Abstracts tagged "DMARDs and rheumatoid arthritis (RA)"

Abstract Number: 1468 • 2013 ACR/ARHP Annual Meeting
Reasons For Discontinuation Of Biologic Agents In Rheumatoid Arthritis Patients
Eric Elkin¹, Martin J. Bergman², Tripthi Kamath³, Sarika Ogale³, Adam Turpcu³, Kristin King⁴, Jae Oh⁴, Monarch Shah¹ and Max I. Hamburger⁵, ¹ICON Clinical Research, San Francisco, CA, ²Taylor Hospital, Ridley Park, PA, ³Genentech, South San Francisco, CA, ⁴ICON Late Phase and Outcomes Research, San Francisco, CA, ⁵Rheumatology Associates, Melville, NY
Background/Purpose: Results from randomized controlled trials indicate that about one-third of rheumatoid arthritis (RA) patients initially treated with anti-TNF agents do not respond, show a…
Abstract Number: 1422 • 2013 ACR/ARHP Annual Meeting
Efficacy and Safety Of a Novel Disease-Modifying Antirheumatic Drug, Iguratimod, As Add-On Therapy For Patients With Rheumatoid Arthritis
Daisuke Kobayashi¹, Satoshi Ito², Akira Murasawa¹, Ichiei Narita³ and Kiyoshi Nakazono¹, ¹Niigata Rheumatic Center, Shibata, Japan, ²Niigata Rheumatic Center, Niigata, Japan, ³Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Background/Purpose: Iguratimod is a newly-developed disease-modifying antirheumatic drug (DMARD) that was approved in Japan in September 2012. It has been reported to suppress tumor necrosis…
Abstract Number: 484 • 2013 ACR/ARHP Annual Meeting
Response To Biologic Disease-Modifying Anti-Rheumatic Drugs After Discontinuation Of Anti-Tumor Necrosis Factor Alpha Agents In Rheumatoid Arthritis Patients
Eric Elkin¹, Max I. Hamburger², Tripthi Kamath³, Sarika Ogale³, Adam Turpcu³, Jae Oh⁴, Kristin King⁴, Monarch Shah¹ and Martin J. Bergman⁵, ¹ICON Clinical Research, San Francisco, CA, ²Rheumatology Associates, Melville, NY, ³Genentech, South San Francisco, CA, ⁴ICON Late Phase and Outcomes Research, San Francisco, CA, ⁵Taylor Hospital, Ridley Park, PA
Background/Purpose: Rheumatoid arthritis (RA) patients who have failed an anti-TNF agent as their first biologic agent have the option of switching to a second aTNF…
Abstract Number: 203 • 2013 ACR/ARHP Annual Meeting
Belief In Self-Adjustability Of Medication Dosing Is Negatively Correlated With Medication Adherence In Patients With Rheumatoid Arthritis
Wenxin Sun¹, Dianne Carrol Tan Bautista², Xiaohui Xin³, Yu Ting Saw³, Wee Boon Tan³, Kanchanadevi Balasubramaniam³, Wan Pin Lee⁴, Steve Thein Htay Oo³, Yin Bun Cheung² and Julian Thumboo⁵, ¹Duke-NUS Graduate Medical School, Singapore, Singapore, ²Center for Quantitative Medicine, Office of Clinical Sciences, Duke-NUS Graduate Medical School, Singapore, Singapore, ³Academic Clinical Programme, Division of Medicine, Singapore General Hospital, Singapore, Singapore, ⁴Operation and Performance Management, Singapore General Hospital, Singapore, Singapore, ⁵Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore
Background/Purpose: Medication adherence in Rheumatoid Arthritis (RA) is reported to be generally low. This major problem needs to be addressed because it leads to reduced…
Abstract Number: 193 • 2013 ACR/ARHP Annual Meeting
Physician Variability In Rheumatoid Patients Not Receiving Biologics Or Non-Biologic Dmards: Implications For Quality Reporting
Dimitrios A. Pappas¹, Lang Chen², Leslie R. Harrold³, George W. Reed⁴, Joel M. Kremer⁵, Jeffrey D. Greenberg⁶ and Jeffrey R. Curtis⁷, ¹Department of Medicine, Division of Rheumatology, Columbia University, College of Physicians and Surgeons, New York, NY, ²Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³University of Massachusetts Medical School, Worcester, MA, ⁴Corrona, LLC., Southborough, MA, ⁵Center for Rheumatology, Albany Medical College, Albany, NY, ⁶Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, New York, NY, ⁷University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, AL
Background/Purpose: Current quality of care guidelines recommend that all patients with Rheumatoid Arthritis (RA) be treated with biologic and/or non-biologic (nb) DMARDs. However, some RA…
Abstract Number: 2636 • 2012 ACR/ARHP Annual Meeting
Understanding Why Treat-to-Target Strategies Are Difficult to Follow
Liana Fraenkel¹, Meaghan Cunningham² and Paul Falzer³, ¹Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, ²Medicine, Yale University School of Medicine, New Haven, CT, ³Medicine, VA Connecticut Healthcare System, New Haven, CT
Background/Purpose: Treat-to-target (T2T) refers to a set of decision strategies widely advocated for the optimal management of rheumatoid arthritis (RA). Despite considerable evidence that this…
Abstract Number: 387 • 2012 ACR/ARHP Annual Meeting
Medication Choices and Medication Survival in a National Multicentre Community Based Rheumatoid Arthritis Cohort
Lynden Roberts¹, Kathleen Tymms², Julien P. de Jager³, Geoffrey O. Littlejohn⁴, Hedley Griffiths⁵, Dave Nicholls⁶, Paul Bird⁷, Julie Hill⁸, Philip McCloud⁸, James C. Scott⁹, Jane Zochling¹⁰ and OPAL Consortium¹¹, ¹School of Medicine, James Cook University, Townsville, Australia, ²Canberra Rheumatology, Canberra, ACT, Australia, ³Suite 2, Osler House, Southport, Australia, ⁴Rheumatology, Monash Medical Center, Melbourne, Australia, ⁵Barwon Rheumatology Service, Geelong, Australia, ⁶Coast Joint Care, Maroochydore, Australia, ⁷Combined Rheumatology Practice, Sydney, Australia, ⁸Statistics, McCloud Consulting Group, Sydney, Australia, ⁹Medical Affairs, Roche Products Pty Limited, Sydney, Australia, ¹⁰Menzies Research Institute Tasmania, Hobart, Australia, ¹¹Melbourne, Australia
Background/Purpose: A sizeable body of high-quality research underpins our knowledge of the efficacy of various RA therapies. Outside the controlled environment of these clinical trials,…

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