Abstracts tagged "disease susceptibility and rheumatoid arthritis (RA)"

Abstract Number: 2715 • 2016 ACR/ARHP Annual Meeting
Genetic Variants in TNF, TNFRSF1A, and IL23R Are Associated with Risk of Ankylosing Spondylitis
Jacob Sode^1,2,3, Ulla Vogel⁴, Steffen Bank⁵, Paal Skytt Andersen⁶, Merete Lund Hetland⁷, Henning Locht², Niels H. H. Heegaard⁸ and Vibeke Andersen⁹, ¹Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark, ²Department of Rheumatology, Frederiksberg Hospital, Frederiksberg, Denmark, ³Department of Rheumatology, Skåne University Hospital, Lund, Sweden, ⁴National Research Centre for the Working Environment, Copenhagen, Denmark, ⁵Institute of Human Genetics, University of Aarhus, Aarhus, Denmark, ⁶Microbiology & Infection Control, Statens Serum Institut, Copenhagen S, Denmark, ⁷DANBIO Registry and Departments of Rheumatology, Rigshospitalet (Glostrup and Blegdamsvej), University of Copenhagen, Glostrup, Denmark, ⁸Department of Autoimmunology & Biomarkers, Statens Serum Institut, Copenhagen, Denmark, ⁹Odense University Hospital, OPEN (Odense Patient data Explorative Network), Odense, Denmark
Background/Purpose: The objective of this study was to evaluate single nucleotide polymorphisms (SNPs) involved in TNFα signaling, NF-κB activation, interferon-γ signaling, or pattern recognition receptor…

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