Abstracts tagged "Disease Activity"

Abstract Number: 678 • 2015 ACR/ARHP Annual Meeting
Clinical Characteristics and Disease Activity in Psoriatic Arthritis Patients with Dactylitis or Enthesitis: Results from Corrona Registry
Philip J. Mease¹, Chitra Karki², Carol J. Etzel^2,3, Arthur Kavanaugh⁴, Christopher T. Ritchlin⁵, Wendi Malley², Vivian Herrera⁶, Jacqueline B. Palmer⁶ and Jeffrey D. Greenberg^2,7, ¹Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, ²Corrona, LLC, Southborough, MA, ³The University of Texas MD Anderson Cancer Center, Houston, TX, ⁴University of California San Diego, La Jolla, CA, ⁵Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY, ⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁷New York University School of Medicine, Millburn, NJ
Background/Purpose: Psoriatic arthritis (PsA) exhibits considerable heterogeneity in its presentation and course, which contributes to the complexity of diagnosis and assessment. Enthesitis, inflammation at the…
Abstract Number: 1241 • 2015 ACR/ARHP Annual Meeting
Identification and Validation of Diagnostic and Activity Urinary Metabolomic Biomarkers in Immune-Mediated Inflammatory Diseases
Arnald Alonso¹, Jesús Tornero², Antonio Fernandez-Nebro³, Juan D. Cañete⁴, Eugeni Domènech⁵, Javier P. Gisbert⁶, Carlos Ferrándiz⁵, Eduardo Fonseca⁷, Valle García⁸, Francisco Blanco⁷, Jesus Rodriguez⁹, Jordi Gratacós¹⁰, Patricia E. Carreira¹¹, Antonio Julià¹, Raül Tortosa¹, Maria López-Lasanta¹², Xavier Correig¹³ and Sara Marsal¹, ¹Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ²Rheumatology Department, Hospital Universitario Guadalajara, Guadalajara, Spain, ³Rheumatology, Hospital Universitario Carlos Haya, Malaga, Spain, ⁴Unitat d’Artritis, Servei de Reumatologia, Hospital Clínic de Barcelona and Institut d’Investigacions Biomèdiques August Pí i Sunyer, Barcelona, Spain, ⁵Hospital Universitari Germans Trias I Pujol, Badalona, Spain, ⁶Hospital Universitario de la Princesa, Madrid, Spain, ⁷Complejo Hospitalario Juan Canalejo, A Coruña, Spain, ⁸Hospital Universitario Reina Sofía, Córdoba, Spain, ⁹Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, ¹⁰Hospital Parc Taulí, Sabadell, Spain, ¹¹Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, ¹²Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ¹³CIBERDEM, Metabolomics Platform, Reus, Spain
Background/Purpose: The recent advances in metabolomics have allowed the study of the regulatory processes linked to metabolism. The comprehensive analysis of the metabolome in biological samples…
Abstract Number: 1826 • 2015 ACR/ARHP Annual Meeting
Small LDL-P Increases with Increased Disease Activity in SLE
Laura Durcan¹, Deborah Winegar², Margery Connelly², James Otvos², Laurence S Magder³ and Michelle Petri¹, ¹Rheumatology, Johns Hopkins University Hospital, Baltimore, MD, ²LabCorp, Raleigh, NC, ³Epidemiology and Preventive Medicine, University of MD, Baltimore, MD
Background/Purpose: Systemic lupus erythematosus (SLE) associates with accelerated atherosclerotic cardiovascular (CV) disease which is not fully explained by traditional CV risk factors. Disease activity, prednisone…
Abstract Number: 2491 • 2015 ACR/ARHP Annual Meeting
Documentation of Disease Activity Score As Part of a Treat to Target Strategy in Rheumatoid Arthritis
Sarah Homann¹ and Beth Scholz², ¹Rheumatology, University of Texas Health Sciences Center at Houston, Houston, TX, ²University of Texas Health Sciences Center at Houston, Houston, TX
Background/Purpose: Compared to routine care, the Treat to Target (TTT) strategy for rheumatoid arthritis (RA) has been validated to improve functional and radiographic outcomes via…
Abstract Number: 2644 • 2015 ACR/ARHP Annual Meeting
The Relationship Between Disease Activity and Cognitive Impairment in Patients with Rheumatoid Arthritis
Sang-Il Lee¹, Young Sun Suh¹, Yun-Hong Cheon¹, Hyun-Ok Kim¹, Hyun-Su Yang², Ki-Soo Park², Eun-Kyoung Park³, Seung-Geun Lee⁴, Chang-Nam Son⁵, Ji-Min Kim⁵ and Sang-Hyon Kim⁶, ¹Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ²Department of Preventive Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Busan National University School of Medicine, Busan, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea
Background/Purpose: Only few studies investigated the prevalence and risk factors of cognitive impairment in patients with rheumatoid arthritis (RA), however, results are controversial. Therefore we…
Abstract Number: 2914 • 2015 ACR/ARHP Annual Meeting
Modifiable and Non-Modifiable Correlates of Satisfaction with Care in Systemic Lupus Erythematosus
Syed Alam¹, Nisarg Gandhi², Alana Nevares¹, Ailda Nika², Winston Sequeira² and Meenakshi Jolly³, ¹Internal Medicine, Cook County Hospital, Chicago, IL, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³Department of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Systemic Lupus Erythematosus (SLE) a chronic disease, predominantly of young women, which may involve various organs, and is marked by periods of disease flares,…
Abstract Number: 38 • 2015 ACR/ARHP Annual Meeting
Impact of Obesity on the Disease Course of Rheumatoid Arthritis
Yang (Linda) Liu¹, Gilaad Kaplan², Bertus Eksteen³ and Cheryl Barnabe¹, ¹Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ²Division of Gastroenterology, University of Calgary, Calgary, AB, Canada, ³Division of Hepatology, University of Calgary, Calgary, AB, Canada
Background/Purpose: Obesity results in a higher risk for the development of rheumatoid arthritis (RA) but is associated with less radiographic damage. The evidence for the…
Abstract Number: 478 • 2015 ACR/ARHP Annual Meeting
Impact of Comorbidities on the Multi-Biomarker Disease Activity Test in Rheumatoid Arthritis Patients
Jeffrey R. Curtis¹, Jeffrey D. Greenberg², Leslie Harrold³ and J. Lynn Palmer⁴, ¹University of Alabama at Birmingham, Birmingham, AL, ²Corrona, LLC, Southborough, MA, ³Department of Medicine, UMass Memorial Medical Center, Worcester, MA, ⁴Corrona Research Foundation, Albany, NY
Background/Purpose: The multi-biomarker disease activity (MBDA) score [Vectra] has been evaluated in a number of settings, yet has only limited data evaluating whether it is…
Abstract Number: 679 • 2015 ACR/ARHP Annual Meeting
Patients with Psoriatic Arthritis and Oligoarthritic Subtype Report Higher Disease Burden Than Patients with a Polyarthritic Pattern – Data from the German Collaborative Arthritis Centres
Dörte Huscher¹, Katinka Albrecht², Sascha Bischoff², Katja Thiele², Frank Behrens³, Kathrin Fischer⁴, Ulrich von Hinüber⁵, Susanna Späthling-Mestekemper⁶, Siegfried Wassenberg⁷ and Angela Zink¹, ¹German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³CIRI/Rheumatology & Fraunhofer TMP, Goethe University, Frankfurt, Germany, ⁴Praxis fuer Innere Medizin, Aerztehaus Schoenwalde, Greifswald, Germany, ⁵Practice-based rheumatologist, Hildesheim, Germany, ⁶Practice-based rheumatologist, München, Germany, ⁷Rheumaklinik, Themistocles Gluck hospital - Rheumazentrum Ratingen, Ratingen, Germany
Background/Purpose: Psoriatic arthritis (PsA) divides into different subtypes, of which polyarthritis and spondylitis would be expected with the highest disease severity. We compared disease burden…
Abstract Number: 1296 • 2015 ACR/ARHP Annual Meeting
Evaluating Inter-Rater Reliability in Joint Count to Promote Quality and Trust in a Clinical Arthritis Care Team
Diane Tin¹, Lorna J. Bain¹, J Carter Thorne², Meen Jae Lee^2,3, Lois Derrick^1,4, E Jean Painter¹, Annabelle Estaban¹, Nooshin Samadi², Sue Charette¹, Sherry Hartnett¹, Carolyn Bornstein¹, Edward Ng² and Michael Aubrey², ¹The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ²Southlake Regional Health Centre, Newmarket, ON, Canada, ³Pharmacology, McGill University, Montreal, QC, Canada, ⁴The Arthritis Society, Toronto, ON, Canada
Background/Purpose: Joint count assessment is essential for the diagnosis and ongoing evaluation of Rheumatoid Arthritis (RA) disease activity. In our team based, interprofessional approach to…
Abstract Number: 1829 • 2015 ACR/ARHP Annual Meeting
Heart Rate Variability Is Associated with SLE Flare and with TNF- and IFN-Mediated Signaling
Aikaterini Thanou¹, Stavros Stavrakis², John Dyer², Stan Kamp³, Melissa E. Munroe¹, David Albert⁴, Judith A. James⁵ and Joan T. Merrill³, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Heart Rhythm Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ³Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴AliveCor, Inc., San Francisco, CA, ⁵Arthritis and Clinical Immunology, University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Decreased heart rate variability (HRV), associated with adverse outcomes in cardiovascular diseases, is frequently seen in patients with SLE. The LF/HF ratio, a HRV…
Abstract Number: 2492 • 2015 ACR/ARHP Annual Meeting
Implementation of the Clinical Disease Activity Index to Treat to Target Rheumatoid Arthritis in the Ambulatory Setting: A Plan Do Study Act Quality Analysis
Irene Lazarus¹, Salahuddin Kazi², Alok Dwivedi³, Christopher Dodoo⁴, Riya Joseph⁵, Mariela Hernandez⁶, Cam Duong⁷, Yasmin Sabet⁸ and Kanchan Pema⁹, ¹Internal Medicine, Texas Tech University Health Science Center, El Paso, TX, ²Internal Medicine/Rheumatology, UT Southwestern Medical Center, Dallas, TX, ³Biomedical Sciences Division of Biostatistics and Epidemiology, Texas Tech University Health Sciences Center, El Paso, TX, ⁴Texas Tech University Health Sciences Center, El Paso, TX, ⁵Internal Medicine, Methodist Dallas Medical Center, Dallas, TX, ⁶Paul Foster Medical School, Texas Tech University Health Sciences Center, El Paso, TX, ⁷Paul Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, ⁸Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, ⁹Internal Medicne/Rheumatology, Texas Tech University Health Science Center, El Paso, TX
Background/Purpose: Achieving tight control of RA with reliable methods to monitor and assess disease activity in a more objective way is imperative in clinical practice…
Abstract Number: 2645 • 2015 ACR/ARHP Annual Meeting
Changes in Clinical Disease Activity Index and Changes in Sleep Among RA Patients Initiating Disease Modifying Antirheumatic Drugs
Alyssa Wohlfahrt¹, ChihChin Liu², Yuanyu Lo¹, Clifton Bingham³, Marcy B. Bolster⁴, Tuhina Neogi⁵, Kristine Phillips⁶ and Yvonne C. Lee⁷, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Johns Hopkins University, Baltimore, MD, ⁴Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Clinical Epidemiology, BUSM, Boston, MA, ⁶Rheumatology, University of Michigan, Ann Arbor, MI, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Sleep problems affect over 60% of RA patients, but little is known about the relationship between sleep and inflammation in RA. Our primary objective…
Abstract Number: 2923 • 2015 ACR/ARHP Annual Meeting
The Effects of Disease Activity and Mood Disorders on Cognitive Function in Systemic Lupus Erythematosus
Michelle Barraclough^1,2, Rebecca Elliott^2,3, Shane McKie^2,3, Ben Parker^1,2 and Ian N. Bruce^1,2, ¹Stopford Building, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²Central Manchester University Hospital NHS Foundation Trust and Manchester Academic Health Science Centre, NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, ³Stopford Building, Neuroscience and Psychiatry Unit, Institute of Brain and Behaviour and Mental Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Cognitive dysfunction (CD) significantly affects SLE patients with many contributing causal factors. The effect of disease activity on cognitive function remains unclear and currently…
Abstract Number: 54 • 2015 ACR/ARHP Annual Meeting
Impact of Age at Disease Diagnosis on Clinical Manifestations, Disease Activity, and Outcomes in Patients with Systemic Lupus Erythematosus: Single-Center Prospective Cohort Study
Il Woong Sohn¹, Young Bin Joo¹, Soyoung Won², Seung Taek Song¹, Seung Lee³, Hye-Jin Jeong³ and Sang-Cheol Bae¹, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ³Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects frequently in their 20s and 30s. However, SLE could develop in other age group…

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