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Abstracts tagged "Disease Activity"

  • Abstract Number: 1276 • ACR Convergence 2023

    Multimorbidity Burden Predicts Lower Likelihood of Remission in Patients with Rheumatoid Arthritis

    Cynthia Crowson, Chanakya Kodishala, Tina Gunderson, Atkinson Elizabeth, Vanessa Kronzer, John Davis, Courtney Arment, Delamo Bekele, Thomas Mason, Lynne Peterson, Kerry Wright and Elena Myasoedova, Mayo Clinic, Rochester, MN

    Background/Purpose: Seropositivity has historically been associated with poor disease outcomes in patients with rheumatoid arthritis (RA). Seronegative RA is on the rise and is associated…
  • Abstract Number: 1408 • ACR Convergence 2023

    Impact of Disease Activity on Functional Impairment in Patients with Spondyloarthritis Is Different According to the Degree of Radiographic Progression: Result from SNUH-AS Cohort

    Ji In Jung1, Ju Yeon Kim2, Jin Kyun Park3, Eun Young Lee3, Eun Bong Lee2 and Jun Won Park2, 1Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, 2Seoul National University Hospital, Seoul, South Korea, 3Seoul National University College of Medicine, Seoul, South Korea

    Background/Purpose: Although previous studies suggested that physical functioning is largely driven by disease activity in patients with spondyloarthritis (SpA), its relationship to radiographic progression has…
  • Abstract Number: 1672 • ACR Convergence 2023

    Association of COVID-19 Vaccinations with Flares of Systemic Rheumatic Disease: A Case-Crossover Study

    Genna Braverman1, Medha Barbhaiya2, Minerva Nong1, Vivian Bykerk3, Nathaniel Hupert4, Colby Lewis V4 and Lisa Mandl2, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 3Department of Rheumatology, Hospital for Special Surgery, New York, NY, 4Weill Cornell Medicine, New York, NY

    Background/Purpose: Fear of flare contributes to COVID-19 vaccine hesitancy in patients with systemic rheumatic diseases (SRD). Accurately ascertaining post-vaccine SRD flares and differentiating them from…
  • Abstract Number: 2187 • ACR Convergence 2023

    Association Between Illness Perception, Anxiety and Depression State, Disease Activity and Glucocorticoid Therapy in Patients with Sjӧgren’s Syndrome

    Chiara Baldini1, Elena Elefante2, Inmaculada Conception Navarro Garcia2, Francesco Ferro3, Gaetano La Rocca4, Giovanni Fulvio1, Silvia Fonzetti5, Michele Moretti6 and Marta Mosca2, 1University of Pisa, Pisa, Italy, 2Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, Pisa, Italy, 3Clinical and Experimental Medicine Department, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, 4University of Pisa, Rheumatology Unit, Pisa, Italy, 5AOUP, Pisa, Italy, 6Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

    Background/Purpose: Sjӧgren's syndrome (SS) may affect several aspects of patients' daily lives, leading to impairment of quality of life and patient functioning. Aims of this…
  • Abstract Number: 2317 • ACR Convergence 2023

    Effect of SLE-DAS Remission on Quality of Life in Patients with Systemic Lupus Erythematosus: A Cross-sectional Validation Study

    Fung Lam1, Chi Hung To1 and Chi Chiu Mok2, 1Pok Oi Hospital, Hong Kong, Hong Kong, 2Tuen Mun Hospital, Hong Kong, Hong Kong

    Background/Purpose: The SLE Disease Activity Score (SLE-DAS) has been developed and validated in Italian patients with SLE. The objective of this study was to evaluate…
  • Abstract Number: 2559 • ACR Convergence 2023

    Clinical Manifestations and Immunomodulatory Treatment in Patients with Relapsing Polychondritis

    Roger Yang1, Rennie Rhee2, Kaitlin Quinn3, Naomi Amudala2, Peter Grayson4, Peter Merkel2, Marcela Ferrada5 and Shubhasree Banerjee2, 1University of Pennsylvania, Montréal, QC, Canada, 2University of Pennsylvania, Philadelphia, PA, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 4National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Chevy Chase, MD, 5NIH, Bethesda, MD

    Background/Purpose: Relapsing polychondritis (RP) is a rare systemic inflammatory disease without standard treatment guidelines. This study aims to investigate the clinical characteristics, current treatment approaches,…
  • Abstract Number: 0220 • ACR Convergence 2023

    Paxlovid (Nirmatrelvir Plus Ritonavir) in Patients with Underlying Rheumatological Diseases, in Preventing COVID-19 Related Hospitalization and Death

    Faiza Javed, Tony Mangino and Paramarajan Piranavan, University of Kentucky College of Medicine, Lexington, KY

    Background/Purpose: The benefits of antiviral therapy in the COVID-19 patients with underlying rheumatic disease with or without immunosuppression are not entirely clear. The goal of…
  • Abstract Number: 0445 • ACR Convergence 2023

    Comparison of the Efficacy, Safety and Immunogenicity of a Proposed Biosimilar MSB11456 with Tocilizumab Reference Product in Moderate-to-severe Rheumatoid Arthritis: Results of a Randomized Double-blind Study

    Anna Zubrzycka-Sienkiewicz1, Maria Misterska-Skora2, Małgorzata Socik Pojawa3, Kamilla Klama4, Martin Ullmann5, Corinne Petit-Frere5, Andras Illes5, Peter Baker5, Joëlle Monnet5 and Jan Brzezicki6, 1Reumatika - Centrum Reumatologil, Warsaw, Poland, 2Centrum Medyczne Oporów, Wrocław, Poland, 3MICS Centrum Medyczne Warszawa, Warsaw, Poland, 4Solumed Centrum Medyczne, Poznań, Poland, 5Fresenius Kabi SwissBiosimilars, Eysins, Switzerland, 6Centrum Kliniczno Badawcze, Elbląg, Poland

    Background/Purpose: Tocilizumab is an anti‑interleukin‑6 receptor monoclonal antibody indicated for treating rheumatoid arthritis (RA) and other inflammatory diseases. MSB11456 is a proposed biosimilar to US‑licensed…
  • Abstract Number: 0587 • ACR Convergence 2023

    Impact of up to 24 Months Intravenous (IV) Belimumab (BEL) Treatment on Steroid Use and Disease Activity in Patients with SLE in Clinical Practice: Additional Post Hoc Pooled Analysis of Multicountry OBSErve Cohort Data

    Daniel Moldaver1, Seth Anderson2, Marguerite Bracher3, Roger A. Levy4, Holly A. Quasny5, Robert Wood6, Rosie Wild6, Alexandra Cusmano6 and Elke Rottier6, 1GlaxoSmithKline, Value Evidence and Outcomes, Ontario, Canada, 2GlaxoSmithKline, Value Evidence and Outcomes, Collegeville, PA, 3GlaxoSmithKline, Value Evidence and Outcomes, Stevenage, United Kingdom, 4GlaxoSmithKline, Global Medical Affairs, Collegeville, PA, 5GlaxoSmithKline, Research & Development, Durham, NC, 6Adelphi Real World, Real-World Evidence, Cheshire, United Kingdom

    Background/Purpose: The clinical effectiveness of 6-month IV BEL use in SLE has previously been described in a post hoc pooled analysis from six OBSErve cohort…
  • Abstract Number: 0978 • ACR Convergence 2023

    Identifying Important Clinical Features for Predicting Remission in Patients with Rheumatoid Arthritis Treated with Biologics Using Machine Learning Model

    Ahmad Alsaber1, Adeeba AlHerz2, Balqees Alawadhi3, Parul Setiya4, KHULOUD MOHAMMED5, Adel Al-Awadhi6, Waleed Al-Kandari7, Eman Hasan8, Khaled Mokaddem9, Aqeel Ghanem10, Youssef Bartella11, Mohammed Hussain8, Naser Alhadhood12, Yaser Ali13, Ebrahim Nahar13, Ali Aldei8, Ahmad Alenizi14, Sawsan Hayat15, Fatemah Abutiban16 and Fatemah Abutiban11, 1American University of Kuwait, Kuwait City, Kuwait, 2Al-Amiri Hospital, Al Asimah Governate, Kuwait, 3The Public Authority for Applied Education and Training, Kuwait City, Kuwait, 4GBPUAT, Department of Agrometerology, Pantnagar, India, 5Farwaniya Hospital, Kuwait, Kuwait, 6Kuwait University, Kuwait City, Kuwait, 7Farwaniya Hospital, Division of Rheumatology, Ministry of Health, Kuwait, Kuwait, 8Amiri Hospital, Division of Rheumatology, Kuwait City, Kuwait, 9Al-Amiri Hospital, Rheumatoid, Al Kuwayt, Kuwait City, Kuwait, 10Mubarak Al-Kabeer Hospital, Division of Rheumatology, Kuwait City, Kuwait, 11Farwaniya Hospital, Department of Rheumatology, Kuwait, Kuwait, 12Farwaniya Hospital, Kuwait City, Kuwait, 13Mubarak Al-Kabeer Hospital, Department of Rheumatology, Jabriya, Kuwait, 14Jahra Hospital, Al Jahra, NY, Kuwait, 15Ministry of Health - Kuwait, Jabriya, Kuwait, 16Jahra Hospital, Department of Medicine, Al Jahra, Kuwait

    Background/Purpose: Biologic disease-modifying antirheumatic drugs (bDMARDs) offer promising results for rheumatoid arthritis (RA) patients in general, but a substantial percentage of patients do not respond…
  • Abstract Number: 1292 • ACR Convergence 2023

    Active Rheumatoid Arthritis Patients Exhibit an Altered Serum Lipidomic Profile Directly Linked to Disease Activity, Which Is Reversed by Biologic and Targeted Synthetic DMARD

    Chary Lopez-Pedrera1, Laura Muñoz-Barrera2, Beatriz Vellón2, Rocio Guzman2, Tomás Cerdó2, Rafaela Ortega Castro3, Jerusalem Calvo4, Mª Angeles Aguirre5, Pedro Segui2, Ivan Arias de la Rosa6, Maria del Carmen Abalos-Aguilera7, Desiree Ruiz-Vilchez2, Christian Merlo-Ruiz2, Jose Javier Perez-Venegas8, Javier Godoy9, Dolores Ruiz-Montesinos10, Carmen Dominguez8, Carlos Rodriguez-Escalera11, Carmen Romero-Barco12, Antonio Fernandez-Nebro12, Natalia Mena Vazquez13, Julia Uceda Montañez14, Charo Santos14, Nuria Barbarroja15, Eduardo Collantes Estévez16, Mª del Mar Malagon2, Alejandro Escudero Contreras4 and Carlos Perez-Sanchez17, 1IMIBIC - Reina Sofia Hospital, Córdoba, Spain, 2IMIBIC/Reina Sofia Hospital/University of Cordoba, Córdoba, Spain, 3Hospital Reina Sofía, Cordoba, Spain, 4Reina Sofia University Hospital, Córdoba, Spain, 5Reina Sofía University Hospital/ Rheumatology Department, Córdoba, Spain, 6IMIBIC/Reina Sofia Hospital/University of Cordoba. Rheumatology service. Cordoba. Spain, Cordoba, Spain, 7Rheumatology Department, Reina Sofia University Hospital/Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Córdoba, Spain, 8Virgen Macarena University Hospital, Sevilla, Spain, 9Jaen University Hospital, Jaen, Spain, 10Hospital Universitario Virgen Macarena, Sevilla, Spain, 11Virgen de la Victoria Hospital, Malaga, Spain, 12Hospital Regional Universitario de Málaga, Malaga, Spain, 13IBIMA, Málaga, Spain, 14Hospital Virgen de Valme, Sevilla, Spain, 15University of Cordoba, Córdoba, Spain, 16Maimonides Biomedical Research Institute of Cordoba (IMIBIC)/University of Cordoba, Cordoba, Spain, 17IMIBIC, Córdoba, Spain

    Background/Purpose: Lipid metabolism impacts immune cell plasticity, activation, differentiation, and function, making the analysis of the lipidomic profile crucial in understanding chronic inflammatory diseases like…
  • Abstract Number: 1412 • ACR Convergence 2023

    Improvements in Patient-Reported Outcomes Through 6 Months of Guselkumab Treatment in Patients with Active Psoriatic Arthritis: Real-World Data from the CorEvitas Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Philip J. Mease1, Alexis R Ogdie2, John Tesser3, Natalie shiff4, Iris Lin5, Soumya Chakravarty6, Mike Kelleman7, Rhiannon Dodge7, Robert McLean7, Aaron Broadwell8, Arthur Kavanaugh9 and Joseph F. Merola10, 1Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 2University of Pennsylvania, Philadelphia, PA, 3Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, 4Immunology, Janssen Scientific Affairs, LLC / Adjunct, Community Health and Epidemiology, University of Saskatchewan, Horsham, PA, 5Janssen, Horsham, PA, 6Immunology, Janssen Scientific Affairs, LLC / Division of Rheumatology, Drexel University College of Medicine, Villanova, PA, 7CorEvitas, LLC, Waltham, MA, 8Department of Rheumatology, Rheumatology and Osteoporosis Specialists, Shreveport, LA, 9Division of Rheumatology, Allergy, and Immunology, University of California San Diego, La Jolla, CA, 10Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Guselkumab (GUS) has demonstrated significant efficacy across disease domains in controlled clinical trials of patients (pts) with active PsA.1,2 Recent CorEvitas PsA/SpA Registry analyses…
  • Abstract Number: 1685 • ACR Convergence 2023

    SLE Disease Activity Is a More Important Risk Factor Than Immunosuppression for Acquiring Human Papillomavirus (HPV) Infection in Systemic Lupus Erythematosus Patients

    Zehra Kazmi1, Carlos Lorenzo2 and Agustin Escalante3, 1University of Texas Health Science Center at San Antonio, San Antonio, TX, 2UT Heath San Antonio, Shavano Park, TX, 3UT Health Science Center at San Antonio, San Antonio, TX

    Background/Purpose: SLE patients have increased rates of HPV infection and cervical cancer. Although some factors are recognized for HPV infection in SLE, the relationship with…
  • Abstract Number: 2198 • ACR Convergence 2023

    Which Factors Are Associated with Clinically High Disease Activity in Axial Spondyloarthritis? Results from the International Map of Axial Spondyloarthritis (IMAS)

    Marco Garrido-Cumbrera1, Victoria Navarro-Compán2, Fernando Sommerfleck3, Christine Bundy4, Souzi Makri5, Jose Correa Fernandez6, Shashank Murlidhar Akerkar7, Jo Davies8, Elie Karam9, Asif Siddiqui10 and Denis Poddubnyy11, 1University of Seville, Sevilla, Spain, 2Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 3Sanatorio Julio Mendez, Buenos Aires, Argentina, 4Cardiff University, Cardiff, United Kingdom, 5Cyprus League for People with Rheumatism (CYLPER), Nicosia, Cyprus, 6Universidad de Sevilla, Health & Territory Research (HTR), Sevilla, Spain, 7Mumbai Arthritis Clinic, Mumbai, India, 8Axial Spondyloarthritis International Federation (ASIF), London, United Kingdom, 9Canadian Spondylitis Association (CSA), Toronto, ON, Canada, 10Novartis Pharma AG, Basel, Switzerland, 11Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Active axial spondyloarthritis (axSpA) is associated with poorer physical and mental health outcomes. This study aims to assess the prevalence of clinically active disease…
  • Abstract Number: 2321 • ACR Convergence 2023

    Does the Perspective of SLE Patients Match the Expert Opinion and Definitions of Remission and Low Disease Activity State? Prospective Analysis of 500 Patients from a Spanish Multicenter Cohort

    CORAL Mourino Rodriguez1, Jose-Maria Pego-Reigosa2, Iñigo Rúa-Figueroa3, Francisco Rubino4, Iñigo Hernández-Rodríguez5, Raúl Menor-Almagro6, Esther Uriarte Isacelaya7, Eva Tomero Muriel8, TAREK CARLOS SALMAN MONTE9, MARIA IRENE CARRION BARBERA9, Maria Galindo10, Esther Rodriguez almaraz10, Norman Jiménez11, Luis Ines12 and Irene Altabas Gonzalez13, 1Complejo Hospitalario Universitario de Vigo. IRIDIS (Investigation in Rheumatology and Immune-Mediated Diseases) Group, Galicia Sur Health Research Institute, Vigo, Spain, 2Rheumatology, Hospital do Meixoeiro, Vigo, Spain, 3Rheumatology, Hospital de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria, Spain, 4Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain, 5Hospital do Meixoeiro. Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 6Rheumatology, Hospital Jerez, Puerto De Santa María, Spain, 7Hospital Universitario de Donostia, Donostia, Spain, 8Rheumatology, Hospital La Princesa, Madrid, Spain, 9Hospital del Mar/Parc de Salut Mar-IMIM, Barcelona, Spain, 10Hospital Universitario 12 de Octubre, Madrid, Spain, 11IIRIDIS (Investigation in Rheumatology and Immune-Mediated Diseases) Group, Galicia Sur Health Research Institute., Vigo, Spain, 12Centro Hospitalar e Universitario de Coímbra, Coimbra, Portugal, 13Complejo Hospitalario Universitario de Vigo, IRIDIS (Investigation in Rheumatology and Immune-Mediated Diseases) Group, Galicia Sur Health Research Institute, Vigo, Spain

    Background/Purpose: There is no information available regarding whether the patient's perception of disease activity aligns with current definitions of DORIS 2021 remission and Lupus Low…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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