Abstracts tagged "Disease Activity"

Abstract Number: 478 • 2015 ACR/ARHP Annual Meeting
Impact of Comorbidities on the Multi-Biomarker Disease Activity Test in Rheumatoid Arthritis Patients
Jeffrey R. Curtis¹, Jeffrey D. Greenberg², Leslie Harrold³ and J. Lynn Palmer⁴, ¹University of Alabama at Birmingham, Birmingham, AL, ²Corrona, LLC, Southborough, MA, ³Department of Medicine, UMass Memorial Medical Center, Worcester, MA, ⁴Corrona Research Foundation, Albany, NY
Background/Purpose: The multi-biomarker disease activity (MBDA) score [Vectra] has been evaluated in a number of settings, yet has only limited data evaluating whether it is…
Abstract Number: 679 • 2015 ACR/ARHP Annual Meeting
Patients with Psoriatic Arthritis and Oligoarthritic Subtype Report Higher Disease Burden Than Patients with a Polyarthritic Pattern – Data from the German Collaborative Arthritis Centres
Dörte Huscher¹, Katinka Albrecht², Sascha Bischoff², Katja Thiele², Frank Behrens³, Kathrin Fischer⁴, Ulrich von Hinüber⁵, Susanna Späthling-Mestekemper⁶, Siegfried Wassenberg⁷ and Angela Zink¹, ¹German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³CIRI/Rheumatology & Fraunhofer TMP, Goethe University, Frankfurt, Germany, ⁴Praxis fuer Innere Medizin, Aerztehaus Schoenwalde, Greifswald, Germany, ⁵Practice-based rheumatologist, Hildesheim, Germany, ⁶Practice-based rheumatologist, München, Germany, ⁷Rheumaklinik, Themistocles Gluck hospital - Rheumazentrum Ratingen, Ratingen, Germany
Background/Purpose: Psoriatic arthritis (PsA) divides into different subtypes, of which polyarthritis and spondylitis would be expected with the highest disease severity. We compared disease burden…
Abstract Number: 1296 • 2015 ACR/ARHP Annual Meeting
Evaluating Inter-Rater Reliability in Joint Count to Promote Quality and Trust in a Clinical Arthritis Care Team
Diane Tin¹, Lorna J. Bain¹, J Carter Thorne², Meen Jae Lee^2,3, Lois Derrick^1,4, E Jean Painter¹, Annabelle Estaban¹, Nooshin Samadi², Sue Charette¹, Sherry Hartnett¹, Carolyn Bornstein¹, Edward Ng² and Michael Aubrey², ¹The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ²Southlake Regional Health Centre, Newmarket, ON, Canada, ³Pharmacology, McGill University, Montreal, QC, Canada, ⁴The Arthritis Society, Toronto, ON, Canada
Background/Purpose: Joint count assessment is essential for the diagnosis and ongoing evaluation of Rheumatoid Arthritis (RA) disease activity. In our team based, interprofessional approach to…
Abstract Number: 1829 • 2015 ACR/ARHP Annual Meeting
Heart Rate Variability Is Associated with SLE Flare and with TNF- and IFN-Mediated Signaling
Aikaterini Thanou¹, Stavros Stavrakis², John Dyer², Stan Kamp³, Melissa E. Munroe¹, David Albert⁴, Judith A. James⁵ and Joan T. Merrill³, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Heart Rhythm Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴AliveCor, Inc., San Francisco, CA, ⁵Arthritis and Clinical Immunology, University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Decreased heart rate variability (HRV), associated with adverse outcomes in cardiovascular diseases, is frequently seen in patients with SLE. The LF/HF ratio, a HRV…
Abstract Number: 2492 • 2015 ACR/ARHP Annual Meeting
Implementation of the Clinical Disease Activity Index to Treat to Target Rheumatoid Arthritis in the Ambulatory Setting: A Plan Do Study Act Quality Analysis
Irene Lazarus¹, Salahuddin Kazi², Alok Dwivedi³, Christopher Dodoo⁴, Riya Joseph⁵, Mariela Hernandez⁶, Cam Duong⁷, Yasmin Sabet⁸ and Kanchan Pema⁹, ¹Internal Medicine, Texas Tech University Health Science Center, El Paso, TX, ²Internal Medicine/Rheumatology, UT Southwestern Medical Center, Dallas, TX, ³Biomedical Sciences Division of Biostatistics and Epidemiology, Texas Tech University Health Sciences Center, El Paso, TX, ⁴Texas Tech University Health Sciences Center, El Paso, TX, ⁵Internal Medicine, Methodist Dallas Medical Center, Dallas, TX, ⁶Paul Foster Medical School, Texas Tech University Health Sciences Center, El Paso, TX, ⁷Paul Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, ⁸Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, ⁹Internal Medicne/Rheumatology, Texas Tech University Health Science Center, El Paso, TX
Background/Purpose: Achieving tight control of RA with reliable methods to monitor and assess disease activity in a more objective way is imperative in clinical practice…
Abstract Number: 2645 • 2015 ACR/ARHP Annual Meeting
Changes in Clinical Disease Activity Index and Changes in Sleep Among RA Patients Initiating Disease Modifying Antirheumatic Drugs
Alyssa Wohlfahrt¹, ChihChin Liu², Yuanyu Lo¹, Clifton Bingham³, Marcy B. Bolster⁴, Tuhina Neogi⁵, Kristine Phillips⁶ and Yvonne C. Lee⁷, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Johns Hopkins University, Baltimore, MD, ⁴Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Clinical Epidemiology, BUSM, Boston, MA, ⁶Rheumatology, University of Michigan, Ann Arbor, MI, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Sleep problems affect over 60% of RA patients, but little is known about the relationship between sleep and inflammation in RA. Our primary objective…
Abstract Number: 2923 • 2015 ACR/ARHP Annual Meeting
The Effects of Disease Activity and Mood Disorders on Cognitive Function in Systemic Lupus Erythematosus
Michelle Barraclough^1,2, Rebecca Elliott^2,3, Shane McKie^2,3, Ben Parker^1,2 and Ian N. Bruce^1,2, ¹Stopford Building, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²Central Manchester University Hospital NHS Foundation Trust and Manchester Academic Health Science Centre, NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, ³Stopford Building, Neuroscience and Psychiatry Unit, Institute of Brain and Behaviour and Mental Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Cognitive dysfunction (CD) significantly affects SLE patients with many contributing causal factors. The effect of disease activity on cognitive function remains unclear and currently…
Abstract Number: 54 • 2015 ACR/ARHP Annual Meeting
Impact of Age at Disease Diagnosis on Clinical Manifestations, Disease Activity, and Outcomes in Patients with Systemic Lupus Erythematosus: Single-Center Prospective Cohort Study
Il Woong Sohn¹, Young Bin Joo¹, Soyoung Won², Seung Taek Song¹, Seung Lee³, Hye-Jin Jeong³ and Sang-Cheol Bae¹, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ³Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects frequently in their 20s and 30s. However, SLE could develop in other age group…
Abstract Number: 493 • 2015 ACR/ARHP Annual Meeting
Diagnostic Delay in Early Arthritis: Ten Years-Experience of a Single Center
Francesca Benaglio, Silvia Balduzzi, Serena Bugatti, Garifallia Sakellariou, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS S. Matteo Foundation, Pavia, Italy, Pavia, Italy
Background/Purpose: In the last 10 years a big effort has been made to reduce the diagnostic delay in patients with early arthritis, in order to…
Abstract Number: 688 • 2015 ACR/ARHP Annual Meeting
Clinical Improvements in Psoriasis and Psoriatic Arthritis with Surgical Weight Loss
Monica Sethi¹, Christine Ren-Fielding², Ana Clara Caminer^3,4, Jose U. Scher⁵ and Soumya M. Reddy⁶, ¹Department of Surgery, Division of Bariatric Surgery, New York University School of Medicine, New York, NY, ²Department of Surgery, New York University School of Medicine, New York, NY, ³Rheumatology, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Rosario, Argentina, ⁴Rheumatology, Sanatorio Parque, Rosario, Argentina, ⁵Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁶Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Obesity is more prevalent among patients with psoriasis and psoriatic arthritis (PsA). This correlation appears to be related to fat tissue-driven systemic inflammation. Although…
Abstract Number: 1318 • 2015 ACR/ARHP Annual Meeting
Prediction of Large Joint Destruction in Patients with Rheumatoid Arthritis Using FDG-PET/CT: A Prospective Study
Takahito Suto, Koichi Okamura, Yukio Yonemoto, Chisa Okura and Kenji Takagishi, Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
Background/Purpose: The assessments of joint damage in patients with rheumatoid arthritis (RA) are mainly restricted to small joints in the hands and feet. However, the…
Abstract Number: 1850 • 2015 ACR/ARHP Annual Meeting
Increased Levels of Immunoglobulin Binding Protein 1 Are Associated with Disease Activity Including Renal Damage in Patients with Systemic Lupus Erythematosus
Eun-Ju Lee^1,2, Seokchan Hong³, Doo-Ho Lim¹, Yong-Gil Kim¹, Chang-Keun Lee¹ and Bin Yoo¹, ¹Division of Rheumatology, Department of Internal Medicine, Department of Rheumatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, ²Asan Institute for Life Science, Asan Medical Center, Seoul, South Korea, ³Department of Rheumatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Background/Purpose: Systemic lupus erythematous (SLE) is a multisystem autoimmune inflammatory disease. Lupus nephritis (LN) is one of the most serious complications in patients with SLE.…
Abstract Number: 2493 • 2015 ACR/ARHP Annual Meeting
Improvement of Disease Activity and Quality of Care in a Cohort of Rheumatoid Arthritis Patients Treated with Conventional Dmard Therapy Under Treat to Target Recommendations and a Model of Patient-Centered Care
Pedro Ivan Santos-Moreno¹, Ginna Saavedra², Rosana Ramirez², Laura Villarreal², Ana Bolena Cardozo², Vanessa Giraldo², Paola Martinez², Adriana Sanchez², Merle Sanchez², Danny Gomez² and Juan Manuel Bello², ¹Rheumatology, Biomab, Center for Rheumatoid Arthritis., Bogota, Colombia, ²Rheumatology, Biomab, Center for Rheumatoid Arthritis, Bogota, Colombia, Bogota, Colombia
Background/Purpose: Treat to Target (T2T) strategy becomes from the need to develop therapeutic targets and tools to achieve defined outcomes in rheumatoid arthritis (RA). Moreover,…
Abstract Number: 2647 • 2015 ACR/ARHP Annual Meeting
Correlations Between Personality Types, Disease Activity and Quality of Life in As and RA Patients
Teodora Donisan¹, Madalina Dobrin², Denisa Predeteanu^3,4, Violeta Claudia Bojinca^4,5, Mihai Bojinca^6,7, Dinu Valentin Balanescu¹, Laura Grosanu^3,5, Florian Berghea^4,5, Cosmin Constantinescu^4,5, Daniela Opris^3,4, Andreea Borangiu^3,8, Ruxandra Ionescu^3,4 and Andra Rodica Balanescu^4,5, ¹University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, ²Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ³University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁴Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁵Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, ⁶Department of Internal Medicine and Rheumatology “Dr. I. Cantacuzino” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, ⁷Department of Internal Medicine and Rheumatology “Dr. I. Cantacuzino” Hospital, Bucharest, Romania, ⁸University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Romania, Bucharest, Romania
Background/Purpose: It is well established that health related quality of life (HRQoL) is low in patients (pts) with RA and AS. Type C and D…
Abstract Number: 2924 • 2015 ACR/ARHP Annual Meeting
Determinants of Damage in an SLE Cohort: Real World Data
Maria Francisca Moraes-Fontes¹, Eliana Silva², Nuno Riso³ and Margarida Jacinto⁴, ¹Autoimmune Diseases Unit, Serviço Medicina 7.2, Hospital de Curry Cabral, Centro Hospitalar Lisboa Central, Lisbon, Portugal, ²Patologia Clínica, Instituto Português de Oncologia, Francisco Gentil, Lisboa, Portugal, ³Serviço de Medicina 7.2, Hospital de Curry Cabral, Centro Hospitalar Lisboa Central, Lisbon, Portugal, ⁴Medicina Interna - Serviço 1, Hospital Espírito Santo - Évora, Évora, Portugal
Background/Purpose: Across the spectra of autoimmune diseases RA stands out, as biomarkers present from the onset are associated with severity and can be a guide…

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