Abstracts tagged "Disease Activity"

Abstract Number: 3106 • 2016 ACR/ARHP Annual Meeting
A Simple Test for Assessing and Monitoring SLE Disease Activity Status
Chaim Putterman¹, Michael Rowe², Joseph Barten Legutki², Theodore M. Tarasow² and Kathryn Sykes², ¹Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY, ²HealthTell, Inc, san ramon, CA
Background/Purpose: SLE patients can experience chronically active disease, remissions and flares, or long periods of quiescence. Accurately assessing disease activity is crucial for prescribing appropriate…
Abstract Number: 160 • 2016 ACR/ARHP Annual Meeting
Ultrasound Assessment of Rheumatoid Arthritis Patients. External Validation and Inter-Rater Reliability of a 4-Joint Ultrasonographic Scoring System
Tomas Cazenave¹, María Victoria Martire^2,3, Christian A. Waimann^4,5, Javier Rosa⁶, Marcelo Audisio⁷, Ana Bertoli⁸, Guillermo Py⁹, Santiago Ruta⁶, Josefina Marin¹⁰, Johana Zacariaz⁶, Cristian Troitiño¹¹, Mariana Benegas¹², Lida Santiago¹³, Patricio Tate¹⁴, Walter J. Spindler¹⁵, Horacio Berman¹⁶, María Julia Santa Cruz¹⁷, Paula Kohan¹⁸, Silvia Beatriz Papasidero¹⁹, Gustavo Citera²⁰ and Marcos G. Rosemffet¹, ¹Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ³Rheumatology, Hospital Italiano de La Plata, La Plata, Argentina, ⁴Escuela Superior de Ciencias de la Salud, UNICEN., Olavarria,, Argentina, ⁵Rheumatology, Hospital Dr. Hector Cura, Olavarria, Argentina, ⁶Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, ⁷Servicio de Reumatología del Hospital Nacional de Clínicas, Córdoba, Argentina, ⁸Instituto Reumatológico Strusberg, Córdoba, Argentina, ⁹Servicio de Reumatología del Hospital Nacional de Clínicas, Córdoba., Cordoba, Argentina, ¹⁰Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹¹Reumatologia, Hospital Bernardino Rivadavia, CAPITAL FEDERAL, Argentina, ¹²PSORIAHUE, Buenos Aires, Argentina, ¹³Organizacion Medica de Investigacion, Buenos Aires, Argentina, ¹⁴Organizacion Médica de Investigación, Buenos Aires, Argentina, ¹⁵Centro Médico Privado de Reumatología, Tucuman, Argentina, ¹⁶Centro Médico Privado de Reumatología, Tucumán, Argentina, ¹⁷Hospital Dr. E. Tornú, Buenos Aires, Argentina, ¹⁸Hospital Dr. E. Tornu, Buenos Aires, Argentina, ¹⁹Rheumatology Department, Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, ²⁰Rheumatology Section, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina
Background/Purpose: Although Ultrasound (US) has demonstrated to be a sensitive and specific tool, its feasibility in daily clinical practice is still under debate. We have…
Abstract Number: 529 • 2016 ACR/ARHP Annual Meeting
The Relationship Between Promis and CDAI Scores, Disease Duration, Age and Gender in Patients with Rheumatoid Arthritis
Alicia Lieberman¹, Judith Baumhauer², Chris Dasilva² and Allen P. Anandarajah³, ¹Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ²Orthopedic surgery, University of Rochester Medical Center, Rochester, NY, ³Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY
Background/Purpose: PROMIS (Patient-Reported Outcomes Measurement Information System) is a self-reported and parent-reported measure of global, physical, mental, and social health for the general population…
Abstract Number: 794 • 2016 ACR/ARHP Annual Meeting
Development and Initial Validation of a Novel Lupus Disease Activity Index to Account for Glucocorticoids: Sledai-2K Glucocorticoids Index (SGI)
Zahi Touma¹, Dafna D Gladman², Jiandong Su³ and Murray Urowitz¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: It is challenging to describe disease activity in SLE in the context of multiple levels of glucocorticoids (GC) treatment. We aim to develop and…
Abstract Number: 1367 • 2016 ACR/ARHP Annual Meeting
Long-Term Outcomes and Their Predictors in Patients with Juvenile Idiopathic Inflammatory Myopathies of Adult Age: A Referral Population Study
Sam Serafi¹, Vladislav Tsaltskan², Anna Yakovleva³, Heidi Sami¹, Frederick W. Miller⁴, Rodolfo Curiel¹, Olcay Y. Jones^1,5 and Lisa G. Rider^1,4, ¹Rheumatology, George Washington University, Washington, DC, ²Internal Medicine, George Washington University, Washington, DC, ³Department of Microbiology, Immunology, and Tropical Medicine., George Washington University, Washington, DC, ⁴Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, Bethesda, MD, ⁵Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD
Background/Purpose: To investigate the long-term outcomes and prognostic factors for pts with juvenile-onset idiopathic inflammatory myopathies (JIIM) who are currently adults. Methods: Adults with JIIM…
Abstract Number: 1538 • 2016 ACR/ARHP Annual Meeting
Lower Ratings of Pain Intensity in Older Adults Lead to Underestimation of Disease Activity By Disease Activity Score 28-C-Reactive Protein (DAS28-CRP) in Patients with Rheumatoid Arthritis
Yong Gil Hwang¹, Juan (June) Feng², Heather Eng², Jason Lyons², Anthony Fabio² and Larry W. Moreland¹, ¹Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA
Background/Purpose: To investigate the influence of age on the components of the 28-joint Disease Activity Score (DAS28)-C-reactive protein (CRP) in patients with rheumatoid arthritis…
Abstract Number: 1817 • 2016 ACR/ARHP Annual Meeting
A Longitudinal Analysis of Change in Lupus Disease Activity Pattern in Hopkins Lupus Cohort Using a Multistate Markov Model Approach
Wei Fu¹ and Michelle Petri², ¹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a multi-systemic inflammatory disease with extreme variability of its activity over time. We have described three main patterns: long…
Abstract Number: 2461 • 2016 ACR/ARHP Annual Meeting
Identifying Flare in Rheumatoid Arthritis: What Is the Threshold?
Elena Myasoedova¹, Cynthia S. Crowson², John M. Davis III³, Sherine E. Gabriel⁴ and Eric L. Matteson¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Dean's Office, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: The flare-assessment in RA (FLARE) questionnaire was developed for the detection of disease activity flares in patients with rheumatoid arthritis (RA) based on the…
Abstract Number: 2657 • 2016 ACR/ARHP Annual Meeting
Withdrawal of Nonsteroidal Anti-Inflammatory Drugs in Rheumatoid Arthritis Patients with Low Disease Activity
Dong Jin Go^1,2, Kichul Shin³, Han Joo Baek⁴, Seong-Wook Kang⁵, Young Mo Kang⁶, Jae-Bum Jun⁷, Yun Jong Lee⁸, Sung-Hwan Park⁹ and Yeong Wook Song^10,11, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, The Republic of, ²Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea, ⁵Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, South Korea, ⁷Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, The Republic of, ⁸Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea, ⁹Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea, ¹⁰Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, ¹¹Department of Molecular Medicine and Biopharmaceutical Sciences, BK21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, South Korea
Background/Purpose: Although nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in relieving joint pain in rheumatoid arthritis (RA) patients, long-term use of NSAIDs can cause adverse effects.…
Abstract Number: 2831 • 2016 ACR/ARHP Annual Meeting
Associations of BAFF and Anti-BAFF Autoantibodies with Disease Activity in Oriental Systemic Lupus Erythematosus
Hwee-Siew Howe¹, Bernard Thong², Kok Ooi Kong³, Hiok-Hee Chng², Tsui Yee Lian², Faith Chia², Karine Tay², Tang Ching Lau⁴, Weng Giap Law², Ee Tzun Koh⁵ and Bernard Pui Lam Leung^6,7, ¹Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, SINGAPORE, Singapore, ²Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, ., Singapore, ³Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore, ⁴Yong Loo Lin School of Medicine,, National University of Singapore, ., Singapore, ⁵Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, ., Singapore, ⁶Physiology, National University of Singapore, ., Singapore, ⁷Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital, ., Singapore
Background/Purpose: B cell activating factor (BAFF) is implicated in the pathogenesis of systemic lupus erythematosus (SLE). A previous small scale study reported that endogenous neutralizing…
Abstract Number: 3181 • 2016 ACR/ARHP Annual Meeting
The Utility of Urinalysis in Determining the Risk of Renal Relapse in ANCA-Associated Vasculitis
Rennie L. Rhee¹, John C. Davis², Linna Ding³, Fernando Fervenza⁴, Gary S. Hoffman⁵, Cees G.M. Kallenberg⁶, Carol A. Langford⁷, W Joseph McCune⁸, Paul A. Monach⁹, Philip Seo¹⁰, Robert F. Spiera¹¹, Eugene William St.Clair¹², Ulrich Specks⁴, John H. Stone¹³ and Peter A. Merkel¹⁴, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Baxalta, Cambridge, MA, ³NIH, Bethesda, MD, ⁴Mayo Clinic, Rochester, MN, ⁵Rheumatology, Cleveland Clinic, Cleveland, OH, ⁶Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁷Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ⁸Int Med/ Rheum, University of Michigan, Ann Arbor, MI, ⁹Rheumatology, Boston University School of Medicine, Boston, MA, ¹⁰Medicine, Johns Hopkins University, Baltimore, MD, ¹¹Hospital for Special Surgery, Cornell, New York, NY, ¹²Rheumatology and Immunology, Duke University, Durham, NC, ¹³Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ¹⁴Division of Rheumatology, Univ of Pennsylvania; Perelman School of Med, Philadelphia, PA
Background/Purpose: The significance of persistent hematuria or proteinuria in patients with ANCA-associated vasculitis (AAV) who are in clinical remission is still unclear. This study…
Abstract Number: 175 • 2016 ACR/ARHP Annual Meeting
Suppressor of Cytokine Function One (SOCS1) Is Elevated in Non-Classical Monocytes and Correlates with Disease Activity in Systemic Lupus Erythematosus Patients
Talha Khawar¹, Jessica Cooke², Nasim Daoud³, Vaneet Sandhu⁴, Willie Davis², Warren Peters⁵, Karina Marianne D. Torralba⁶, Michelle T. Ngo⁶, Sheila Lezcano¹, Kimberly J. Payne^7,8 and Abby Jones Weldon⁹, ¹Rheumatology, Loma Linda University Medical Center, Loma Linda, CA, ²Department of Pharmaceutical and Administrative Sciences, School of Pharmacy, Loma Linda University, Loma Linda, CA, ³Division of Rheumatology, Loma Linda University Medical Center, Loma Linda, CA, ⁴Division of Rheumatology, Loma Linda University, Loma Linda, CA, ⁵Department of Preventative Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, ⁶Rheumatology, Loma Linda University, Loma Linda, CA, ⁷Center of Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA, ⁸Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA, ⁹Loma Linda University, Loma Linda, CA
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease resulting from dysregulated innate and adaptive immune components that result in an inflammatory response. Cytokines produced…
Abstract Number: 540 • 2016 ACR/ARHP Annual Meeting
The Importance of Outcome Measures in Rheumatoid Arthritis – Validity of the Routine Assessment of Patient Index Data 3 in a Real World Setting
Sergio Schwartzman¹, Keith Knapp^2,3, Gary Craig^2,3, Karen Ferguson^2,3 and Discus Analytics, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Arthritis Northwest PLLC., Spokane, WA, ³Discus Analytics LLC., Spokane, WA
The Importance of Outcome Measures in Rheumatoid Arthritis - Validity of the RAPID3 (Routine Assessment of Patient Index Data 3) in a United States “Real…
Abstract Number: 797 • 2016 ACR/ARHP Annual Meeting
Randomized Clinical Trials of Systemic Lupus Erythematosus: Evaluating Differences in the Enrolled Populations
Niti Goel^1,2, Brandon Barrett³, Ann Duncan⁴, Margaret-Beth Gallagher¹ and Marsha Mackey³, ¹Quintiles, Inc., Durham, NC, ²Duke University School of Medicine, Durham, NC, ³Quintiles, Inc., Rockville, MD, ⁴Quintiles, Inc., Reading, Berkshire, United Kingdom
Background/Purpose: Background/Purpose: Randomized controlled trials (RCTs) in SLE identify specific populations of interest for eligibility, but still vary in the recruited populations. These differences may…
Abstract Number: 1370 • 2016 ACR/ARHP Annual Meeting
Development and Validation of a Composite Disease Activity Score for Juvenile Dermatomyositis
Silvia Rosina¹, Alessandro Consolaro¹, Pieter van Dijkhuizen¹, Kiran Nistala², Nicola Ruperto¹, Clarissa Pilkington³ and Angelo Ravelli¹, ¹Rheumatology, Giannina Gaslini Institute, Genova, Italy, ²Centre for Rheumatology, University College London, London, United Kingdom, ³Paediatric Rheumatology, Great Ormond Street Hospital NHS Trust, London, United Kingdom
Background/Purpose: JDM is a multisystem vasculopathic disease that primarily affects the skin and muscles. Most tools for assessment of disease activity in JDM are lenghty,…

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