Abstracts tagged "Drug therapy and systemic sclerosis"

Abstract Number: 694 • 2012 ACR/ARHP Annual Meeting
Nilotinib (Tasigna™) in the Treatment of Early Diffuse Systemic Sclerosis: A Single Group, Open Label Pilot Clinical Trial
Jessica K. Gordon¹, Morgana L. Davids², Kamini Doobay², Cynthia Magro³, Horatio F. Wildman⁴, Stephen L. Lyman⁵, Mary K. Crow⁶ and Robert F. Spiera¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Medicine/Rheumatology, Hospital for Special Surgery, New York, NY, ³Dermatopathology, Weill-Cornell Medical Center, New York, NY, ⁴Dermatology, Weill-Cornell Medical Center, New York, NY, ⁵Research, Hospital for Special Surgery, New York, NY, ⁶Department of Medicine, Hospital for Special Surgery, New York, NY
Background/Purpose: Tyrosine kinase inhibitors (TKI) which selectively antagonize c-abl and PDGFR have been shown in preclinical models to decrease fibrosis. TKIs are therapies of interest…

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Abstracts tagged "Drug therapy and systemic sclerosis"

Nilotinib (Tasigna™) in the Treatment of Early Diffuse Systemic Sclerosis: A Single Group, Open Label Pilot Clinical Trial