 2The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: A very serious drug-related adverse event is reported with inhibitors of IL-1 and IL-6 (IL-1i/IL6i). This reaction scores as drug reaction with eosinophilia and…
  • Abstract Number: 0441 • ACR Convergence 2024

    A Qualitative Improvement Project to Incorporate the Mycophenolate Risk Evaluation and Mitigation Strategies in an Academic Lupus Clinic

    Dahima Cintron1, Jennifer Rogers2, Rebecca Sadun1, Mithu Maheswaranathan3, Kai Sun1, Jayanth Doss1, Lisa Criscione-Schreiber3 and Megan Clowse4, 1Duke University, Durham, NC, 2Duke, Durham, NC, 3Duke University School of Medicine, Durham, NC, 4Duke University, Chapel Hill, NC

    Background/Purpose: Mycophenolate Mofetil/Mycophenolic acid (MMF) is an immunosuppressant used to treat SLE. Due to the teratogenic effects of MMF, the FDA recommended universal risk evaluation…
  • Abstract Number: 2000 • ACR Convergence 2024

    Induction of Systemic Inflammatory Diseases with Dupilumab Therapy

    Jeanne Tisseau des Escotais1, Camille Taille2, Julie Merindol3, Matthieu Groh4, Perrine SMETS5, Amel Boudjemaa6, Alexandra Audemard7, Nabil Belfeki8, Philippe Bonniaud9, Chloe Comarmond10, Isabelle DELACROIX11, Charlotte Descours12, Lucile Grange13, Paul Legendre14, Nihal Martis15, Thomas Moulinet16, Béatrice Walls17, Laurent Chouchana1 and Benjamin Terrier18, 1Cochin, Paris, France, 2Bichat Hospital, Paris, France, 3Internal Medicine Department, University Hospital of Nice, Côte d'Azur University, Nice, Provence-Alpes-Côte d'Azur, France., Nice, France, 4Foch, Suresnes, France, 5Clermont Ferrand University Hospital - National reference center for autoimmune disease, Internal Medicine, Clermont-Ferrand, France, 6CHU créteil, Créteil, France, 7Tours, Tours, France, 8CH Melun, Melun, France, 9Centre de Référence Constitutif des Maladies Pulmonaires Rares de l'Adulte, Service de Pneumologie et Soins Intensifs Respiratoires, Centre Hospitalo-Universitaire de Dijon-Bourgogne, Dijon, France, 10Lariboisière University Hospital, Paris, France, 11CHI créteil, Créteil, France, 12CH Tours, Tours, France, 13CH Saint-Etienne, Saint-Etienne, France, 14Service Médecine Interne et Polyvalente, Centre Hospitaliers Le Mans, Le Mans, France, 15CH Nice, Nice, France, 16CHRU de Nancy, Vandœuvre-lès-Nancy, France, 17Paris, Paris, France, 18Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France

    Background/Purpose: Dupilumab is a monoclonal antibody directed against the alpha subunit of the interleukin (IL)-4 receptor, blocking interleukin (IL)-4 and IL-13 signaling. It is approved…
  • Abstract Number: 0537 • ACR Convergence 2024

    Evaluating the Usage of Janus Kinase Inhibitors in Rheumatology and Its Impact on Cardiovascular Risk

    Knkush Hakobyan1, Talar Acob2, Mesrop Aleksanyan3, Tigran Kakhktsyan3, Omar Jumaah3 and Sajina Prabhakaran4, 1Capital Health medical center, Princeton, NJ, 2College of medicine-university of Baghdad, Plainsboro Township, NJ, 3Capital Health Medical Center, Trenton, 4Capital health Rheumatology specialists, Newtown, PA

    Background/Purpose: Janus kinase (JAK) inhibitors have been widely used in treatingrheumatological conditions like rheumatoid arthritis and psoriatic arthritis. Despite theirefficacy, there are concerns regarding major…
  • Abstract Number: 2004 • ACR Convergence 2024

    Rheumatic Complications Post-CAR-T Cell Therapy. Experience of a Single Center

    Jose Alfredo Gomez-Puerta1, Ana Monegal1, Andrés Ponce2, Pilar Peris3, Nuria Martínez4, Valentin Ortiz-Maldonado4, Ana Triguero4, Carlos Fernández de larrea4, Julio Delgado4, Raimon Sanmartí Sala1 and Manuel Juan5, 1Rheumatology Department, Hospital Clinic of Barcelona, Barcelona, Spain, 2Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, 3Rheumatology Department, Hospital Clínic de Barcelona, Barcelona, Spain, 4Haematology Department, Hospital Clinic of Barcelona, Barcelona, Spain, 5Immunology Department, Hospital Clinic of Barcelona, Barcelona, Spain

    Background/Purpose: CAR-T cell therapy is a promising treatment for a range of systemic autoimmune diseases such as systemic lupus erythematosus, systemic sclerosis, and antisynthetase syndrome,…
  • Abstract Number: 0606 • ACR Convergence 2024

    Choice of Biologic Immunotherapy for Psoriasis or Psoriatic Arthritis Not Associated with Risk of Major Adverse Cardiac Events

    Bonit Gill1, Jack Geiger1, Jean Liew2, Michael Putman3 and Shikha Singla1, 1Medical College of Wisconsin, Milwaukee, WI, 2Boston University, Boston, MA, 3The Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Individuals with psoriasis or psoriatic arthritis (PsO/PsA) have an elevated risk ofmajor adverse cardiac events (MACE), which include congestive heart failure (CHF), myocardialinfarction (MI),…
  • Abstract Number: 2121 • ACR Convergence 2024

    Increased Fracture Rates in Patients Continuing Methotrexate After Methotrexate-associated Lower Limb Insufficiency Fractures: A Retrospective Follow-up Study

    Roba Ghossan1, OLIVIER FOGEL2, Christian Roux1 and Karine Briot1, 1COCHIN HOSPITAL, PARIS, France, 2AP-HP, Paris, France

    Background/Purpose: Spontaneous  lower limb insufficiency fractures (LLIF) described under prolonged exposure to low-dose methotrexate are often bilateral, multiple, and recurrent. They share a common pathognomonic…
  • Abstract Number: 0675 • ACR Convergence 2024

    Hydroxychloroquine Induced Cardiomyopathy: A Biopsy Proven Case Series

    Swetapadma Tripathy1, Davina Chen2, Lanny DiFranza3 and Bibi Ayesha4, 1Montefiore Medical Center, Forest Hills, NY, 2Montefiore Medical Center, New Rochelle, NY, 3Montefiore Medical Center, New York City, NY, 4Montefiore Medical Center, Metuchen, NJ

    Background/Purpose: Cardiomyopathy is a rare, life-threatening adverse effect of hydroxychloroquine (HCQ) use. There is a paucity in literature regarding treatment and prognosis in these cases. The aim…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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