Abstracts tagged "Disease Activity"

Abstract Number: 606 • 2015 ACR/ARHP Annual Meeting
Impaired Kidney Function Improves Treatment Response after 6 Months of Methotrexat Treatment in Rheumatoid Arthritis Patients
Paul Studenic¹, Farideh Alasti¹, Josef S. Smolen^2,3, Helmuth Haslacher⁴ and Daniel Aletaha⁵, ¹Department of Internal Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, ²Department of Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, ³2nd Department of Medicine, Hietzing Hospital, Vienna, Austria, ⁴Laboratory Medicine, Medical University Vienna, Vienna, Austria, ⁵Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria
Background/Purpose: Methotrexate (MTX) and leflunomide are categorized as DMARDs of first choice in treating rheumatoid arthritis patients. MTX should be used cautiously in patients with…
Abstract Number: 997 • 2015 ACR/ARHP Annual Meeting
Feasibility and Influential Factors in Performing Self-Evaluation of DAS28 with Smart System of Disease Management (SSDM) By RA Patient in China
Mu Rong¹, Fei Xiao², Chun Li³, Jianlong Guan⁴, Yan Shen⁴, Dongbao Zhao⁵, Xia Xu⁶, Lindi Jiang⁷, Huiyong Chen⁷, Li Su⁸, Yuhua Jia², Li Zhang², Yuan Liu² and Zhan-Guo Li³, ¹Department of Rheumatology and Immunology, People's Hospital, Beijing University Medical School, Beijing, China, ²Gothic Internet Technology Corporation, Shanghai, China, ³Department of Rheumatology & Immunology, People's Hospital, Beijing University Medical School, Beijing, China, ⁴Huadong Hospital Affiliated to Fudan University, Shanghai, China, ⁵ShangHai ChangHai Hospital, ShangHai ChangHai Hospital, ShangHai, China, ⁶Department of Rheumatology and Immunology, Changhai Hospital,Second Military Medical University,, Shanghai, China, ⁷Zhongshan Hospital, Fudan University, Shanghai, China, ⁸Longhua Hospital Shanghai University of TCM, Shanghai, China
Background/Purpose: Regular evaluations of rheumatoid arthritis (RA) disease activities with disease activity score in 28 joints (DAS28) are critical steps to reach the goal of…
Abstract Number: 1689 • 2015 ACR/ARHP Annual Meeting
Cross Sectional Study Investigating the Effect of the Presence of Fibromyalgia on Common Clinical Disease Activity Indices in Patients with Psoriatic Arthritis
Shay Brikman¹, Victoria Furer², Yonatan Wolman³, Sara Borok Lev-Ran⁴, Ari Polachek⁵, Ofir Elalouf², Amir Sharabi⁶, Ilana Kaufman¹, Daphna Paran⁵ and Ori Elkayam⁶, ¹Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ²Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, ³Medicine B, Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁴Tel Aviv Sourasky Medical Center, Tel AViv, Israel, ⁵Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁶Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Background/Purpose: To study the effect of the presence of fibromyalgia (FMS) on common clinical disease activity indices in patients with psoriatic arthritis (PsA). Methods: Seventy…
Abstract Number: 2479 • 2015 ACR/ARHP Annual Meeting
The Association Between Social Networks, Disease Activity, and Pain in Rheumatoid Arthritis
Taysir G. Mahmoud¹, Christine Iannaccone², Jing Cui², Yvonne C. Lee³, Michael Weinblatt⁴ and N Shadick⁵, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, ³Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology & Allergy, Brigham and Women's Hosp, Boston, MA
The Association between Social Network, Disease Activity, and Pain in Rheumatoid ArthritisBackground/Purpose: Current research suggests that high social network status is related to lower levels…
Abstract Number: 2615 • 2015 ACR/ARHP Annual Meeting
Changes in a Patient-Reported Measure of Physical Function, PF-10a, Are Most Strongly Associated with Changes in the Patient Global Assessment Portion of a Composite Measure of RA Disease Activity
Elizabeth R. Wahl^1,2, Andrew Gross², Vladimir Chernitskiy², Patricia P. Katz² and Jinoos Yazdany³, ¹Medicine/Rheumatology, San Francisco Veterans Affairs Medical Center, San Francisco, CA, ²Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ³University of California, San Francisco, San Francisco, CA
Background/Purpose: A brief patient-reported measure of physical function, the PROMIS PF-10a, is sensitive to changes in disease activity among patients with rheumatoid arthritis (RA). However,…
Abstract Number: 2878 • 2015 ACR/ARHP Annual Meeting
Treating Axial Spondyloarthritis to Target: Influence of the Population Characteristics and Comorbidities in Reaching Ankylosing Spondylitis Disease Activity Score (ASDAS) Inactive Disease in a Cohort of Patients Treated with Tnfalpha Inhibitors Agents
Sara Monti, Veronica Codullo, Vittorio Grosso, Silvia Breda, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy
Background/Purpose: The treat to target strategy (T2T), aiming at inactive disease (ID), has become the recommended approach also in the field of axial-SpA (axSpA) (1). …
Abstract Number: 3185 • 2015 ACR/ARHP Annual Meeting
A Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach in the Clinical Care of Rheumatoid Arthritis Patients in the United States
Leslie Harrold^1,2, George W. Reed^1,2, J. Timothy Harrington³, Christine J. Barr¹, Katherine C. Saunders¹, Allan Gibofsky⁴, Eric M. Ruderman⁵, Tmirah Haselkorn⁶, Jeffrey D. Greenberg^1,7, Ani John⁶ and Joel M. Kremer⁸, ¹Corrona, LLC, Southborough, MA, ²University of Massachusetts Medical School, Worcester, MA, ³Joiner Associates, LLC, Madison, WI, ⁴Hospital for Special Surgery, New York, NY, ⁵Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Genentech, Inc, South San Francisco, CA, ⁷NYU School of Medicine, New York, NY, ⁸Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: We report the results of a cluster-randomized behavioral intervention trial designed to assess the impact of implementing a treat-to-target (T2T) approach vs usual care…
Abstract Number: 409 • 2015 ACR/ARHP Annual Meeting
Disease Activity, Disease Damage and Predictive Factors in Juvenile Onset Mixed Connective Tissue Disease – a Norwegian Nationwide Study
Siri Opsahl Hetlevik¹, Berit Flatø^1,2, Marite Rygg^3,4, Ellen Berit Nordal⁵ and Vibke Lilleby⁶, ¹Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, ²Department of Rheumatology, Oslo University Hospital, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, ³Department of Pediatrics, St Olav University Hospital, Trondheim, Norway, ⁴Department of Laboratory Medicine, Children's and Women's health, Norwegian University of Science and Technology, Trondheim, Norway, ⁵Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway, ⁶Rheumatology, Oslo University Hospital, Oslo, Norway
Background/Purpose: Mixed Connective Tissue Disease (MCTD) is a rare rheumatic disease with overlapping features from Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc) and Polymyositis. Juvenile…
Abstract Number: 620 • 2015 ACR/ARHP Annual Meeting
Evaluation of Patients from the Non-Biologic Arms of Inflammatory Arthritis Clinical Trials Identifies Several Predictors of Remission, As Well As, Distinct Responder Subgroups
Brian Tom¹ and Deborah P.M. Symmons², ¹Biostatistics Unit, Medical Research Council, Cambridge, United Kingdom, ²NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
Background/Purpose: The RA-MAP consortium is a UK flagship industry-academic partnership investigating clinical and biological predictors of disease outcome in patients with rheumatoid arthritis (RA). Methods:…
Abstract Number: 1027 • 2015 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Disease Activity Assessment Frequencies in Clinical Practices Do Not Support Treat-to-Target Care
David Sikes¹, James Bower², Drew Johnson³, J. Timothy Harrington², Rafia Khalil⁴, Edmund LaCour⁵, Michael Naarendorp⁶, Hillary Norton⁷ and Kathleen Thomas⁸, ¹Rheumatology, Florida Medical Clinic PA, Zephyrhills, FL, ²Joiner Associates LLC, Madison, WI, ³Crescendo Bioscience, Inc., South San Francisco, CA, ⁴Rafia Khalil Arthritis & Rheumatology Center, PC, Port Huron, MI, ⁵Dothan Medical Associates PC, Dothan, AL, ⁶Harlem Rhematology, LLC, New York, NY, ⁷Rheumatology, Santa Fe Rheumatology, Santa Fe, NM, ⁸Community Rheumatology, Noblesville, IN
Background/Purpose: Treat-to-Target (T2T) recommendations for rheumatoid arthritis (RA) care include standardized frequencies of disease activity (DA) assessment based on DA level. For this study, "on…
Abstract Number: 1691 • 2015 ACR/ARHP Annual Meeting
The Presence of Fibromialgia May Influence the Clinimetric Evaluation of Patients with Ankylosing Spondylitis, but Has No Impact on Disease Activity Assessment
Emilio Buschiazzo¹, Natalia Zamora², Fernando Andres Sommerfleck³, Romina Rojas Tessel⁴, Mariana Benegas⁵, Pablo Arturi^6,7, Maria Elena Crespo⁴, Emilce Schneeberger⁸ and Gustavo Citera², ¹Rheumatology, Hospital Sr Del Milagro, Salta, Argentina, ²Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ³Rheumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Hospital Sr Del Milagro, Salta, Argentina, ⁵Sanatorio Mitre, Buenos Aires, Argentina, ⁶Rheumatology, Instituto de Rehabilitacion Psicofisica and Fundacion Reumatologica Argentina, Buenos Aires, Argentina, ⁷Rheumatology, Hospital Italiano de La Plata, La Plata, Argentina, ⁸Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina
Background/Purpose: Fibromyalgia (FM) can be present concomitantly in patients with Ankylosing Spondylitis (AS). It may overestimate the evaluation of disease activity, resulting in more intensive…
Abstract Number: 2481 • 2015 ACR/ARHP Annual Meeting
Work Disability in a Cohort of Patients with Psoriatic Arthritis
Cecilia Zaffarana¹, Osvaldo Luis Cerda¹, Josefina Gallino Yanzi¹, Margarita Landi¹, Emilce Schneeberger¹, Ignacio Carrillo¹, María del Carmen Gonzalez Guzmán¹, Jose A Maldonado Cocco¹, Susana Gagliardi¹ and Gustavo Citera², ¹Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Rheumatology, Consultorios Reumatológicos Pampa, Buenos Aires, Argentina
Background/Purpose: Several studies showed that unemployment and work disability are high in patients with Psoriatic Arthritis (PsA). Te purpose of this study is to evaluate work…
Abstract Number: 2619 • 2015 ACR/ARHP Annual Meeting
Clinical Usefulness of Periodic Detection of Serum 14-3-3Î· for Predicting Efficacy of Tocilizumab in RA
Akira Sagawa¹, Takuya Isayama², Makoto Kaneda³, Yuan Gui⁴, Anthony Marotta⁵ and Jiro Arai², ¹Sagawa Akira Rheumatology Clinic, Sapporo, Japan, ²Medical and Biological Laboratories Co., Ltd., Ina, Japan, ³MBL Europe, Diegem, Belgium, ⁴Augurex Life Sciences Corp., North Vancouver, BC, Canada, ⁵1423 Dempsey Road, Augurex Life Sciences Corp., North Vancouver, BC, Canada
Background/Purpose: Serum 14-3-3η is a diagnostic marker for RA. Recent in vitro evidence indicates that it may play a casual role in the pathogenesis of…
Abstract Number: 2881 • 2015 ACR/ARHP Annual Meeting
Infliximab in Spondyloarthritis Patients: Utility of Drug Level Monitoring
Claudia Deaconu¹, Diana Mazilu², Laura Grosanu², Ioana Saulescu², Andreea Borangiu², Cecilia Gainaru³, Cosmin Constantinescu², Violeta Bojinca², Violeta Vlad¹, Andra Balanescu², Denisa Predeteanu², Ruxandra Ionescu² and Daniela Opris², ¹Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ²University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ³"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
Background/Purpose: Spondyloarthritides, a heterogeneous group of chronic, inflammatory disorders with overlapping organ and joint targeting, share the same therapeutic approach in regard to biological therapy.…
Abstract Number: 3206 • 2015 ACR/ARHP Annual Meeting
Inflammation on MRI in Sacroiliac-Joints and Spine Is Longitudinally Related to Disease Activity in Male but Not in Female Patients with Axial Spondyloarthritis: 2-Year Data from the DESIR Cohort
Victoria Navarro-Compán¹, Sofia Ramiro², Robert B. M. Landewé³, Maxime Dougados⁴, Corinne Miceli-Richard⁵, Pascal Richette⁶ and Désirée van der Heijde⁷, ¹Rheumatology, University Hospital La Paz, Madrid, Spain, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands, ⁴Université Paris René Descartes and Hôpital Cochin, Paris, France, ⁵Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France, ⁶Université Paris Diderot, UFR médicale, Paris, France; APHP Hôpital Lariboisière, Fédération de Rhumatologie and Inserm U1132, Hôpital Lariboisière, Paris, France, ⁷Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: In patients with axial spondyloarthritis (axSpA), clinical disease activity measures (DA) have been longitudinally related to radiographic progression. Interestingly, a gender disparity has been…

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