Abstracts tagged "Disease Activity"

Abstract Number: 3016 • 2016 ACR/ARHP Annual Meeting
Validity of a 2-Component Disease Activity Score for Accurate Assessment of Synovitis in Rheumatoid Arthritis
Elizabeth M.A. Hensor^1,2, Paul McKeigue³, Philip G. Conaghan^1,2, Maya H. Buch^1,2, Jennifer H. Barrett^2,4, Jackie L. Nam^1,2, Marco Colombo⁵, Athina Spiliopoulou^5,6, Felix Agakov⁶, Stephen Kelly⁷, Myles J. Lewis⁷, Costantino Pitzalis⁷, Paul Emery^1,2, Ann W. Morgan^1,2 and IACON Consortium & PEAC Consortium, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ³Medical School, Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, ⁴School of Medicine, University of Leeds, Leeds, United Kingdom, ⁵Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, ⁶Pharmatics Limited, Edinburgh, Edinburgh, United Kingdom, ⁷Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom
Background/Purpose: The original Disease Activity Score (DAS) was derived from clinicians’ therapeutic decisions1, which may have been influenced by patient-subjective factors such as general health…
Abstract Number: 16 • 2016 ACR/ARHP Annual Meeting
Differences Between Patient and Physician Global Assessment on Rheumatoid Arthritis Disease Activity Status in High and Lower Income Countries Contribute to Inequity
SA Bergstra¹, R van den Berg¹, A Chopra², JAP da Silva³, D Vega-Morales⁴, N Govind⁵, TWJ Huizinga⁶ and RBM Landewé^7,8, ¹Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ²Department of Rheumatology, Center for Rheumatic Diseases, Pune, India, Pune, India, ³Department of Rheumatology, SRHUC, Coimbra, Portugal, Coimbra, Portugal, ⁴Universidad Autónoma de Nuevo Léon, Monterrey, Mexico, Monterrey, Mexico, ⁵Department of Rheumatology, University of the Witwatersrand, Johannesburg, South Africa, Johannesburg, South Africa, ⁶Leiden University Medical Centre, Leiden, Netherlands, ⁷Amsterdam Rheumatology & Immunology Center, Netherlands, Amsterdam, Netherlands, ⁸Zuyderland Medical Center, Heerlen, Netherlands, Heerlen, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) patients score their global disease activity (ptGD) on average higher than physicians (phGD). This difference can vary between countries with high…
Abstract Number: 510 • 2016 ACR/ARHP Annual Meeting
C-Reactive Protein and Disease Activity in Rheumatoid Arthritis: Impact of Obesity and Adiposity
Michael D. George¹, Jon T. Giles², Patricia P. Katz³, Said Ibrahim⁴, Grant W. Cannon⁵, Bryant R. England⁶, Liron Caplan⁷, Brian Sauer⁸, Kaleb Michaud⁹, Ted R Mikuls¹⁰ and Joshua F. Baker¹, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Rheumatology, Columbia University Medical Center, NY, NY, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴Medicine, University of Pennsylvania, Philadelphia, PA, ⁵Salt Lake City VA Medical Center and University of Utah Division of Rheumatology, Salt Lake City, UT, ⁶Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ⁷Denver Veterans Affairs Medical Center and UC Denver SOM, Denver, CO, ⁸IDEAS Center and Division of Epidemiology, HSR&D SLC VA Medical Center and University of Utah, Salt Lake City, UT, ⁹University of Nebraska Medical Center, Omaha, NE, ¹⁰Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: C-reactive protein (CRP) is used to assess disease activity in rheumatoid arthritis (RA), and previous work suggests that adiposity also impacts CRP levels. This…
Abstract Number: 722 • 2016 ACR/ARHP Annual Meeting
Impact of Aerobic Fitness on Axial Spondyloarthritis Activity: Systematic Review and Meta-Analysis of Controlled Studies
Frank Verhoeven¹, Xavier Guillot², Clément Prati³, Nicolas Tordi⁴, Céline Demougeot¹ and Daniel Wendling⁵, ¹EA 4267 FDE, FHU INCREASE, Université de Bourgogne Franche-Comté, Besançon, France, ²EA 4267 FDE, FHU INCREASE, Université de Bourgogne FrancheComté, Besançon, France, ³FDE EA4267, FHU INCREASE, Bourgogne Franche-Comté University, Besançon, France, ⁴EA 4267 FDE, FHU INCREASE,, Bourgogne Franche-Comté University, Besançon, France, ⁵Service de Rhumatologie, CHU Jean Minjoz, Besancon, France
Background/Purpose: The current ASAS recommendations for the management of the ankylosing spondylitis suggest, beside pharmacological therapy, a significant part of physical therapy with supervised exercises.…
Abstract Number: 1158 • 2016 ACR/ARHP Annual Meeting
Effects of an Educational Program Using Treat to Target Strategy in Korean Patients with Rheumatoid Arthritis
SeungIn Paek¹, Seo Hwa Kim², Haneul Kim³, Min Kyung Chung⁴, Jennifer Lee⁵, Seung-Ki Kwok⁶, Ji Hyeon Ju⁷, Sung-Hwan Park⁷ and Kyeong Yae Sohng⁸, ¹Center for Rheumatic Diseases, Seoul ST Mary's Hospital, The Catholic University of Korea, Seoul, South Korea, ²Division of Rheumatology,, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, ³Division of Rheumatology,, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary’s Hospital, Seoul, Republic of Korea, Seoul, Korea, The Republic of, ⁴Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, ⁵Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁶[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁸College of Nursing, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: The purpose of this study was to investigate the effects of an educational program using T2T (Treat RA to Target, T2T) strategy on Korean…
Abstract Number: 1470 • 2016 ACR/ARHP Annual Meeting
Moderate to Severe Disease Activity in Rheumatoid Arthritis Is Associated with Myocardial 18f-Fluorodeoxyglucose (18F-FDG) Uptake
Isabelle Amigues¹, Jon T. Giles², Afshin Zartoshti³, Rachelle Morgenstern⁴, Raul Flores⁵, Sabahat Bokhari⁶ and Joan Bathon⁷, ¹Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Rheumatology, Columbia University Medical Center, NY, NY, ³Rheumatology, Columbia University, College of Physicians & Surgeons, New York city, NY, ⁴Cardiology, columbia university college of physicians and surgeons, New York city, NY, ⁵Medicine, Columbia University, New York Presbyterian, New York city, NY, ⁶Cardiology, Columbia University College of Physicians & Surgeons, NY, NY, ⁷Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: RA patients are at increased risk for developing heart failure (HF) even after controlling for coronary artery disease (CAD), indicating that factors other than…
Abstract Number: 1700 • 2016 ACR/ARHP Annual Meeting
Treating Psoriatic Arthritis (PsA) to Target: Defining Psoriatic Arthritis Disease Activity Score (PASDAS) That Reflects Disease Activity in Psa
Matthew Got¹, Suzanne Li², Anthony V. Perruccio^3,4, Dafna D Gladman¹ and Vinod Chandran⁵, ¹University of Toronto, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, ⁴Arthritis Program, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, ⁵Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: PASDAS is a composite disease activity measure (range 0–10) for psoriatic arthritis (PsA). Recently, PASDAS disease activity cutoffs were proposed and a minimal disease…
Abstract Number: 2044 • 2016 ACR/ARHP Annual Meeting
Effect of Pregnancy on Disease Flares in Patients with Systemic Lupus Erythematosus
Amanda M. Eudy^1,2, Anna Maria Siega-Riz², Stephanie Engel², Nora Franceschini², Annie Green Howard³, Megan E. B. Clowse¹ and Michelle Petri⁴, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: There are conflicting results about the effect pregnancy has on the health of systemic lupus erythematosus (SLE) women. The objective of the current analysis…
Abstract Number: 2508 • 2016 ACR/ARHP Annual Meeting
Significant Improvement of Rheumatoid Arthritis (RA) Outcome with Repeat Application of Disease Management (SSDM) Mobiles Tools: A Cohort Study of RA Patients in China
Jing Yang¹, Hongzhi Wang², Wenqiang Fan³, Hua Wei⁴, Xinwang Duan⁵, Rong Mu⁶, Yu Zhang¹, Xiafei Xin⁷, Jinmei Zou¹, Xiaofeng Li⁸, Jie Wu⁹, Xiaomei Li¹⁰, Guosheng Wang¹¹, Hong Liu¹, Fei Xiao¹², Hui Xiao¹², Yuhua Jia¹², Yuan Liu¹², Bing Wu¹² and Xiaofeng Zeng¹³, ¹Department of rheumatology, Central Hospital of MianYang, Sichuan, Mian Yang, China, ²The First Hospital of Jiaxing, Jiaxing, China, ³Department of rheumatology, Central Hospital of XinXiang, Henan, XinXiang, China, ⁴No 98,Nantong West Rd,Yangzhou, Northern Jiangsu People's Hospital, Yangzhou, China, ⁵Department of rheumatology, The Second Affiliated Hospital of Nanchang University, Nanchang, China, ⁶Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China, ⁷Ningbo First Hospital, Zhejiang, Ningbo, China, ⁸The Second Affiliated Hospital of Shanxi Medical College, Taiyuan, China, ⁹Central Hospital of XinXiang, Henan, XinXiang, China, ¹⁰Department of Rheumatology and Immunology, Anhui Medical University Affiliated Provincial Hospital, China, Hefei, Anhui, China, ¹¹Department of rheumatology, Anhui Medical University Affiliated Provincial Hospital, Hefei, China, ¹²Gothic Internet Technology Corporation, Shanghai, China, ¹³Department of Rheumatology and Immunology, Peking Union Medical College Hospital, Beijing, China
Background/Purpose: There are more than 5 million rheumatoid arthritis (RA) patients in China, but only 5,000 rheumatologists. Treat-to-Target (T2T) strategy are critical for the treatment…
Abstract Number: 2769 • 2016 ACR/ARHP Annual Meeting
Does Gender Make a Difference in “Composite Psoriatic Disease Activity Index (CPDAI)” in Patients with Psoriatic Arthritis?
Gokce Kenar¹, Handan Yarkan², Berrin Zengin¹, Gerçek Can², Merih Birlik¹, Nurullah Akkoc¹ and Fatos Onen¹, ¹Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ²Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey
Background/Purpose: “Composite psoriatic disease activity index (CPDAI)” includes 5 domains: peripheral joints, skin, enthesitis, dactylitis, and spinal manifestations in psoriatic arthritis (PsA) which is a…
Abstract Number: 3031 • 2016 ACR/ARHP Annual Meeting
Rethinking Primary Sjögren’s Syndrome: Stratification By Clinical Phenotypes to Improve Understanding of Disease Pathogenesis, Trial Design, Clinical Management and Prospective Health Gains?
Dennis Lendrem¹, Nadia Howard Tripp^2,3, Xavier Mariette⁴, Svein Joar A. Johnsen⁵, Jessica Tarn⁶, Katie Hackett⁶, Bridget Griffiths⁷, Sheryl Mitchell⁸, Alain Saraux⁹, Valerie Devauchelle¹⁰, Katrine Norheim¹¹, John D. Isaacs¹², Peter McMeekin^13,14, Simon Bowman¹⁵, Roald Omdal¹⁶, Jacques-Eric Gottenberg¹⁷ and Wan-Fai Ng¹⁸, ¹Newcastle upon Tyne, Newcastle University, Newcastle upon Tyne, United Kingdom, ²Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom, ³Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom, ⁴Université Paris-Sud, AP-HP, Hôpitaux Universitaires Paris-Sud, Paris, France, ⁵Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, ⁶Newcastle University, Newcastle-upon-Tyne, United Kingdom, ⁷Rheumatology, Freeman Hospital, Newcastle Upon Tyne, United Kingdom, ⁸Freeman Hospital, Newcastle upon Tyne, United Kingdom, ⁹Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, ¹⁰Service de Rhumatologie, Department of Rheumatology, Brest University Hospital, Brest, France, Brest, France, ¹¹Stavanger University Hospital, Stavanger, Norway, ¹²Newcastle University and the Freeman Hospital, Newcastle-upon-Tyne, United Kingdom, ¹³Institute of Health and Society, Newcastle University, Newcastle-upon-Tyne, United Kingdom, ¹⁴Northumbria University, Newcastle-upon-Tyne, United Kingdom, ¹⁵Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, ¹⁶University of Bergen, Bergen, Norway, ¹⁷Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, ¹⁸Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
Background/Purpose: Primary SjšgrenÕs Syndrome (pSS) is a chronic autoimmune rheumatic disease causing a wide-range of symptoms including dryness, pain and fatigue. Individual patient experiences of…
Abstract Number: 25 • 2016 ACR/ARHP Annual Meeting
Have Outcomes of Patients with Inflammatory Arthritis Improved in the New Millennium? a Comparison of the 10 Year Outcome in Cohorts Recruited in 1990-4 and 2000-4
James Gwinnutt¹, Deborah P.M. Symmons^1,2, Alex J Macgregor^3,4, Jacqueline Chipping^3,4, Tarnya Marshall^3,4, Mark Lunt¹ and Suzanne M.M. Verstappen¹, ¹Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom, ³Rheumatology, Norfolk and Norwich University Hospital, Norwich, United Kingdom, ⁴School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, United Kingdom
Background/Purpose: New treatments have improved the short term outlook for patients with inflammatory polyarthritis (IP) over the past 20 years. However there is limited evidence…
Abstract Number: 511 • 2016 ACR/ARHP Annual Meeting
Complement C3 and C4 Levels and Its Correlation with Disease Activity in Rheumatoid Arthritis Patients
Julia Sosa¹, Silvia Beatriz Papasidero², María Alejandra Medina¹, Diana Klajn³, Rafael Chaparro del Moral², José Angel Caracciolo⁴, Luciana Casalla⁵, Lucía Zárate⁵, Nieves Capozzi⁵, Josefina Marcos⁶, Mercedes Argentina García⁶, Ana Quinteros⁷, Maria Olga Leal⁷, Dora Lia Vásquez⁷, María Inés Stancich⁸, Analia Alvarez⁹, Carolina Sanchez Andía⁹, Karin Kirmayr¹⁰, María de los Ángeles Correa¹¹ and A. Constantino¹², ¹Rheumatology Department, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, ²Rheumatology Department, Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, ³Research Committee, Research Committee, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, ⁴Rhematology Department, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, ⁵Rheumatology Section, Hospital Posadas, Buenos Aires, Argentina, ⁶Rheumatology Unit, HIGA San Martín La Plata, La Plata, Argentina, ⁷Centro Integral De Reumatologia, Tucumán, Argentina, ⁸Rheumatology Department, Hospital Nacional De Clínicas, Córdoba, Argentina, ⁹Rheumatology Department, Hospital Penna, Buenos Aires, Argentina, ¹⁰Rheumatology Department, Sanatorio San Carlos, Buenos Aires, Argentina, ¹¹Rheumatology Department, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ¹²Hospital Nacional De Clínicas, Córdoba, Argentina
COMPLEMENT C3 AND C4 LEVELS AND ITS CORRELATION WITH DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS PATIENTS Background/Purpose: Cytokines play a major role in the pathogenesis…
Abstract Number: 754 • 2016 ACR/ARHP Annual Meeting
The Duration of Anti-Malarial Agent Intake in the First 5 Years of the Disease and Prognosis in Patients with Systemic Lupus Erythematosus
Rattapol Pakchotanon¹, Dafna D. Gladman², Jiandong Su² and Murray Urowitz³, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ³Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: Anti-malarial agents (AM) prevent damage in patients with systemic lupus erythematosus (SLE). We aimed to examine whether the duration of AM therapy early in…
Abstract Number: 1214 • 2016 ACR/ARHP Annual Meeting
Autoantibody Reactivities Correlated with SLE Disease Activity Identified By the SLE-key® iCHIP® Platform
Chaim Putterman¹, Pennina Safer², Keren Jakobi², Rachel Sorek², Ilana Gilkaite², Kyle Ferber³, Steve Wallace³, Amanda Harris Altice³, D. Scott Batty³ and Irun R Cohen^2,4, ¹Albert Einstein College of Medicine, Bronx, NY, ²ImmunArray LTD, Rehovot, Israel, ³ImmunArray Inc., Richmond, VA, ⁴Immunology, Weizmann Institute of Science, Rehovot, Israel
Background/Purpose: We have developed an antigen microarray technology to study antibody profiles to elucidate and diagnose clinical states of SLE patients – the iCHIP® SLE-key®…

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