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Abstracts tagged "DMOAD and osteoarthritis"

  • Abstract Number: L16 • ACR/ARHP Annual Meeting 2018

    Intra-Articular TPX-100 in Knee Osteoarthritis: Robust Functional Response at 6 and 12 Months Is Associated with Increased Tibiofemoral Cartilage Thickness

    Dawn McGuire1, Neil Segal2, Samy Metyas3, Hans Richard Barthel4, Meghan Miller5, David Rosen5 and Yoshi Kumagai5, 1Orthotrophix, Incorporated, Oakland, CA, 2Physical Medicine and Rehabilitation, University of Kansas Medical Center, Kansas City, KS, 3Medvin Clinical Research, Covina, CA, 4Barthel Clinic, Santa Barbara, CA, 5OrthoTrophix, Incorporated, Oakland, CA

    Background/Purpose: TPX-100, a peptide derived from Matrix Extracellular Phosphoglycoprotein (MEPE), has been shown to induce articular cartilage regeneration after cartilage injury in animal models. A…
  • Abstract Number: 907 • ACR/ARHP Annual Meeting 2012

    Use of Patient Preferences to Inform the Development of Disease Modifying Drugs for Osteoarthritis

    Liana Fraenkel1, Charles Cunningham2, Gillian A. Hawker3 and Lisa Suter4, 1Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, 2McMaster University, Hamilton, ON, Canada, 3Women's College Research Institute, University of Toronto, Toronto, ON, Canada, 4Medicine, Rheumatol, TAC S541, Yale University, New Haven, CT

    Background/Purpose: Considerable efforts are currently being directed at developing robust and efficient trial designs to study the efficacy of disease modifying drugs (DMOADs) for osteoarthritis…

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