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Abstracts tagged "Disease Activity"

  • Abstract Number: 512 • 2015 ACR/ARHP Annual Meeting

    Physical Function and Inflammatory Activity in Rheumatoid Arthritis Patients. Is Disease Duration Important?

    Emmanuel Bertiller1, Facundo Vergara1, Maria de los Angeles Gallardo1, Javier Rosa2, Erika Catay3, Marina Scolnik1, Maria Victoria Garcia4, Mirtha Sabelli5 and Enrique R. Soriano6, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Rheumatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 3Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio,, Buenos Aires, Argentina, 4Internal Services, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 5Cabrera 2964 Piso 6, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 6Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: HAQ (Health Assessment Questionnaire) assesses functional disability in rheumatoid arthritis (RA) patients. Correlation between HAQ and disease activity might change according to the length…
  • Abstract Number: 731 • 2015 ACR/ARHP Annual Meeting

    Damage and Mortality in SLE: Cluster Analysis of Patients from SLE Registry from the Spanish Society for Rheumatology (RELESSER)

    JM Pego-Reigosa1,2, Ana Lois-Iglesias3,4, Francisco Javier Lopez Longo5, María Galindo6, J Calvo-Alen7, Jacobo de Uña8, Vanessa Balboa9, Alejandro Olivé10, Coral Mouriño-Rodríguez1, Maria Teresa Oton Sanchez11, Jesus Ibañez12, Maria Loreto Horcada13, Ana Sánchez Atrio14, Carlos Alberto Montilla Morales15, Rafael-Benito Melero González1, Ricardo Blanco16, Elvira Diez Alvarez17, Monica Fernandez Castro18, Esther Ruiz Lucea19, José Hernández Beiraín20, Marian Gantes21, Blanca Hernández-Cruz22, Angela Pecondon-Español23, Nuria Lozano-Rivas24, Gema Bonilla25, Vicente Torrente-Segarra26, Iñigo Rúa-Figueroa27 and RELESSER EASSER Group, 1Rheumatology, EOXI Vigo, Vigo, Spain, 2Rheumatology, Instituto de Investigación Biomédica de Vigo(IBIV), Vigo, Spain, 3Rheumatology, Hospital Ntra Señora de La Esperanza, Santiago de Compostela, Spain, 4Rheumatology, University A Coruña, A Coruña, Spain, 5Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 6Servicio de Reumatología, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain, 7Rheumatology, Hospital de Sierrallana, Torrelavega, Spain, 8Statistics and OR, Vigo University, Vigo, Spain, 9Statistics and OR, Viho University, Vigo, Spain, 10Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 11Rheumatology, Hospital of Torrejón, Madrid, Spain, 12Rheumatology, Hospital Povisa, Vigo, Spain, 13Rheumatology, Complejo Hospitalario de Navarra, Pamplona, Spain, 14University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, 15Rheumatology, Hospital Universitario de Salamanca, Salamanca, Spain, 16Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 17Rheumatology, Hospital de León, León, Spain, 18Rheumatology, Hospital Puerta de Hierro, Madrid, Spain, 19Rheumatology, Hospital de Basurto, Bilbao, Spain, 20Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, 21Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, 22Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, 23Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, 24Rheumatology, Hospital Virgen de la Arrixaca, Murcia, Spain, 25Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 26Hospital General Hospitalet-Sant Joan Despí Moisès Broggi, Hospitalet Llobregat, Barcelona, Spain, 27Rheumatology, Hospital Universitario Dr Negrín. Las Palmas, Las Palmas de Gran Canaria, Spain

    Background/Purpose: Damage in SLE is associated with mortality. Not every damage manifestation is associated in the same way. Some studies were made assessing this relation…
  • Abstract Number: 1505 • 2015 ACR/ARHP Annual Meeting

    Carotid Artery Atherosclerosis in Patients with Active Rheumatoid Arthritis: Predictors of Plaque Occurrence and Progression over 24 Weeks

    Tatiana Nevskaya1, Janet E. Pope2, Lillian Barra3 and Grace Parraga4, 1Medicine, Division of Rheumatology, University of Western Ontario, London, ON, Canada, 2University of Western Ontario, London, ON, Canada, 3Medicine, Division of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, 4University of Western Ontario, Robarts Research Institute, London, ON, Canada

    Background/Purpose: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). Methods: Carotid arteries of RA patients were scanned…
  • Abstract Number: 1987 • 2015 ACR/ARHP Annual Meeting

    Dramatic Efficacy of Tocilizumab As First Line Therapy in Patients with Recent Polymyalgia Rheumatica (PMR): Results of the First Longitudinal Prospective Study

    Valerie Devauchelle1, Alain Saraux2, Jean-Marie Berthelot3, Divi Cornec4, Yves Renaudineau5, Sandrine Jousse-Joulin1, Thierry Marhadour6, Solene Querellou7, Florent Garrigues8, Michel De Bandt9 and Maelenn Gouillou10, 1Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, 2Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, 3Rheumatology, University Hospital, Nantes, France, 4Department of rheumatology, Brest Occidentale University, Brest, France, 5Immunology, Brest University Medical School Hospital, Brest, France, 6CHU La Cavale Blanche, Brest, France, 7Nuclear Medicine Department, Morvan University Hospital, Brest, France, 8Radiology department, Cavale Blanche Hospital and Brest Occidentale University, Brest, France, 9Rheumatology department, CHU Fort de France, Fort de France, France, 10Clinical Investigation Centre (CIC) 1412, CHU Cavale Blanche- Institut National de la Santé et de la Recherche Médicale (INSERM), Brest, France

    Background/Purpose: Glucocorticoids (GCs) are the cornerstone treatment of polymyalgia rheumatica (PMR) but induce several adverse events. Methods: Objectives: To evaluate efficacy and safety of tocilizumab…
  • Abstract Number: 2519 • 2015 ACR/ARHP Annual Meeting

    Pregnancy in Psoriatic Arthritis: A Case Series

    Maria Mouyis1, Clare Thornton1, David Williams2,3 and Ian Giles4, 1Rheumatology, University College London Hospital, London, United Kingdom, 2Institute for Women’s Health, University College London, London, United Kingdom, 3University College London, London, United Kingdom, 4Rayne Institute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom

    Background/Purpose: It is recognised that active disease in women with inflammatory arthritis is associated with adverse pregnancy outcomes. Most studies however, have focussed upon patients…
  • Abstract Number: 2657 • 2015 ACR/ARHP Annual Meeting

    Influence of Anxiety and Depression on the Swollen to Tender Joint Count Ratio: In Pursuit of a Phenotype of RA Patients with Somatic Complaints in a U.S. Veteran Population

    Iris Navarro-Millan1, Archana Jain1, Rebecca Belsom1, Angelo L. Gaffo2, Shuo Yang3, Ted R. Mikuls4 and Jeffrey R. Curtis5, 1Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2Rheumatology, Birmingham VA Medical Center, Birmingham, AL, 3Clinical Immunology/Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4Medicine, University of Nebraska Medical Center, Omaha, NE, 5Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: The utilization of a swollen (SJC) to tender joint count (TJC) ratio (STR = (SJC/TJC)) has been proposed in the past to identify a…
  • Abstract Number: 2992 • 2015 ACR/ARHP Annual Meeting

    Identification of a New Set of Activity Criteria for Systemic Sclerosis. Preliminary Report

    Gabriele Valentini1, Michele Iudici2, Veronika K. Jaeger3, Christopher P. Denton4, Oliver Distler5, Otylia M. Kowal-Bielecka6, Ulf Müller-Ladner7, Gabriela Riemekasten8, Ulrich A. Walker3, Suzana Jordan5, Elise Siegert8, Serena Vettori2 and Yannick Allanore9, 1Department of Clinical and Experimental Medicine, Rheumatology Unit, Rheumatology Unit, Second University of Naples, Naples, Italy, 2Department of Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, 3Department of Rheumatology, University Hospital Basel, Basel, Switzerland, 4Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom, 5Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 6Department of Rheumatology and Internal Medicine, Medical University in Bialystok, Bialystok, Poland, 7Internal Medicine and Rheumatology, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, 8Rheumatology and Clinical Immunology, Charité – University Hospital, Berlin, Berlin, Germany, 9Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France

    Background/Purpose: The European Scleroderma Study Group (EScSG) Activity Index developed in 2001 has some limitations due to the procedure underlying its development and the inclusion…
  • Abstract Number: 158 • 2015 ACR/ARHP Annual Meeting

    Ultrasound Score of Dominant Hand in Patients with Rheumatoid Arthritis Correlates with DAS28CRP, CDAI and SDAI but Not RAPID-3

    Allen P. Anandarajah1, Bethany Marston2, Linda Grinnell-Merrick2 and Ralf G. Thiele3, 1Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, 2Rheumatology, University of Rochester Medical Center, Rochester, NY, 3University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Musculoskeletal ultrasound (MUS) allows for direct visualization of diverse pathologic features such as cortical bone erosions, synovial thickening, and synovial vascularity in the joints…
  • Abstract Number: 515 • 2015 ACR/ARHP Annual Meeting

    Are Changes in Autoantibody Levels Reflecting Change in Prognosis of Rheumatoid Arthritis?

    Manuel Unger1, Farideh Alasti1, Paul Studenic1, Josef S. Smolen2,3 and Daniel Aletaha1, 1Department of Internal Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 22nd Department of Medicine, Hietzing Hospital, Vienna, Austria, 3Department of Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria

    Background/Purpose: The presence of rheumatoid factor (RF) and antibodies against citrullinated peptides (ACPA) is associated with progression of joint damage in patients with rheumatoid arthritis…
  • Abstract Number: 734 • 2015 ACR/ARHP Annual Meeting

    Disease Patterns, Flare Incidence and Organ Damage Among Filipino Patients with Systemic Lupus Erythematosus: a One-Year Observational Study

    Mary Flor Joy Edar, Leonid Zamora, Catherine Macapagal and Sandra V. Navarra, Rheumatology, University of Santo Tomas Hospital, Manila, Philippines

    Background/Purpose: This study describes the disease patterns, flare incidence, hospitalizations and causes of mortality in a cohort of Filipino patients with systemic lupus erythematosus (SLE),…
  • Abstract Number: 1544 • 2015 ACR/ARHP Annual Meeting

    Resiliency As a Predictor of Depressive Symptoms in Patients with Rheumatoid Arthritis

    Matt Woo1, Nadil Zeiadin1, Hayley Yurgan2, Dean Tripp3 and Mala Joneja1, 1Medicine, Queen's University, Kingston, ON, Canada, 2Psychology, Queen's University, Kingston, ON, Canada, 3Psychology, Anaesthesiology, Urology, Queen's University, Kingston, ON, Canada

    Background/Purpose: Rheumatoid arthritis is a chronic, systemic, autoimmune disease affecting 0.5 – 1% of the adult population that leads to a progressive decline in functional…
  • Abstract Number: 2066 • 2015 ACR/ARHP Annual Meeting

    Elevated Innate, Adaptive, and TNF-Superfamily Soluble Inflammatory Mediators Mark Impending Disease Flare, While Regulatory Mediators Distinguish Lack of Impending Disease Flare in African-American SLE Patients with Active Disease

    Melissa E. Munroe1, Evan G. Vista2, Joan T. Merrill3, Joel M. Guthridge1, Virginia C. Roberts1 and Judith A. James4, 1Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Rheumatology and Clinical Immunology, University of Santo Tomas, Taguig City, Philippines, 3Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Arthritis and Clinical Immunology, University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: SLE is a multifaceted disease characterized by immune dysregulation and varied disease activity. Identifying mechanistic mediators of altered disease activity would help prevent damage…
  • Abstract Number: 2531 • 2015 ACR/ARHP Annual Meeting

    Hematologic Disorder during Pregnancy Associated with Adverse Pregnancy Outcomes Among Women with Systemic Lupus Erythematosus

    Sara K. Tedeschi1, Hongshu Guan2, Alexander Fine2, Bing Lu1, Karen H. Costenbader1 and Bonnie Bermas1, 1Rheumatology, Brigham & Women's Hospital, Boston, MA, 2Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Previous studies have found a relationship between overall systemic lupus erythematosus (SLE) activity and adverse pregnancy outcomes. We sought to investigate whether specific types…
  • Abstract Number: 2663 • 2015 ACR/ARHP Annual Meeting

    Evaluation of Anti-Cyclic Citrullinated Peptide Autoantibody Levels in Clinical Practice and Its Association with Disease Activity

    E Alemao1, KK Gandhi1, C Iannaccone2, M Frits2, JS Coblyn2, N Shadick2 and Michael Weinblatt2, 1Bristol-Myers Squibb, Princeton, NJ, 2Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Testing for anti-citrullinated peptide antibodies (ACPA) is included in the 2010 ACR classification criteria for RA. ACPA concentration, beyond ACPA positivity, is indicative of…
  • Abstract Number: 3045 • 2015 ACR/ARHP Annual Meeting

    Anti-Alpha-Enolase Antibodies in Behçet’s Disease: A Marker of Articular Disease Activity?

    Leandro L. Prado, Celio R. Gonçalves, Vilma S. T. Viana, Eloisa Bonfá and Carla G.S. Saad, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Diagnosis of Behçet´s disease (BD) is challenging because is based solely on clinical features. Articular involvement in this disease may mimic other diagnosis such…
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