Abstracts tagged "Disease Activity"

Abstract Number: 2878 • 2015 ACR/ARHP Annual Meeting
Treating Axial Spondyloarthritis to Target: Influence of the Population Characteristics and Comorbidities in Reaching Ankylosing Spondylitis Disease Activity Score (ASDAS) Inactive Disease in a Cohort of Patients Treated with Tnfalpha Inhibitors Agents
Sara Monti, Veronica Codullo, Vittorio Grosso, Silvia Breda, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy
Background/Purpose: The treat to target strategy (T2T), aiming at inactive disease (ID), has become the recommended approach also in the field of axial-SpA (axSpA) (1). …
Abstract Number: 3185 • 2015 ACR/ARHP Annual Meeting
A Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach in the Clinical Care of Rheumatoid Arthritis Patients in the United States
Leslie Harrold^1,2, George W. Reed^1,2, J. Timothy Harrington³, Christine J. Barr¹, Katherine C. Saunders¹, Allan Gibofsky⁴, Eric M. Ruderman⁵, Tmirah Haselkorn⁶, Jeffrey D. Greenberg^1,7, Ani John⁶ and Joel M. Kremer⁸, ¹Corrona, LLC, Southborough, MA, ²University of Massachusetts Medical School, Worcester, MA, ³Joiner Associates, LLC, Madison, WI, ⁴Hospital for Special Surgery, New York, NY, ⁵Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Genentech, Inc, South San Francisco, CA, ⁷NYU School of Medicine, New York, NY, ⁸Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: We report the results of a cluster-randomized behavioral intervention trial designed to assess the impact of implementing a treat-to-target (T2T) approach vs usual care…
Abstract Number: 409 • 2015 ACR/ARHP Annual Meeting
Disease Activity, Disease Damage and Predictive Factors in Juvenile Onset Mixed Connective Tissue Disease – a Norwegian Nationwide Study
Siri Opsahl Hetlevik¹, Berit Flatø^1,2, Marite Rygg^3,4, Ellen Berit Nordal⁵ and Vibke Lilleby⁶, ¹Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, ²Department of Rheumatology, Oslo University Hospital, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, ³Department of Pediatrics, St Olav University Hospital, Trondheim, Norway, ⁴Department of Laboratory Medicine, Children's and Women's health, Norwegian University of Science and Technology, Trondheim, Norway, ⁵Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway, ⁶Rheumatology, Oslo University Hospital, Oslo, Norway
Background/Purpose: Mixed Connective Tissue Disease (MCTD) is a rare rheumatic disease with overlapping features from Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc) and Polymyositis. Juvenile…
Abstract Number: 620 • 2015 ACR/ARHP Annual Meeting
Evaluation of Patients from the Non-Biologic Arms of Inflammatory Arthritis Clinical Trials Identifies Several Predictors of Remission, As Well As, Distinct Responder Subgroups
Brian Tom¹ and Deborah P.M. Symmons², ¹Biostatistics Unit, Medical Research Council, Cambridge, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
Background/Purpose: The RA-MAP consortium is a UK flagship industry-academic partnership investigating clinical and biological predictors of disease outcome in patients with rheumatoid arthritis (RA). Methods:…
Abstract Number: 1027 • 2015 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Disease Activity Assessment Frequencies in Clinical Practices Do Not Support Treat-to-Target Care
David Sikes¹, James Bower², Drew Johnson³, J. Timothy Harrington², Rafia Khalil⁴, Edmund LaCour⁵, Michael Naarendorp⁶, Hillary Norton⁷ and Kathleen Thomas⁸, ¹Rheumatology, Florida Medical Clinic PA, Zephyrhills, FL, ²Joiner Associates LLC, Madison, WI, ³Crescendo Bioscience, Inc., South San Francisco, CA, ⁴Rafia Khalil Arthritis & Rheumatology Center, PC, Port Huron, MI, ⁵Dothan Medical Associates PC, Dothan, AL, ⁶Harlem Rhematology, LLC, New York, NY, ⁷Rheumatology, Santa Fe Rheumatology, Santa Fe, NM, ⁸Community Rheumatology, Noblesville, IN
Background/Purpose: Treat-to-Target (T2T) recommendations for rheumatoid arthritis (RA) care include standardized frequencies of disease activity (DA) assessment based on DA level. For this study, "on…
Abstract Number: 1691 • 2015 ACR/ARHP Annual Meeting
The Presence of Fibromialgia May Influence the Clinimetric Evaluation of Patients with Ankylosing Spondylitis, but Has No Impact on Disease Activity Assessment
Emilio Buschiazzo¹, Natalia Zamora², Fernando Andres Sommerfleck³, Romina Rojas Tessel⁴, Mariana Benegas⁵, Pablo Arturi^6,7, Maria Elena Crespo⁴, Emilce Schneeberger⁸ and Gustavo Citera², ¹Rheumatology, Hospital Sr Del Milagro, Salta, Argentina, ²Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ³Rheumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Hospital Sr Del Milagro, Salta, Argentina, ⁵Sanatorio Mitre, Buenos Aires, Argentina, ⁶Rheumatology, Instituto de Rehabilitacion Psicofisica and Fundacion Reumatologica Argentina, Buenos Aires, Argentina, ⁷Rheumatology, Hospital Italiano de La Plata, La Plata, Argentina, ⁸Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina
Background/Purpose: Fibromyalgia (FM) can be present concomitantly in patients with Ankylosing Spondylitis (AS). It may overestimate the evaluation of disease activity, resulting in more intensive…
Abstract Number: 2481 • 2015 ACR/ARHP Annual Meeting
Work Disability in a Cohort of Patients with Psoriatic Arthritis
Cecilia Zaffarana¹, Osvaldo Luis Cerda¹, Josefina Gallino Yanzi¹, Margarita Landi¹, Emilce Schneeberger¹, Ignacio Carrillo¹, María del Carmen Gonzalez Guzmán¹, Jose A Maldonado Cocco¹, Susana Gagliardi¹ and Gustavo Citera², ¹Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Rheumatology, Consultorios Reumatológicos Pampa, Buenos Aires, Argentina
Background/Purpose: Several studies showed that unemployment and work disability are high in patients with Psoriatic Arthritis (PsA). Te purpose of this study is to evaluate work…
Abstract Number: 2619 • 2015 ACR/ARHP Annual Meeting
Clinical Usefulness of Periodic Detection of Serum 14-3-3Î· for Predicting Efficacy of Tocilizumab in RA
Akira Sagawa¹, Takuya Isayama², Makoto Kaneda³, Yuan Gui⁴, Anthony Marotta⁵ and Jiro Arai², ¹Sagawa Akira Rheumatology Clinic, Sapporo, Japan, ²Medical and Biological Laboratories Co., Ltd., Ina, Japan, ³MBL Europe, Diegem, Belgium, ⁴Augurex Life Sciences Corp., North Vancouver, BC, Canada, ⁵1423 Dempsey Road, Augurex Life Sciences Corp., North Vancouver, BC, Canada
Background/Purpose: Serum 14-3-3η is a diagnostic marker for RA. Recent in vitro evidence indicates that it may play a casual role in the pathogenesis of…
Abstract Number: 2881 • 2015 ACR/ARHP Annual Meeting
Infliximab in Spondyloarthritis Patients: Utility of Drug Level Monitoring
Claudia Deaconu¹, Diana Mazilu², Laura Grosanu², Ioana Saulescu², Andreea Borangiu², Cecilia Gainaru³, Cosmin Constantinescu², Violeta Bojinca², Violeta Vlad¹, Andra Balanescu², Denisa Predeteanu², Ruxandra Ionescu² and Daniela Opris², ¹Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ²University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ³"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
Background/Purpose: Spondyloarthritides, a heterogeneous group of chronic, inflammatory disorders with overlapping organ and joint targeting, share the same therapeutic approach in regard to biological therapy.…
Abstract Number: 3206 • 2015 ACR/ARHP Annual Meeting
Inflammation on MRI in Sacroiliac-Joints and Spine Is Longitudinally Related to Disease Activity in Male but Not in Female Patients with Axial Spondyloarthritis: 2-Year Data from the DESIR Cohort
Victoria Navarro-Compán¹, Sofia Ramiro², Robert B. M. Landewé³, Maxime Dougados⁴, Corinne Miceli-Richard⁵, Pascal Richette⁶ and Désirée van der Heijde⁷, ¹Rheumatology, University Hospital La Paz, Madrid, Spain, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands, ⁴Université Paris René Descartes and Hôpital Cochin, Paris, France, ⁵Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France, ⁶Université Paris Diderot, UFR médicale, Paris, France; APHP Hôpital Lariboisière, Fédération de Rhumatologie and Inserm U1132, Hôpital Lariboisière, Paris, France, ⁷Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: In patients with axial spondyloarthritis (axSpA), clinical disease activity measures (DA) have been longitudinally related to radiographic progression. Interestingly, a gender disparity has been…
Abstract Number: 418 • 2015 ACR/ARHP Annual Meeting
Relationship of Race, Ethnicity, and Outcomes in Pediatric Localized Scleroderma: Possible Differences in Disease Activity
Kaveh Ardalan¹, Nicole Hershey¹, Jonathan Yabes², Kathryn S. Torok¹ and The CARRA Registry Investigators, ¹Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Pediatric localized scleroderma (LS) is an autoimmune skin and soft tissue disease that causes morbidity via progressive skin fibrosis and extracutaneous manifestations (ECMs), such…
Abstract Number: 666 • 2015 ACR/ARHP Annual Meeting
Disease Activity Indices and Body Mass Index: Cross-Sectional Analysis of a Large Psoriatic Arthritis Cohort
Umut Kalyoncu¹, Ozun BayndÄ±r¹, Barış Yılmazer¹, Ediz Dalkilic², Kenan Aksu¹, Mustafa Ferhat Oksuz¹, E.Figen Tarhan¹, Meryem Can¹, Orhan Kucuksahin¹, Gezmis Kimyon¹, Lutfi Akyol¹, Ahmet Mesut Onat¹, Bunyamin Kisacik¹, Abdulsamet Erden¹, Ahmet Omma¹, Duygu Ersozlu Bakirli¹, Cem Ozisler¹, Emel Gonullu¹, Seval Pehlevan¹, Dilek Solmaz¹, Muhammet Cinar¹, Gozde Cetin¹, Abdurrahman Tufan¹, Muge Aydin Tufan¹, Levent Kilic¹, Sukran Erten¹, Timucin Kasifoglu¹, Senol Kobak¹, Soner Senel¹, Servet Akar¹, Metin Ozgen¹, Esen Kasapoglu-Gunal¹, Veli Yazisiz¹, Sedat Yılmaz¹, Salim Donmez¹, Ä°smail Dogan¹, Hamide Kart Koseoglu¹, Funda Erbasan¹, Fatih Yildiz¹, Cemal Bes¹, Ayse Balkarli¹, Ali Sahin¹, Rıdvan Mercan¹, Fatoş Arslan¹, Atalay Dogru¹, Salih Pay¹, Sule Yavuz¹, Necati Cakir¹, Yasemin Kabasakal¹ and Sibel Z. Aydin¹, ¹PsART study group, Ankara, Turkey, ²Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey
Background/Purpose: Well known comorbidities of Psoriatic arthritis (PsA) such as cardiovascular disease, metabolic syndrome and diabetes mellitus are closely related with body mass index (BMI).…
Abstract Number: 1070 • 2015 ACR/ARHP Annual Meeting
CD 14(C-159T) Polymorphism and Soluble CD14 Are Associated with Increased Disease Activity and Nephritis in SLE
Sarit sekhar Pattanaik¹, Aditya kumar Panda², Rashmi ranjan Sahoo¹, Rina Tripathy³ and Bidyut kumar Das¹, ¹Medicine, SCB Medical College, Cuttack, India, ²Centre for Life science, Central University of Jharkand, Ranchi, India, ³Biochemistry, SCB Medical College, Cuttack, India
Background/Purpose: Cluster of differentiation 14 (CD14) plays an important role in innate immune system as a co-receptor in TLRs (2, 4, 7 and 9) signaling.…
Abstract Number: 1738 • 2015 ACR/ARHP Annual Meeting
Assessing the Validity of the Multi-Biomarker Disease Activity Assay in Patients with Psoriatic Arthritis
Tristan Boyd¹, Doquyen H. Huynh¹, P. Scott Eastman², Ferhan Qureshi³, Eric H. Sasso⁴, Rebecca J. Bolce⁴, Joshua Hillman⁵, David L. Boyle⁶ and Arthur Kavanaugh⁷, ¹Rheumatology, University of California San Diego, La Jolla, CA, ²Crescendo Bioscience, South San Francisco, CA, ³Crescendo Bioscience, Inc., South San Francisco, CA, ⁴Crescendo Bioscience Inc., South San Francisco, CA, ⁵Div of Rheum, UCSD School of Medicine, La Jolla, CA, ⁶Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA, ⁷University of California, San Diego School of Medicine, LaJolla, CA
Background/Purpose: Considerable heterogeneity across clinical domains of psoriatic arthritis (PsA) can make assessment of disease activity challenging. As a result, there has been interest in…
Abstract Number: 2487 • 2015 ACR/ARHP Annual Meeting
Clinical Practices Participating in a Quality Improvement Project Make Progress in Implementing Population Management
Erin Arnold¹, William Arnold¹, James Bower², Douglas Conaway³, J. Timothy Harrington², Drew Johnson⁴, James Mossell⁵, Joy Schechtman⁶ and Anne Winkler⁷, ¹Orthopedics and Rheumatology of the North Shore, Skokie, IL, ²Joiner Associates LLC, Madison, WI, ³Rheumatology/Medicine, Carolina Health Specialists, Myrtle Beach, SC, ⁴Crescendo Bioscience, Inc., South San Francisco, CA, ⁵Arthritis and Osteo Center of South Georgia, Tifton, GA, ⁶Sun Valley Arthritis Center LTD, Peoria, AZ, ⁷Rheumatology, Winkler Medical Practice LLC, Springfield, MO
Background/Purpose: Population management (PM) offers a promising approach to providing Treat-to-Target (T2T) care for rheumatoid arthritis (RA). PM depends on providing standardized, on-time disease activity…

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